Laparoscopic Small Bowel Resection And Anastmosis For Small Proximal Jejunal Gastrointestinal Stromal Tumor Presented With Acute Massive Lower Gastrointestinal Bleeding: Case report and Literature review

2020 ◽  
Author(s):  
khaled S ahmad ◽  
Mohamed S Essa ◽  
Naif A Alenazi
Keyword(s):  
Small Bowel ◽  
Gastrointestinal Bleeding ◽  
Bowel Resection ◽  
Small Bowel Resection ◽  
Gi Bleeding ◽  
Case Presentation ◽  
Pressure Necrosis ◽  
Lower Gi Bleeding ◽  
Small Intestinal ◽  
Work Up

Abstract Background Gastrointestinal stromal tumors (GISTs) is the most common primary nonepithelial neoplasms of the gastointestinal tract, mostly expressing the KIT protein determined by immunohistochemical staining for the CD117 antigen. Jejunal GISTs represent approximately 10% of all GISTs. Abdominal discomfort is the usual presentation. Jejunal GISTs may present with complications such as intestinal obstruction or hemorrhage. Gastrointestinal bleeding occurs due to pressure necrosis and ulceration of overlying mucosa, and patients who develop significant bleeding may suffer from fatigue and malaise. Small-bowel GISTs are classified based on size, and several guidelines have recommended conservative treatment for small jejunal GISTs (<2 cm).Case presentation In this report, we describe a 35-year-old male, with a jejunal GIST, who presented with an unusual massive lower GI bleeding. After resuscitation extensive work up, he was taken finally for a diagnostic laparoscopy and resection of the mass.Conclusion Small intestinal GISTs are rare and unusual to present with massive lower GI bleeding.

Late Gastrointestinal Bleeding and Protein Loss after Distal Small-Bowel Resection in Infancy

1989 ◽  
Vol 9 (4) ◽  
pp. 454-460 ◽  
Author(s):  
R. T. L. Couper ◽  
P. R. Durie ◽  
S. E. Stafford ◽  
R. M. Filler ◽  
M. A. Marcon ◽  
...  
Keyword(s):  
Small Bowel ◽  
Gastrointestinal Bleeding ◽  
Bowel Resection ◽  
Small Bowel Resection ◽  
Protein Loss ◽  
Distal Small Bowel

scholarly journals Novel goblet cell gene related to IgGFcγBP is regulated in adapting gut after small bowel resection

2000 ◽  
Vol 279 (5) ◽  
pp. G1003-G1010 ◽  
Author(s):  
Deborah C. Rubin ◽  
Elzbieta A. Swietlicki ◽  
Hristo Iordanov ◽  
Christine Fritsch ◽  
Marc S. Levin
Keyword(s):  
Small Bowel ◽  
Bowel Resection ◽  
Intestinal Resection ◽  
Small Bowel Resection ◽  
Molecular Regulation ◽  
Mrna Levels ◽  
Small Intestinal ◽  
Cell Gene ◽  
Rat Gut

The loss of functional small bowel surface area leads to a well-described adaptive response in the remnant intestine. To elucidate its molecular regulation, a cohort of cDNAs were cloned using a rat gut resection model and subtractive/differential hybridization cloning techniques. This study reports a novel cDNA termed “ileal remnant repressed” (IRR)-219, which shares 80% nucleotide identity with the 3′end of a human intestinal IgG Fc binding protein (IgGFcγBP) and is homologous to human and rat mucins. IRR-219 mRNA is expressed in intestine and colon only. At 48 h after 70% intestinal resection, mRNA levels decreased two- to fivefold in the adaptive small bowel but increased two- to threefold in the colon. Expression of IRR-219 was suppressed in adaptive small bowel as late as 1 wk after resection. IRR-219 expression is also regulated during gut ontogeny. In situ hybridization revealed IRR-219 expression in small intestinal and colonic goblet cells only. Its unique patterns of expression during ontogeny and after small bowel resection suggest distinctive roles in small bowel and colonic adaptation.

Sodium-dependent D-glucose transport after proximal small intestinal resection in rat

1988 ◽  
Vol 255 (3) ◽  
pp. G292-G297 ◽  
Author(s):  
H. J. Freeman ◽  
S. T. Ellis ◽  
G. A. Johnston ◽  
W. C. Kwan ◽  
G. A. Quamme
Keyword(s):  
Small Bowel ◽  
Glucose Transport ◽  
Brush Border ◽  
Brush Border Membrane ◽  
Bowel Resection ◽  
Intestinal Resection ◽  
Small Bowel Resection ◽  
Proximal Small Bowel ◽  
Sodium Dependent ◽  
Small Intestinal

Massive small intestinal resection results in both structural and functional changes in the residual small bowel. Sodium-dependent D-glucose transport was examined in brush-border membrane vesicles derived from the terminal 20-30 cm of ileal mucosa of male Sprague-Dawley rats, 2 and 6 wk after 66% proximal jejunoileal resection or jejunoileal transection. Kinetic characteristics for sodium-dependent D-glucose transport were investigated with rapid filtration under conditions of a zero-trans, 100 mM cis-NaSCN gradient. Mucosal weight, protein, and DNA content were increased in the residual terminal intestinal segment compared with transected controls, whereas morphometric studies revealed increased villus and crypt heights as well as an increased mitotic index. Mean kinetic transport parameters at 6 wk after proximal small bowel resection revealed two saturable systems in the distal residual ileum: first, a low-affinity, high-capacity system with a Km of 0.19 +/- 0.03 mM and a Vmax of 0.48 +/- 0.04 nmol.mg protein-1.min-1; and second, a high-affinity, low-capacity system with a Km of 0.009 +/- 0.001 mM and a Vmax of 0.105 +/- 0.016 nmol.mg protein-1.min-1. In contrast, negligible sodium-dependent D-glucose transport was detected in the most distal ileum in control animals or animals 2 wk after resection or 2 and 6 wk after transection. Thus adaptational changes including mucosal hyperplasia and the appearance of two sodium-dependent D-glucose brush-border membrane vesicle transport systems occur in the residual distal intestine after massive proximal small bowel resection.

Laparoscopic-Assisted Small Bowel Resection of a Leiomyoma Causing Recurrent Obscure Gastrointestinal Bleeding

2005 ◽  
Vol 15 (4) ◽  
pp. 396-399 ◽  
Author(s):  
Konstantinos Konstantinidis ◽  
George E. Theodoropoulos ◽  
George Spanomihos ◽  
George Sambalis ◽  
Michael Vorias ◽  
...  
Keyword(s):  
Small Bowel ◽  
Gastrointestinal Bleeding ◽  
Bowel Resection ◽  
Small Bowel Resection ◽  
Obscure Gastrointestinal Bleeding ◽  
Laparoscopic Assisted

scholarly journals Arteriovenous Fistula of Superior Mesenteric Artery: An Unusual Cause of an Massive Lower Gastrointestinal Bleeding

2019 ◽  
Vol 104 (9-10) ◽  
pp. 499-501
Author(s):  
Yang Yang ◽  
Qisheng Ran ◽  
Dongfeng Chen
Keyword(s):  
Gastrointestinal Bleeding ◽  
Superior Mesenteric Artery ◽  
Arteriovenous Fistula ◽  
Mesenteric Artery ◽  
Right Hemicolectomy ◽  
Lower Gastrointestinal Bleeding ◽  
Gi Bleeding ◽  
Case Presentation ◽  
Common Causes ◽  
Lower Gi Bleeding

Introduction The most common causes of lower gastrointestinal (GI) hemorrhage are diverticulosis and angiodysplasia. Arteriovenous fistula (AVF) of the intestine is an uncommon cause of GI hemorrhage. Case Presentation Herein, we report a case of an embolization of an AVF originated from the superior mesenteric artery and vein as a cause of acute massive lower GI bleeding. Conclusion The patient underwent a right hemicolectomy and ileotransversostomy.

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