scholarly journals Assessment of the Effectiveness of Obstructive Sleep Apnea Treatment Using Optical Coherence Tomography to Evaluate Retinal Findings

2021 ◽  
Author(s):  
Gloria Tejero-Garcés ◽  
Francisco J Ascaso ◽  
Paula Casas ◽  
Maria I Adiego ◽  
Peter Baptista ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Optical Coherence Tomography ◽  
Sleep Apnea ◽  
Retinal Thickness ◽  
Sleep Apnea Syndrome ◽  
University Hospital ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Obstructive Sleep ◽  
Prospective Comparative Study

Retinal findings may change in patients with obstructive sleep apnea syndrome (OSAS). The present study aims to evaluate several retinal findings such as macula layer thickness, peripapillary retinal nerve fiber layer, and the optic nerve head in patients with OSAS using optical coherence tomography (OCT) and monitor the result of several types of treatment of OSAS with OCT. A prospective comparative study was designed. Patients were recruited at a Sleep Unit of a University Hospital and underwent comprehensive ophthalmological examinations. Following exclusion criteria, fifty-two patients with OSAS were finally included. Patients were examined by OCT twice: first, before treatment; secondly, after six months of treatment. In mild-moderate patients, where retinal swelling has been demonstrated, retinal thicknesses decreased [fovea (p=0.026), as well as inner ring macula (p=0.007), outer ring macula (p=0.015), and macular volume (p=0.015)]. In severe patients, where retinal atrophy had been observed, retinal thickness increased [fovea (p<0.001)]. No statistically significant differences in efficacy between treatments were demonstrated. In conclusion, OCT can evaluate the retina in patients with OSAS and help monitor results after treatment. In severe OSAS, retinal thickness increased six months after treatment.

Response to letter to editor “Optical coherence tomography (OCT) findings in obstructive sleep apnea” by Piotr Kanclerz

2018 ◽  
Vol 42 ◽  
pp. 232-233
Author(s):  
Marielle Mentek ◽  
Florent Aptel ◽  
Diane Godin-Ribuot ◽  
Renaud Tamisier ◽  
Jean-Louis Pepin ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Optical Coherence Tomography ◽  
Sleep Apnea ◽  
Optical Coherence ◽  
Obstructive Sleep

scholarly journals Retinal Nerve Fiber Layer, Ganglion Cell Complex and Choroidal Thickness Evaluation in Patients with Obstructive Sleep Apnea Syndrome

2021 ◽  
Author(s):  
Ela Eren ◽  
Nilufer Ilhan ◽  
Sebahat Genc
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Apnea Syndrome ◽  
Control Group ◽  
Ganglion Cell Complex ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Obstructive Sleep ◽  
The Mean ◽  
Apnea Syndrome

Abstract Purpose To evaluate the association of Obstructive Sleep Apnea Syndrome (OSAS) with Retinal Nerve Fiber Layer (RNFL), Ganglion Cell Complex (GCC) and choroidal tissue thickness (CCT). Methods: This cross-sectional study included 50 patients with OSAS and 50 controls between July 2014-January 2015). OSAS severity was classified by using the apnea-hypopnea index (AHI). RNFL thickness, GCC thickness and CCT analyses were performed by optic coherence tomography (OCT). Statistical analysis was performed using SPSS for Windows version 21 software. Results: The mean intraocular pressure (IOP) of the patients with OSAS 16.1±1.37, the cup/disc (C/D) ratio was 0.45±0.17 and vertical C/D ratio was 0.43±0.16. The control group mean IOP was 15.2±1.03, the C/D ratio was 0.36±0.20 and vertical C/D ratio was 0.34±0.19. These are all important measurements in glaucome and statisticallay significant (p=0.00, 0.022, 0.012). Althought the differences between the mean values of all quadrants RNFL thickness were similarly lower in OSAS group, this significance was not statistically different. Similarly the average GCC, minimum GCC and subfoveal CCT values between groups were not significant (p=0.79, 0.53, 0.9).Conclusion: In summary we found that peripapillary RNFL, GCC, CCT did not change with OSAS patients or the severity of OSAS. Further more we found that IOP, C/D ratio and vertical C/D ratio of patients were all significantly higher than control group. However multicenter longterm cohort studies are still needed to assess the definite changes of RNFL thickness, GCC and CCT in OSAS patients.

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