Efficacy of a Novel Large-cell Niti-S stent with a Slim Delivery System for Hilar Biliary Obstruction: A Preliminary Study
Abstract Background: The large-cell Niti-S stent is useful for multiple stenting in malignant hilar biliary obstruction (MHBO) patients. Recently, a novel uncovered self-expandable metallic stent (USEMS) (a large-cell Niti-S slim-delivery stent) was developed. In this study, we aimed to evaluate the efficacy of this slim-delivery USEMS in MHBO patients.Methods: Outcomes related to USEMS placement, clinical course, and patency period were evaluated in MHBO patients who received multiple USEMSs.Results: Fourteen MHBO patients underwent the placement of multiple USEMSs, including using the novel slim-delivery stent. Three patients had a past history of Billroth-II reconstruction. The number of USEMSs placed in each patient was 2-6. Three procedures were reinterventions. The new slim delivery system was used to place the first stent in three patients and an additional stent in the remaining patients. The technical and clinical success rates were both 100%. According to Kaplan-Meier analysis, the cumulative patency rate 50 days after USEMS placement was 87.5%.Conclusions: Placing multiple USEMSs in patients with a past history of abdominal surgery or in reintervention is difficult. The novel USEMS might overcome these difficulties and be the first choice for MHBO patients. TRIAL REGISTRATION: Not applicable