scholarly journals A rare case report on 90 day glaucoma due to branched retinal vein occlusion

Author(s):  
Jawahar Jyoti Kuli ◽  
Utkarsh Rai

A 19 year old female, presented to the ophthalmology OPD with pain and redness in her left eye since 30 days. Upon examination, there was no perception of light in left eye, both the pupils were mid-dilated and non-reactive to light stimulation. The left eye intra-ocular pressure (ATn) was 60 mm of Hg. On slit lamp examination, 3600 iris neovascularisation, ciliary congestion and corneal oedema were noted. Indirect gonioscopy revealed grade I angle closure in the left eye. Fundus examination of the affected eye revealed pale optic disc, CDR of 0.9:1, multiple dot and blot hemorrhages, suggestive of supero-temporal BRVO (branched retinal vein occlusion). Fundus fluorescein angiography revealed blocked fluorescence and leakage from neovascularization in the left eye. Conservative management with anti-glaucoma drugs failed to lower the IOP. Subsequently, pan-retinal photocoagulation (PRP) with intravitreal anti-VEGF (vascular endothelial growth factor) in the left eye followed by cyclo-cryoablation helped her symptoms to subside.

2019 ◽  
Vol 4 (1) ◽  
pp. e000249 ◽  
Author(s):  
Kimberly Spooner ◽  
Samantha Fraser-Bell ◽  
Thomas Hong ◽  
Andrew A Chang

PurposeReport 5-year outcomes of patients receiving anti-vascular endothelial growth factor (VEGF) for the treatment of macular oedema secondary to retinal vein occlusion (RVO.MethodsRetrospective review of eyes with RVO which initiated anti-VEGF treatment. Data including age, gender, visual acuity (VA) and injection numbers were obtained from medical records. Optical coherence tomography scans were graded for presence or absence of macular oedema and central foveal thickness (CFT). Macular perfusion was assessed on fundus fluorescein angiography by masked graders.Results68 eyes (31 branch RVO, BRVO; 35 central RVO, CRVO and 2 hemi-RVO) with 5 years of follow-up after initiation of anti-VEGF treatment. Mean change in VA at 5 years was + 9.6 ± 21.6 letters among CRVO eyes and + 14.2 ± 15.6 letters among eyes with BRVO (p=0.001). Vision of 20/40 or better was achieved in 65 % of treated eyes. The proportion of eyes with a three-line improvement of vision (15 letters) at 5 years was 22 %. Mean CFT decreased by 257.6 ± 249.8 µm in eyes with CRVO and 145.6 ± 143.3 µm in eyes with BRVO.ConclusionThe results confirm good long-term outcomes can be achieved with anti-VEGF therapy for RVO.


Macular edema secondary to retinal vein occlusions is a significant complication affecting the vision. Medical treatment of retinal vein occlusions first started with intraocular steroid injections and then enriched with intraocular Anti-VEGF (Vascular Endothelial Growth Factor) injections. But till now the length and frequency of therapy have not been defined clearly. In this review, the use of bevacizumab in the treatment of branch retinal vein occlusion and macular edema will be summarized in light of the current literature.


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