scholarly journals Long-term survival of patients with unoperated single ventricle heart : case reports and literature review

Author(s):  
Shengnan Zhao ◽  
Jiantao Guo ◽  
Zhixia Sun ◽  
Tingting Cui

A single ventricle (SV) heart defect is a rare complex congenital cardiac malformation. We followed up the four adult patients who had SV since birth without surgical intervention and they had a good prognosis.The common ultrasound characteristics of four long-term SV survivors were investigated by reviewing their medical records and the literature, and the current treatment methods for SV patients were also reviewed. In our opinion,such patients with balanced hemodynamic condition should be followed and treated conservatively. This report aims to improve the prognosis as well as quality of life of SV patients.

2021 ◽  
Author(s):  
Shengnan Zhao ◽  
Jiantao Guo ◽  
Zhixia Sun ◽  
Tingting Cui

Abstract Background: A single ventricle heart defect is a rare complex congenital cardiac malformation. It is rare for patients with single ventricle to spontaneously survive long-term to adulthood. No literature was retrieved that summarized the ultrasonographic features of patients with single ventricle who survived for a long time without surgery.Case presentation: Four patients in this study were diagnosed with single ventricle heart defects during childhood, but received no surgical intervention. All four patients had good outcomes. We summarize the ultrasound findings of these patients.Conclusion: We summarize the factors that contribute to the long-term survival of single ventricle patients without surgical intervention, and discuss the diagnosis and treatment of single ventricle to improve the survival rate of patients.


2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Lara Devilli ◽  
Chiara Garonzi ◽  
Rita Balter ◽  
Elisa Bonetti ◽  
Matteo Chinello ◽  
...  

Long-term survival for acute lymphoblastic leukemia (ALL) in children improved over the last three decades up to 80-90% of affected patients. Consequently, the quality of life of survivors has become increasingly important. This study analyses the clinical features and outcome of 119 children with ALL, focusing on the quality of long-term survival in a subset of 22 patients over 18 years of age. Among this group, the 10-year event-free survival and overall survival were 83.1% (C.I. 74.0-89.2) and 88.4% (C.I. 80.9-93.1), respectively. Treatment related long-term medical complications were reported only in 2 patients (9.1%). Secondary school was completed successfully in 20 of 22 patients (89.9%). The remaining 2 patients were still attending at the time of the analysis. In conclusion, current treatment for ALL is well tolerated and does not compromise significantly the quality of life of survivors.


2018 ◽  
Vol 36 (1) ◽  
pp. 33-36
Author(s):  
Md Nazmul Hasan ◽  
Md Abu Siddique ◽  
Sajal Krishna Banerjee ◽  
Abu Sadique Abdullah

Coarctation of the aorta is a congenital cardiac malformation that can go undiagnosed until old age with only hypertension as a marker of its presence because clinical signs can be subtle and overlooked if a complete physical exam is not performed. Long-term survival is exceptional in patients with untreated aortic coarctation. In this case report, we present a late diagnosis of aortic coarctation in a 45-year-old male. Our patient was relatively asymptomatic until he presented with exertional dyspnea and fatigue in his fourth decade of life. The patient was managed by surgery of aorta. After the 6 months follow-up visit, the patient was in good clinical condition.J Bangladesh Coll Phys Surg 2018; 36(1): 33-36


2020 ◽  
Vol 72 (2) ◽  
pp. 480-489
Author(s):  
Nathan J. Aranson ◽  
Priya B. Patel ◽  
Jahan Mohebali ◽  
Robert T. Lancaster ◽  
Emel A. Ergul ◽  
...  

CHEST Journal ◽  
2010 ◽  
Vol 137 (4) ◽  
pp. 783-789 ◽  
Author(s):  
Guangxi Li ◽  
Marija Kojicic ◽  
Martin K. Reriani ◽  
Evans R. Fernández Pérez ◽  
Lokendra Thakur ◽  
...  

Cancer ◽  
1979 ◽  
Vol 43 (2) ◽  
pp. 730-734 ◽  
Author(s):  
Merrill S. Kies ◽  
Dan W. Luedke ◽  
James F. Boyd ◽  
Miles J. McCue

2006 ◽  
Vol 23 (Supplement 38) ◽  
pp. 22
Author(s):  
E. Bignami ◽  
G. Landoni ◽  
G. Crescenzi ◽  
G. Giardina ◽  
F. Boroli ◽  
...  

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