Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer

Inhibitor Screening ◽

Potential Therapeutic Agent ◽

Abstract A212: A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor‐induced apoptosis in HCT116 colon carcinoma cells

10.1158/1535-7163.targ-09-a212 ◽

2009 ◽

Cited By ~ 1

Author(s):

Andrew J. Massey ◽

Jennifer Borgognoni ◽

Helen Browne ◽

Zoe Daniels ◽

Pawel Dokurno ◽

...

Keyword(s):

Colon Carcinoma ◽

Small Molecule ◽

Hsp90 Inhibitor ◽

Carcinoma Cells ◽

Colon Carcinoma Cells ◽

Molecule Inhibitor ◽

Induced Apoptosis

DNA-Directed Assembly Microarray for Protein and Small Molecule Inhibitor Screening

Methods in Molecular Biology - Drug Design and Discovery ◽

10.1007/978-1-61779-012-6_7 ◽

2011 ◽

pp. 127-140 ◽

Cited By ~ 3

Author(s):

Ng Jin Kiat ◽

Fritz Simeon ◽

Too Heng Phon ◽

Parayil Kumaran Ajikumar

Keyword(s):

Small Molecule ◽

Directed Assembly ◽

Inhibitor Screening ◽

A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-009-1194-3 ◽

2009 ◽

Vol 66 (3) ◽

pp. 535-545 ◽

Cited By ~ 190

Author(s):

Andrew J. Massey ◽

Douglas S. Williamson ◽

Helen Browne ◽

James B. Murray ◽

Pawel Dokurno ◽

...

Keyword(s):

Colon Carcinoma ◽

Small Molecule ◽

Hsp90 Inhibitor ◽

Carcinoma Cells ◽

Colon Carcinoma Cells ◽

Molecule Inhibitor ◽

Induced Apoptosis

Faculty Opinions recommendation of Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021658.247635 ◽

2004 ◽

Author(s):

William Kaelin

Keyword(s):

Small Molecule ◽

Shh Pathway ◽

Faculty Opinions recommendation of Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025625.322882 ◽

2005 ◽

Author(s):

James Stivers

Keyword(s):

Small Molecule ◽

Atm Kinase ◽

Molecule Inhibitor ◽

Hiv 1

Faculty Opinions recommendation of Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1033159.375732 ◽

2006 ◽

Author(s):

Berl R Oakley

Keyword(s):

Small Molecule ◽

Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1066069.520680 ◽

2007 ◽

Author(s):

Nathanael Gray

Keyword(s):

Small Molecule ◽

Molecule Inhibitor ◽

Bi 2536

Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1066069.519039 ◽

2007 ◽

Author(s):

Tarun Kapoor

Keyword(s):

Small Molecule ◽

Molecule Inhibitor ◽

Bi 2536

Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1283961.751061 ◽

2009 ◽

Author(s):

Marie-France Carlier

Keyword(s):

Small Molecule ◽

Identification And Characterization

Actin Assembly ◽

Molecule Inhibitor ◽

Faculty Opinions recommendation of Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5059957.4994055 ◽

2010 ◽

Author(s):

Michael Weber ◽

Daniel G Gioeli

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Amino Terminus ◽

Recurrent Prostate Cancer ◽