scholarly journals Treatment of severe sepsis: where next? Current and future treatment approaches after the introduction of drotrecogin alfa

2006 ◽  
Vol 2 (1) ◽  
pp. 3-18 ◽  
Author(s):  
Todd W Rice
Keyword(s):  
Severe Sepsis ◽  
Drotrecogin Alfa ◽  
Treatment Approaches ◽  
Future Treatment

Drotrecogin alfa (activated) inhibits NF-kappa B activation and MIP-1-alpha release from isolated mononuclear cells of patients with severe sepsis

2004 ◽  
Vol 53 (10) ◽  
pp. 528-533 ◽  
Author(s):  
M. Brueckmann ◽  
U. Hoffmann ◽  
E. Dvortsak ◽  
S. Lang ◽  
J. J. Kaden ◽  
...  
Keyword(s):  
Severe Sepsis ◽  
Drotrecogin Alfa ◽  
Mononuclear Cells ◽  
Nf Kappa B ◽  
Drotrecogin Alfa Activated

scholarly journals Use of an integrated clinical trial database to evaluate the effect of timing of drotrecogin alfa (activated) treatment in severe sepsis

Critical Care ◽  
2006 ◽  
Vol 10 (3) ◽  
Author(s):  
Jean-Louis Vincent ◽  
James O'Brien ◽  
Arthur Wheeler ◽  
Xavier Wittebole ◽  
Rekha Garg ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Severe Sepsis ◽  
Drotrecogin Alfa ◽  
Clinical Trial Database ◽  
Drotrecogin Alfa Activated

scholarly journals Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis

Critical Care ◽  
2008 ◽  
Vol 12 (5) ◽  
pp. R117 ◽  
Author(s):  
Pierre-François Laterre ◽  
William L Macias ◽  
Jonathan Janes ◽  
Mark D Williams ◽  
David R Nelson ◽  
...  
Keyword(s):  
Severe Sepsis ◽  
Drotrecogin Alfa ◽  
Sequence Effect ◽  
Drotrecogin Alfa Activated

scholarly journals The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis *

2004 ◽  
Vol 32 (11) ◽  
pp. 2199-2206 ◽  
Author(s):  
Derek C. Angus ◽  
Pierre-Francois Laterre ◽  
Jeff Helterbrand ◽  
E Wesley Ely ◽  
Daniel E. Ball ◽  
...  
Keyword(s):  
Severe Sepsis ◽  
Drotrecogin Alfa ◽  
Term Survival ◽  
Long Term Survival ◽  
Drotrecogin Alfa Activated
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