<p>Evaluation of Salivary Gland Lesions by Fine Needle Aspiration Cytology at a Tertiary Care Hospital, Western Nepal</p>

Background: Multinodular goiter (MNG) occurs due to repeated hyperstimulation of thyroid gland due to iodine deficiency, goitrogens, antithyroid drugs and genetic defects. MNG can have different complications which include treacheal compression, retrosternal extension, malignancy and secondary thyrotoxicosis. The aim of the work was to study the clinical features and histopathology of MN in patients admitted for thyroidectomy in surgical wards of a tertiary care hospital in north Kerala.Methods: A prospective hospital based observational study in the patients in surgical wards of a tertiary care hospital in north Kerala from April 2011 to March 2012. The clinical data of patients who are subjected to thyroidectomy for MNG (clinical and fine needle aspiration cytology diagnosis) were included in this study. Patients undergoing completion thyroidectomy for recurrence or malignancy were excluded from this study.Results: MNG is more common in females. Female to male ratio 24:1 Majority are in the age group of 30-50 years (64%) with a mean age of 41 years. 38% (38 cases) had pressure symptoms in the form of dysphagia or dyspnea. Secondary thyrotoxicosis seen in 17% (17 cases). Fine needle aspiration cytology (FNAC) is not an error-proof investigation in MNG. 14 % of our patients had malignancy inspite of being reported as benign in FNAC. Among the malignancies papillary carcinoma thyroid was found to be most common accounting for 12% of cases (12/100) followed by follicular carcinoma.Conclusions: FNAC is not an error proof investigation in MNG. Incidental thyroid cancer in MNG is about 14 % with papillary carcinoma thyroid being the commonest.

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Correlation of fine needle aspiration cytology and histopathology in the diagnosis of salivary gland lesions in a tertiary care hospital in the Southern part of Assam: a 2 year observational study

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20195912 ◽

2019 ◽

Vol 8 (1) ◽

pp. 226

Author(s):

Musfika Tabassum ◽

Monoj Kumar Deka ◽

Nitu Mani Khakhlari

Keyword(s):

Salivary Gland ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Wide Spectrum ◽

Tertiary Care ◽

Needle Aspiration ◽

Care Hospital ◽

Aspiration Cytology ◽

Fine Needle ◽

Needle Aspiration Cytology

Background: Fine Needle Aspiration Cytology (FNAC) of the salivary gland is one of the most challenging in the field of cytopathology due to the wide spectrum of lesions. There is significant cytomorphologic diversity and overlap between many benign and malignant salivary gland tumours. Though FNAC is quite an effective tool for the diagnosis of salivary gland lesions, it has always been under scrutiny and histopathology continues to be the final method to establish a diagnosis.Methods: A total of 80 patients who presented with clinical diagnosis of salivary gland mass at the Department of Pathology, SMCH, Assam from August 2017 to August 2019 were included in the study. FNAC was performed in all the cases and the cytological findings were correlated with that of the histopathological findings (wherever possible).Results: The median age group of patients was in the range of 30-40 years (30%). 60 patients underwent surgical procedure and hence histopathological correlation could be done in these patients. Among the various diagnosis in FNAC, benign tumours constitute the majority with 36 cases (60%). The most commonly involved benign tumour was pleomorphic adenoma (27 cases). The overall sensitivity, specificity & diagnostic accuracy of FNAC were found to be 87.3%, 93.9% and 93.33% respectively.Conclusions: FNAC is a safe, reliable, time saving, cost-effective, convenient and accurate method and should be considered as one of the pivotal investigations in the evaluation of salivary gland lesions.

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