scholarly journals Clinical utility of esomeprazole for treatment of gastroesophageal reflux disease in pediatric and adolescent patients

2012 ◽  
pp. 27 ◽  
Author(s):  
Claudio Romano ◽  
Cardile
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Clinical Utility ◽  
Adolescent Patients

Pharmacokinetics of lansoprazole in adolescent patients with gastroesophageal reflux disease (GERD)

2000 ◽  
Vol 118 (4) ◽  
pp. A1241 ◽  
Author(s):  
Thirumazhisai Gunasekaran ◽  
Wei-Jian Pan ◽  
Ramon Torres-Pinedo ◽  
Linda Book ◽  
David Gremse ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Adolescent Patients

Adolescent patients with gastroesophageal reflux disease (GERD): Results from a randomized trial of lansoprazole

2000 ◽  
Vol 118 (4) ◽  
pp. A1242 ◽  
Author(s):  
Sandeep K. Gupta ◽  
Vasundhara K. Tolia ◽  
Melvin B. Heyman ◽  
Robert E. Kane ◽  
Yi-Lin Chiu ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Randomized Trial ◽  
Reflux Disease ◽  
Adolescent Patients

Single Isomer Versus Racemate: Is There a Difference? Clinical Comparisons in Allergy and Gastroenterology

CNS Spectrums ◽  
2002 ◽  
Vol 7 (S1) ◽  
pp. 23-27 ◽  
Author(s):  
David A. Flockhart ◽  
Harold S. Nelson
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Adverse Effects ◽  
Drug Interactions ◽  
Reflux Disease ◽  
Clinical Utility ◽  
Pharmacokinetic Profile ◽  
Peptic Ulcers ◽  
Receptor Affinity ◽  
Single Isomer

ABSTRACTMany commonly prescribed drugs exist as a mixture of two distinct chiral isomer forms (enantiomers), each with its own unique chemistry, receptor affinity, and pharmacokinetic profile. Much is unknown concerning the clinical utility of these single enantiomers. This review of the stereoisomers of two commonly used drugs—albuterol for asthma and omeprazole for gastroesophageal reflux disease (GERD) and peptic ulcers—examines the improved efficacy, pharmacokinetics, decreased adverse effects, and fewer drug-drug interactions associated with single enantiomers.

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