scholarly journals Free flap transfer, a safe and efficient method for reconstruction of composite skull base defects after salvage resection of advanced intra- and extracranial communicating tumors

Author(s):  
Hou jie Liu ◽  
Xue-Ji Li ◽  
Hai-Peng Qian ◽  
Chang-Ming An ◽  
De-Zhi Li ◽  
...  

Abstract Propose: Surgical treatment of advanced intra- and extracranial communicating skull base tumors is challenging, especially for the reconstruction of the large composite defect left by tumor resection. The aim of the study is to evaluate the utility of the free flap reconstruction of the defects resulting from radical resection of these tumors. Methods: The clinical data of 17 consecutive patients who underwent free flap reconstruction for defect left by salvage resection of advanced intra- and extracranial communicating tumors from 2013 to 2019 were retrospectively collected and analyzed. Results: There were 5 squamous cell carcinomas, 4 adenoid cystic carcinomas, 2 basal cell carcinomas, 2 meningiomas, 1 anaplastic hemangiopericytoma, 1 pleomorphic adenoma, 1 osteosarcoma and 1 chondrosarcoma. All patients had recurrent neoplasms, 2 of which had pulmonary metastasis. A modified radical cervical dissection was performed in 6 patients. The anterolateral thigh flap myocutaneous (ALT) flap and rectus abdominis myocutaneous (RAM) flap were used in 15 patients (88.2%) and 2 patients (11.8%), respectively. Complications were seen in 3 of 17 patients (17.6%) with 1 total flap loss. The median PFS duration was 31 months. The 3- and 5-year PFS rate was 0.47 and 0.24, respectively. The mean OS duration was 66 months. The 3- and 5-year OS rate was 0.85 and 0.68, respectively. Conclusion: Free flap transfer is a safe and effective method with acceptable complications, useful for reconstruction of large composite skull base defects after salvage resection of advanced intra- and extracranial communicating tumors. The functional and cosmetic results are satisfying.

2012 ◽  
Vol 147 (2_suppl) ◽  
pp. P158-P159
Author(s):  
Sally M. Kamal ◽  
Andrew Cho ◽  
Joel P. Jacobson ◽  
Kiarash Shahlaie ◽  
Quang C. Luu

2019 ◽  
Vol 33 (01) ◽  
pp. 030-037 ◽  
Author(s):  
Aurora Vincent ◽  
Jason Burkes ◽  
Fayette Williams ◽  
Yadranko Ducic

AbstractTumors of the maxilla and midface are some of the most difficult to manage, not only in terms of treatment but also in terms of achieving acceptable orofacial reconstruction. Today, free flaps dominate the reconstructive field. Many patients can achieve successful reconstruction after free flap transfer with a return of intelligible speech, a regular diet, and acceptable cosmesis. Herein, the authors review free flap reconstruction of the maxilla, with a focus on the classifications of defects, when obturators are appropriate, types and sources of free flaps, and complications for which to beware.


2012 ◽  
Vol 40 (2) ◽  
pp. 177-179 ◽  
Author(s):  
Angélique Girod ◽  
Herve Boissonnet ◽  
Thomas Jouffroy ◽  
José Rodriguez

2020 ◽  
Author(s):  
Sen J. Ninan ◽  
Katherine Liu ◽  
Todd Spock ◽  
Eric Lee ◽  
Andrey Filimonov ◽  
...  

Author(s):  
Rajan P. Dang ◽  
Lauren T. Roland ◽  
Jeffrey D. Sharon ◽  
Michelle Doering ◽  
Michael R. Chicoine ◽  
...  

Introduction Microvascular free flaps offer an alternative to local and regional flaps for coverage of complex or large skull base defects. Routes and approaches to these reconstructive options are complicated and require an understanding of complex head and neck anatomy. Methods A systematic review of the literature was performed using a set of search terms with the help of a qualified librarian. Articles were reviewed and selected for inclusion based on relevance. We were interested in reporting possible routes for free flap accessibility to the skull base as well as microvascular vessel options, as this choice may affect the geometry and accessibility to the defect. Results A total of 1,917 articles were obtained from a comprehensive search and 11 articles were ultimately found to be relevant to this review. Published options for vessel anastomosis and corridors to the skull base following endoscopic endonasal surgery are reviewed, including Caldwell-Luc/transbuccal space, prevertebral space, transpterygoid/parapharyngeal, and transmaxillary approaches. Conclusion The field of endoscopic surgery has continued to advance and provide options for tumors of the skull base. This has led to a need for creative routes to the skull base for free flap reconstruction.


1989 ◽  
Vol 14 (1) ◽  
pp. 45-46 ◽  
Author(s):  
H. Nettelblad ◽  
L-E. Karlander ◽  
G. Nylander

A free flap transfer in a case of Adriamycin necrosis on the dorsum of the hand is reported. The advantages of this method of reconstruction are discussed.


Author(s):  
Rajan P. Dang ◽  
Abhinav R. Ettyreddy ◽  
Zain Rizvi ◽  
Michelle Doering ◽  
Angela L. Mazul ◽  
...  

Abstract Objectives Given the limitations in the available literature, the precise indications, techniques, and outcomes of anterior skull base free flap reconstruction remain uncertain. The objective of this study was to perform a systematic review of published literature and evaluate indications, methods, and complications for anterior skull base free flap reconstruction. Methods A systematic review of the literature was performed using a set of search criteria to identify patients who underwent free flap reconstruction of the anterior skull base. Articles were reviewed for inclusion based on relevance, with the primary outcome being surgical complications. Results After a comprehensive search, 406 articles were obtained and 16 articles were ultimately found to be relevant to this review—79 patients undergoing free flap reconstruction were identified. Overall complication rates were 17.7% (95% confidence interval [CI]: 16.6–33.1%) for major complications and 19.0% (95% CI: 17.8–35.5%) for minor complications. Conclusion Microvascular reconstruction of the anterior skull base is feasible with high reliability reported in the literature.


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