scholarly journals Long-term Survival of Patients With Unoperated Single Ventricle Heart Defect: Four Case Reports and Literature Review

Author(s):  
Shengnan Zhao ◽  
Jiantao Guo ◽  
Zhixia Sun ◽  
Tingting Cui

Abstract Background: A single ventricle heart defect is a rare complex congenital cardiac malformation. It is rare for patients with single ventricle to spontaneously survive long-term to adulthood. No literature was retrieved that summarized the ultrasonographic features of patients with single ventricle who survived for a long time without surgery.Case presentation: Four patients in this study were diagnosed with single ventricle heart defects during childhood, but received no surgical intervention. All four patients had good outcomes. We summarize the ultrasound findings of these patients.Conclusion: We summarize the factors that contribute to the long-term survival of single ventricle patients without surgical intervention, and discuss the diagnosis and treatment of single ventricle to improve the survival rate of patients.

Author(s):  
Shengnan Zhao ◽  
Jiantao Guo ◽  
Zhixia Sun ◽  
Tingting Cui

A single ventricle (SV) heart defect is a rare complex congenital cardiac malformation. We followed up the four adult patients who had SV since birth without surgical intervention and they had a good prognosis.The common ultrasound characteristics of four long-term SV survivors were investigated by reviewing their medical records and the literature, and the current treatment methods for SV patients were also reviewed. In our opinion,such patients with balanced hemodynamic condition should be followed and treated conservatively. This report aims to improve the prognosis as well as quality of life of SV patients.


2020 ◽  
Vol 72 (2) ◽  
pp. 480-489
Author(s):  
Nathan J. Aranson ◽  
Priya B. Patel ◽  
Jahan Mohebali ◽  
Robert T. Lancaster ◽  
Emel A. Ergul ◽  
...  

Cancer ◽  
1979 ◽  
Vol 43 (2) ◽  
pp. 730-734 ◽  
Author(s):  
Merrill S. Kies ◽  
Dan W. Luedke ◽  
James F. Boyd ◽  
Miles J. McCue

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Ying-Tso Chen ◽  
Shu-Shong Hsu ◽  
Chi-Man Yip ◽  
Ping-Hong Lai ◽  
Huai-Pao Lee

Introduction. Glioblastoma multiforme (GBM), the most common primary malignant brain tumor in adults, is characterized by extensive heterogeneity in its clinicopathological presentation. A primary brain tumor with both astrocytic differentiation and neuronal immunophenotype features is rare. Here, we report a long-term survival patient who presented this rare form of GBM in the disease course. Presentation of Case. A 23-year-old woman, presenting with rapidly progressive headache and right-side weakness, was diagnosed with brain tumor over the left basal ganglion. She underwent the first craniectomy for tumor removal, and histopathology revealed classic GBM. Tumor recurrence occurred 8 years later. Another gross total resection was performed and pathology revealed GBM with the oligodendroglioma component (GBM-O). Due to disease progression, she received debulking surgery the following year. The third pathology revealed glioblastoma with primitive neuroectodermal tumor-like component (GBM-PNET). Discussion. GBM-PNETs are collision tumors with both neuronal and glial components. They are rare, and a few case reports have suggested that these tumors are associated with favorable outcomes but a higher risk of cerebrospinal fluid dissemination. Conclusion. We report a patient who developed the distinct pathologic variants of classic GBM, GBM-O, and GBM-PNET, throughout the disease course. Young age, aggressive surgical resection, and pathologic and genetic features may have contributed to the long-term survival of the patient.


2013 ◽  
Vol 32 (9) ◽  
pp. 735-736
Author(s):  
Manuel Barreiro ◽  
Cecília Corros ◽  
Laura García ◽  
Alfredo Renilla ◽  
María Martin ◽  
...  

2015 ◽  
Vol 62 (4) ◽  
pp. 1094
Author(s):  
Nathan J. Aranson ◽  
Virendra I. Patel ◽  
Christopher A. Durham ◽  
Mark F. Conrad ◽  
R. Todd Lancaster ◽  
...  

2007 ◽  
Vol 94 (4) ◽  
pp. 438-443 ◽  
Author(s):  
Leif Eskedal ◽  
Peter Skjalg Hagemo ◽  
Anne Eskild ◽  
Geir Aamodt ◽  
Kerry S Seiler ◽  
...  

2015 ◽  
Vol 26 (4) ◽  
pp. 805-807 ◽  
Author(s):  
Valentina Gesuete ◽  
Marianna Fabi ◽  
Marco Bonvicini

AbstractUniventricular heart is a rare congenital heart malformation. Nowadays prognosis is considered to be strictly linked to surgical intervention, and survival into late adulthood is unusual.In some patients native haemodynamic circulation balances pulmonary and systemic blood flow, allowing long-term survival without the need for surgery.We report the case of a 74-year-old man with a univentricular heart in natural history, and we discuss the factors that might contribute to his extraordinary long-term survival.


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