scholarly journals Spontaneous splenic rupture in a patient with chronic granulocytic leukemia

2021 ◽  
Vol 8 (9) ◽  
pp. 2786
Author(s):  
Hector Vergara Miranda ◽  
Raúl Omar Martínez Zarazúa ◽  
Mayra Alexandra Hernandez Ramírez ◽  
José Angel Rodríguez Briseño ◽  
Gerardo Enrique Muñoz Maldonado

Spontaneous splenic rupture is a rare phenomenon that is not associated with trauma. The most common causes of splenic rupture are hematological diseases (30.3%), inflammatory diseases (20%), infectious diseases (27.3%), drugs (9.2%), mechanical disorders (6.8%), and unknown causes (6.4%). Spontaneous splenic rupture secondary to hematological malignancy is rare; in this group of patients, chronic granulocytic leukemia is the main cause. The mechanism of spontaneous splenic rupture is uncertain. Three mechanisms have been suggested: the mechanical effect of leukemia and its infiltration in the spleen, especially if the capsule is invaded; splenic infarction with subsequent subcapsular hemorrhage and rupture of the splenic capsule, and coagulation abnormalities.

2020 ◽  
Author(s):  
Mohammadreza Mobayen ◽  
Saeed Yousefi ◽  
Mohammadsadegh Mousavi ◽  
Amin Shafighi Anbaran

Abstract Introduction: Splenic rupture is an emergency condition and the vast numbers of cases are secondary to trauma. Several underlying pathologies have also been associated with splenic rupture, such as hematological diseases, malignancies, and infectious and inflammatory diseases.Presentation of case: The patient was a 52-year-old man who referred to the Poursina Hospital in Rasht while complaining of abdominal pain from the day before hospitalization. The patient reported a history of lethargy, fever, and nausea. In the examinations performed, there was a brief tenderness in the patient's epigastrium. The patient was monitored and about 12 hours after hospitalization, ill appearance, respiratory (respiratory distress) symptoms, and high fever were reported for the patient. According to the examination, the patient was immediately transferred to the operating room and underwent laparotomy. During the operation, contrary to our expectations, a lot of blood (about 1000 cc) was observed in the patient's abdomen. After blood suctioning, the left upper quadrant (LUQ) was bleeding and the rupture of the spleen could also be observed. Therefore, a splenectomy was performed .In the examinations performed for the patient, the patient's rtPCR test confirmed COVID-19.Conclusion: The evaluation of the spontaneous splenic rupture (SSR) in our case shows that this type of risk should also be considered in patients with COVID-19 who referred to medical centers with abdominal pain, and if more cases are reported, the correctness of this process can be commented on.


BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mohammadreza Mobayen ◽  
Saeed Yousefi ◽  
Mohammadsadegh Mousavi ◽  
Amin Shafighi Anbaran

Abstract Background Splenic rupture is an emergency condition and a vast number of cases are secondary to trauma. Several underlying pathologies have also been associated with splenic rupture, such as hematological diseases, malignancies, and infectious and inflammatory diseases. Case presentation The patient was a 52-year-old man who referred to the Poursina Hospital in Rasht while complaining of abdominal pain from the day before hospitalization. The patient reported a history of lethargy, fever, and nausea. In the examinations performed, there was a brief tenderness in the patient’s epigastrium. The patient was monitored and about 12 h after hospitalization, ill appearance, respiratory (respiratory distress) symptoms, and high fever were reported for the patient. According to the examination, the patient was immediately transferred to the operating room and underwent laparotomy. During the operation, contrary to our expectations, a lot of blood (about 1000 cc) was observed in the patient’s abdomen. After blood suctioning, the left upper quadrant (LUQ) was bleeding and the rupture of the spleen could also be observed. Therefore, a splenectomy was performed. In the examinations performed for the patient, the patient’s rtPCR test confirmed COVID-19. Conclusion The evaluation of the spontaneous splenic rupture (SSR) in our case shows that this type of risk should also be considered in patients with COVID-19 who refer to medical centers with abdominal pain, and if more cases are reported, the correctness of this process can be commented on.


2007 ◽  
Vol 148 (29) ◽  
pp. 1381-1384 ◽  
Author(s):  
Márta Szokó ◽  
András Matolcsy ◽  
Gábor Kovács ◽  
Gábor Simon

A lépruptura a mononucleosis infectiosa ritka szövődménye, a betegek 0,1–0,5%-ánál következik be. Ez a betegség leggyakoribb halálos komplikációja. A mononucleosisra jellemző egyéb tünetek nélkül kialakuló spontán lépruptura különösen ritka, váratlan bekövetkezése miatt a fatális kimenetel lehetőségével fenyeget. A szerzők egy 16 éves, spontán lépruptura miatt splenectomizált fiú esetét ismertetik, akinél a szerológiai vizsgálatok friss Epstein–Barr-vírusinfekciót igazoltak, a mononucleosis infectiosa egyéb tünetei, jelei nélkül. Áttekintik a mononucleosisban kialakuló lépruptura diagnosztikáját és kezelését.


Pathology ◽  
2010 ◽  
Vol 42 ◽  
pp. S88-S89
Author(s):  
Andrew J. Gifford ◽  
David Nevell ◽  
Charles Chan ◽  
Kirsty McIlroy

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