Exemplar Abstract for Streptomyces venezuelae Ehrlich et al. 1948 (Approved Lists 1980) emend. Nouioui et al. 2018.

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
George M Garrity
Keyword(s):  
Streptomyces Venezuelae

Exemplar Abstract for Streptomyces venezuelae Ehrlich et al. 1948 (Approved Lists 1980) emend. Nouioui et al. 2018.

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
George M Garrity
Keyword(s):  
Streptomyces Venezuelae

Exemplar Abstract for Streptomyces venezuelae Ehrlich et al. 1948 (Approved Lists 1980) emend. Nouioui et al. 2018.

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
George M Garrity
Keyword(s):  
Streptomyces Venezuelae

Nomenclature Abstract for Streptomyces venezuelae Ehrlich et al. 1948 (Approved Lists 1980) emend. Nouioui et al. 2018.

2003 ◽  
Author(s):  
Charles Thomas Parker ◽  
George M Garrity
Keyword(s):  
Streptomyces Venezuelae

scholarly journals Genes Required for Aerial Growth, Cell Division, and Chromosome Segregation Are Targets of WhiA before Sporulation in Streptomyces venezuelae

mBio ◽  
2013 ◽  
Vol 4 (5) ◽  
Author(s):  
Matthew J. Bush ◽  
Maureen J. Bibb ◽  
Govind Chandra ◽  
Kim C. Findlay ◽  
Mark J. Buttner
Keyword(s):  
Cell Division ◽  
Chromosome Segregation ◽  
Regulatory Networks ◽  
Liquid Culture ◽  
Biological Processes ◽  
Streptomyces Venezuelae ◽  
Content Type ◽  
Master Regulators ◽  
Aerial Growth ◽  
Genes Encoding

ABSTRACTWhiA is a highly unusual transcriptional regulator related to a family of eukaryotic homing endonucleases. WhiA is required for sporulation in the filamentous bacteriumStreptomyces, but WhiA homologues of unknown function are also found throughout the Gram-positive bacteria. To better understand the role of WhiA inStreptomycesdevelopment and its function as a transcription factor, we identified the WhiA regulon through a combination of chromatin immunoprecipitation-sequencing (ChIP-seq) and microarray transcriptional profiling, exploiting a new model organism for the genus,Streptomyces venezuelae, which sporulates in liquid culture. The regulon encompasses ~240 transcription units, and WhiA appears to function almost equally as an activator and as a repressor. Bioinformatic analysis of the upstream regions of the complete regulon, combined with DNase I footprinting, identified a short but highly conserved asymmetric sequence, GACAC, associated with the majority of WhiA targets. Construction of a null mutant showed thatwhiAis required for the initiation of sporulation septation and chromosome segregation inS. venezuelae, and several genes encoding key proteins of theStreptomycescell division machinery, such asftsZ,ftsW, andftsK, were found to be directly activated by WhiA during development. Several other genes encoding proteins with important roles in development were also identified as WhiA targets, including the sporulation-specific sigma factor σWhiGand the diguanylate cyclase CdgB. Cell division is tightly coordinated with the orderly arrest of apical growth in the sporogenic cell, andfilP, encoding a key component of the polarisome that directs apical growth, is a direct target for WhiA-mediated repression during sporulation.IMPORTANCESince the initial identification of the genetic loci required forStreptomycesdevelopment, all of thebldandwhidevelopmental master regulators have been cloned and characterized, and significant progress has been made toward understanding the cell biological processes that drive morphogenesis. A major challenge now is to connect the cell biological processes and the developmental master regulators by dissecting the regulatory networks that link the two. Studies of these regulatory networks have been greatly facilitated by the recent introduction ofStreptomyces venezuelaeas a new model system for the genus, a species that sporulates in liquid culture. Taking advantage ofS. venezuelae, we have characterized the regulon of genes directly under the control of one of these master regulators, WhiA. Our results implicate WhiA in the direct regulation of key steps in sporulation, including the cessation of aerial growth, the initiation of cell division, and chromosome segregation.

scholarly journals The fused anthranilate synthase from Streptomyces venezuelae functions as a monomer

2014 ◽  
Vol 400 (1-2) ◽  
pp. 9-15 ◽  
Author(s):  
Meseret Ashenafi ◽  
Prasad T. Reddy ◽  
James F. Parsons ◽  
W. Malcolm Byrnes
Keyword(s):  
Anthranilate Synthase ◽  
Streptomyces Venezuelae

Para-position derivatives of fungal anthelmintic cyclodepsipeptides engineered with Streptomyces venezuelae antibiotic biosynthetic genes

2004 ◽  
Vol 22 (7) ◽  
pp. 848-855 ◽  
Author(s):  
Koji Yanai ◽  
Naomi Sumida ◽  
Kaoru Okakura ◽  
Tatsuki Moriya ◽  
Manabu Watanabe ◽  
...  
Keyword(s):  
Para Position ◽  
Streptomyces Venezuelae ◽  
Biosynthetic Genes ◽  
Derivatives Of

A new metabolite of Streptomyces venezuelae: d-Threo-1-p-aminophenyl-2-dichloroacetamido-1,3-propanediol

1963 ◽  
Vol 103 (2) ◽  
pp. 159-163 ◽  
Author(s):  
Charlotte D. Stratton ◽  
Mildred C. Rebstock
Keyword(s):  
Streptomyces Venezuelae

Cloning and Expression of an rRNA Methylase Gene in Streptomyces Venezuelae Phage VWB

1987 ◽  
pp. 237-238
Author(s):  
J. Anne ◽  
L. Van Mellaert ◽  
H. Eyssen
Keyword(s):  
Cloning And Expression ◽  
Streptomyces Venezuelae ◽  
Methylase Gene
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