scholarly journals Single-Incision Port Robot-Assisted Surgery for Thymic Carcinoid Tumor Resection

2021 ◽  
Author(s):  
HIROAKI SHIDEI ◽  
Shota Mitsuboshi ◽  
Tomoko Yamamoto ◽  
Masato Kanzaki
Keyword(s):  
Carcinoid Tumor ◽  
Multiple Endocrine Neoplasia ◽  
Mediastinal Mass ◽  
Single Incision ◽  
Anterior Mediastinal Mass ◽  
Thymic Carcinoid ◽  
Men 1 ◽  
Endocrine Neoplasia ◽  
Thymic Carcinoid Tumor

Abstract Background: Multiple endocrine neoplasia (MEN) is divided into MEN type 1 (MEN-1) and MEN type 2 (MEN-2). MEN-1 may be associated with thymic carcinoid tumors. We present a case of the surgical removal of a thymic carcinoid associated with MEN-1 via a single-incision port RATS.Case presentation: A 39-year-old male patient with multiple endocrine neoplasia type 1 (MEN-1) who had an anterior mediastinal mass was referred to our hospital. The patient had undergone total parathyroidectomy and auto-transplantation of a partial parathyroid for hyperparathyroidism 6 years ago. Chest computed tomography revealed an isolated anterior mediastinal mass on the thymic gland with a maximum diameter measuring 22 mm. Thymic carcinoid tumor is classified as MEN-1 and has a poor prognosis, so we decided to remove the tumor. Single-incision port RATS was performed, and thymic carcinoid was confirmed in pathology.Conclusions: This report demonstrates that thymic carcinoid tumor removal is feasible and easy to perform via single-incision port RATS.

scholarly journals A rare case of multiple endocrine neoplasia type 1 initially presenting as an asymptomatic, huge mediastinal mass: case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ji Eun Jun ◽  
You-Cheol Hwang ◽  
Kyu Jeong Ahn ◽  
Ho Yeon Chung ◽  
In-Kyung Jeong
Keyword(s):  
Carcinoid Tumor ◽  
Rare Case ◽  
Multiple Endocrine Neoplasia ◽  
Mediastinal Mass ◽  
Multiple Endocrine Neoplasia Type ◽  
Thymic Carcinoid ◽  
Endocrine Glands ◽  
Endocrine Neoplasia ◽  
Thymic Carcinoid Tumor

Abstract Background Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited syndrome that concurrently involves various endocrine glands. We report a rare case of MEN1 in a 43-year-old man whose first manifestation was an asymptomatic mediastinal mass. Case presentation A 13-cm-sized mediastinal mass was diagnosed as an atypical thymic carcinoid by computed tomography and percutaneous needle biopsy. In addition, hypercalcemia from a left inferior parathyroid hyperplasia, and a non-functioning gastric neuroendocrine tumor seen on esophagogastroduodenoscopy were found. Therefore, the patient was clinically diagnosed with MEN1 syndrome, and underwent surgical resection of thymic carcinoid tumor after pre-operative concurrent chemoradiation therapy to decrease tumor size and volume. Parathyroid lesion and gastric neuroendocrine tumor were also removed. Finally, a MEN1 gene mutation was observed in the patient and his 7-year-old son. Conclusion Despite its rare occurrence, thymic carcinoid tumor should be considered as a MEN1-associated tumor and necessitates screening of other endocrine glands. Thymic carcinoid tumor carries a poor prognosis in patients with MEN1, and thus it needs to be carefully monitored even after radical excision.

Cushing's Syndrome Secondary to a Thymic Carcinoid Tumor Due to Multiple Endocrine Neoplasia Type 1

2011 ◽  
Vol 1 (-1) ◽  
pp. 1-16
Author(s):  
Ali A Ghazi ◽  
Azizollah Abbasi Dezfooli ◽  
Farzaneh Mohamadi ◽  
Seyed Vahid Yousefi ◽  
Alireza Amirbaigloo ◽  
...  
Keyword(s):  
Carcinoid Tumor ◽  
Cushing’S Syndrome ◽  
Multiple Endocrine Neoplasia ◽  
Multiple Endocrine Neoplasia Type ◽  
Cushing's Syndrome ◽  
Thymic Carcinoid ◽  
Endocrine Neoplasia ◽  
Endocrine Neoplasia Type ◽  
Thymic Carcinoid Tumor

Cushing Syndrome Secondary to a Thymic Carcinoid Tumor Due to Multiple Endocrine Neoplasia Type 1

2011 ◽  
Vol 17 (4) ◽  
pp. e92-e96 ◽  
Author(s):  
Ali Ghazi ◽  
Azizollah Dezfooli ◽  
Farzaneh Mohamadi ◽  
Seyed Yousefi ◽  
Alireza Amirbaigloo ◽  
...  
Keyword(s):  
Carcinoid Tumor ◽  
Multiple Endocrine Neoplasia ◽  
Multiple Endocrine Neoplasia Type ◽  
Cushing Syndrome ◽  
Thymic Carcinoid ◽  
Endocrine Neoplasia ◽  
Endocrine Neoplasia Type ◽  
Thymic Carcinoid Tumor

scholarly journals A case of recurrent thymic carcinoid tumor with multiple endocrine neoplasia syndrome.

2001 ◽  
Vol 62 (3) ◽  
pp. 638-642
Author(s):  
Yoshinobu HATA ◽  
Shin-ichi MATSUOKA ◽  
Nobuhisa NAKAJIMA ◽  
Keiko MAKITA ◽  
Ryoichi YOKOTA ◽  
...  
Keyword(s):  
Carcinoid Tumor ◽  
Multiple Endocrine Neoplasia ◽  
Thymic Carcinoid ◽  
Endocrine Neoplasia ◽  
Thymic Carcinoid Tumor ◽  
Multiple Endocrine Neoplasia Syndrome

Challenges in the differential diagnosis of multiple endocrine neoplasia syndrome type 1 with isolated family hyperparathyroidism

2020 ◽  
Vol 98 (3) ◽  
pp. 218-225
Author(s):  
J. A. Krupinova ◽  
N. G. Mokrysheva ◽  
N. Y. Kalinchenko ◽  
A. K. Eremkina ◽  
A. N. Polyakov ◽  
...  
Keyword(s):  
Multiple Endocrine Neoplasia ◽  
Molecular Genetic ◽  
Pancreatic Neuroendocrine Tumor ◽  
Family Type ◽  
Dynamic Monitoring ◽  
Heterozygous Mutation ◽  
Molecular Genetic Study ◽  
Men 1 ◽  
Endocrine Neoplasia

Multiple endocrine neoplasia type 1 (MEN-1) is the most common cause of the hereditary type of primary hyperparathyroidism (PHPT). If a family type of PHPT is suspected, a dynamic monitoring of patients and their close relatives should be carried out throughout their lives. We present a clinical case of a family in which four members of a pedigree were diagnosed with familial isolated hyperparathyroidism (FIHP). The diagnosis was changed to MEN-1, because it appeared that one of the patients had pancreatic neuroendocrine tumor. Molecular genetic study of MEN1 by direct by means of Sanger sequencing revealed that six family members had a new heterozygous mutation in exon 9: s. 1252 G> T p. D418Y.

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