Determining Stability Constants of Complexes Between Ester Betulin Derivatives and β-Cyclodextrin by Affinity Capillary Electrophoresis
Keyword(s):
Inclusion complexes of ester betulin derivatives (pentacyclic lupane triterpenoids) with β-cyclodextrin (β-CD) were studied by affinity capillary electrophoresis. Stability constants were calculated from dependencies of viscosity-corrected effective electrophoretic mobilities on β-CD concentration (0-10 mM) in background electrolytes using nonlinear regression fitting. Logarithms of stability constants at 25 °C for 1:1 and 1:2 β-CD complexes of betulin 3,28-diphthalate, betulin 3,28-disuccinate and betulin 3,28-disulfate (95 % confidence interval) are 4.25 (4.16-4.32) and 7.27 (6.73-7.50), 4.38 (4.26-4.48) and 7.58 (6.90-7.84), 4.04 (4.00-4.08) and 5.91 (4.60-6.20), respectively
2018 ◽
Vol 1568
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pp. 197-204
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2020 ◽
Vol 412
(23)
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pp. 5615-5625
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2019 ◽
Vol 283
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pp. 325-331
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2013 ◽
Vol 78
(1-4)
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pp. 185-194
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