scholarly journals The current status of immunobased therapies for metastatic renal-cell carcinoma

2017 ◽  
Vol Volume 6 ◽  
pp. 83-93 ◽  
Author(s):  
Niranjan J Sathianathen ◽  
Suprita Krishna ◽  
J Kyle Anderson ◽  
Christopher J Weight ◽  
Shilpa Gupta ◽  
...  
Kidney Cancer ◽  
2017 ◽  
Vol 1 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Laure Fournier ◽  
Alexandre Bellucci ◽  
Yann Vano ◽  
Mehdi Bouaboula ◽  
Constance Thibault ◽  
...  

Drugs ◽  
2013 ◽  
Vol 73 (5) ◽  
pp. 427-438 ◽  
Author(s):  
Bernard Escudier ◽  
Laurence Albiges ◽  
Guru Sonpavde

2019 ◽  
Vol 26 (6) ◽  
pp. 608-617 ◽  
Author(s):  
Jun Teishima ◽  
Shogo Inoue ◽  
Tetsutaro Hayashi ◽  
Akio Matsubara

2012 ◽  
Vol 1 (2S) ◽  
Author(s):  
Anil K. Kapoor ◽  
Sébastien J. Hotte

Cytokine therapy with interferon-a and interleukin-2 has arguably been the standard treatment for patients with metastatic renal cell carcinoma for more than 20 years. In this paper, the current evidence for the use of cytokine therapy in this patient population is discussed, including the significant toxicity associated with these agents. A low overall response rate and a marginal survival advantage are observed with interferon-a and interleukin-2; however,these therapies have significant toxicity and impair quality of life. Unlike thecurrent tyrosine-kinase inhibitors, complete tumour responses may be seen with interleukin-2, but again this therapy has significant morbidity and mortality.Newer anti-angiogenesis agents may be combined with current standard cytokinetherapy for patients with metastatic renal cell carcinoma.


2007 ◽  
Vol 6 (10) ◽  
pp. 665-671 ◽  
Author(s):  
Pieter H.M. De Mulder ◽  
Jean-Jaques Patard ◽  
Cezary Szczylik ◽  
Thomas Otto ◽  
Tim Eisen

2013 ◽  
Vol 13 (6) ◽  
pp. 697-709 ◽  
Author(s):  
Matteo Santoni ◽  
Michele De Tursi ◽  
Alessandra Felici ◽  
Giovanni Lo Re ◽  
Riccardo Ricotta ◽  
...  

2012 ◽  
Vol 19 (4) ◽  
pp. 284-295 ◽  
Author(s):  
Yoshihiro Wada ◽  
Wataru Takahashi ◽  
Yoshiaki Kawano ◽  
Masatoshi Eto

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