Od 2D do DIBH, przegląd technik radioterapeutycznych stosowanych w napromienianiu nowotworów piersi From 2D to DIBH, review of radiotherapeutic techniques related to irradiation of breast cancer

Nowotwór piersi jest to nowotwór złośliwy powstający z komórek gruczołu piersiowego, który rozwija się miejscowo w piersi oraz daje przerzuty do węzłów chłonnych i narządów wewnętrznych (płuc, wątroby, kości i mózgu). Ponad 23% zachorowań na nowotwory kobiet w Polsce, jak i na świecie stanowią nowotwory piersi. Na przestrzeni ostatnich lat techniki napromieniania nowotworów piersi ulegają ciągłemu rozwojowi. Celem pracy było poglądowe przedstawienie technik radioterapeutycznych stosowanych w napromienianiu nowotworów piersi, od dwuwymiarowej 2D techniki statycznej poprzez techniki dynamiczne (IMRT technika z modulacją intensywnością dawki (ang. intensity modulated radiation therapy), VMAT technika obrotowa z modulacją intensywności dawki (ang. volumetric modulated arc therapy), aż do techniki DIBH techniki napromieniania na głębokim wstrzymanym wdechu (ang. deep inspiration breath hold). W pracy skupiono się na przedstawieniu realizacji omawianych technik i opisie jak dana technika wpływa na rozkład dawki w planowanej objętości do napromieniania PTV (ang. Planning Target Volume) oraz na dawki w narządach krytycznych w radioterapii nowotworów piersi.

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Dosimestric comparison of hybrid volumetric-modulated arc therapy and hybrid intensity-modulated radiation therapy for left-sided breast cancer with or without voluntary deep inspiration breath hold control

10.5353/th_991044020097903414 ◽

2017 ◽

Author(s):

Man I Lei

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Volumetric Modulated Arc Therapy ◽

Intensity Modulated Radiation Therapy ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Intensity Modulated ◽

Arc Therapy

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Left-Sided Breast Cancer Locoregional Radiation Therapy With Deep Inspiration Breath Hold (DIBH): Does Volumetric Modulated Arc Therapy (VMAT) Reduce the Cardiac Dose Further When Compared to Tangential Intensity Modulated Radiation Therapy (T-IMRT)?

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2014.05.890 ◽

2014 ◽

Vol 90 (1) ◽

pp. S255

Author(s):

T.T. Pham ◽

R. Ward ◽

D. Latty ◽

C. Owen ◽

J. Sykes ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Volumetric Modulated Arc Therapy ◽

Intensity Modulated Radiation Therapy ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Intensity Modulated ◽

Cardiac Dose ◽

Arc Therapy

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Phase II Study of Deep Inspiration Breath Hold (DIBH) and Intensity Modulated Radiation Therapy (IMRT) Treatment for Women with Left-sided Breast Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2008.06.971 ◽

2008 ◽

Vol 72 (1) ◽

pp. S90 ◽

Cited By ~ 2

Author(s):

E.S. Wai ◽

D. Wells ◽

B. Bendorffe ◽

J. Runkel ◽

W. Beckham ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Phase Ii ◽

Phase Ii Study ◽

Intensity Modulated Radiation Therapy ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Intensity Modulated

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Proton Therapy of Localized Left Breast Cancer Improves Cardiac and Left Lung Sparing Compared to Intensity Modulated Radiation Therapy With or Without Deep Inspiration Breath Hold

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2016.06.743 ◽

2016 ◽

Vol 96 (2) ◽

pp. E60-E61

Author(s):

G. Noel ◽

N. Schreuder ◽

P. Meyer ◽

S.G. Price ◽

A.G. Meek ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Proton Therapy ◽

Left Lung ◽

Intensity Modulated Radiation Therapy ◽

Left Breast ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Intensity Modulated

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Dosimetric Benefit of Deep Inspiration Breath Hold (DIBH) and Intensity Modulated Radiation Therapy (IMRT) for Women with Left-sided Breast Cancer

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2008.06.022 ◽

2008 ◽

Vol 72 (1) ◽

pp. S513

Author(s):

D.M. Wells ◽

E.S. Wai ◽

B. Bendorffe ◽

W. Beckham ◽

C. Popescu ◽

...

Keyword(s):

Breast Cancer ◽

Radiation Therapy ◽

Intensity Modulated Radiation Therapy ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Intensity Modulated

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Effect of Deep Inspiration Breath Hold on Normal Tissue Sparing With Intensity Modulated Radiation Therapy Versus Proton Therapy for Mediastinal Lymphoma

Advances in Radiation Oncology ◽

10.1016/j.adro.2020.08.004 ◽

2020 ◽

Vol 5 (6) ◽

pp. 1255-1266

Author(s):

Amy C. Moreno ◽

Jillian R. Gunther ◽

Sarah Milgrom ◽

C. David Fuller ◽

Tyler Williamson ◽

...

Keyword(s):

Radiation Therapy ◽

Proton Therapy ◽

Normal Tissue ◽

Intensity Modulated Radiation Therapy ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Intensity Modulated ◽

Mediastinal Lymphoma ◽

Tissue Sparing

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Does deep inspiration breath hold reduce plan complexity? Multicentric experience of left breast cancer radiotherapy with volumetric modulated arc therapy

Physica Medica ◽

10.1016/j.ejmp.2019.02.018 ◽

2019 ◽

Vol 59 ◽

pp. 79-85 ◽

Cited By ~ 5

Author(s):

Serenella Russo ◽

Marco Esposito ◽

Victor Hernandez ◽

Jordi Saez ◽

Francesca Rossi ◽

...

Keyword(s):

Breast Cancer ◽

Volumetric Modulated Arc Therapy ◽

Left Breast ◽

Breath Hold ◽

Deep Inspiration ◽

Cancer Radiotherapy ◽

Deep Inspiration Breath Hold ◽

Breast Cancer Radiotherapy ◽

Arc Therapy

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Left Anterior Descending Coronary Artery Dose-Sparing Effects of Volumetric Modulated Arc Therapy in Patients Ineligible for Deep-Inspiration Breath-Hold in Left Breast Radiation Therapy

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2018.07.1684 ◽

2018 ◽

Vol 102 (3) ◽

pp. e615

Author(s):

B. Tomasik ◽

A.G. Papis Ubych ◽

J.P. Chalubinska-Fendler ◽

J. Fijuth

Keyword(s):

Radiation Therapy ◽

Coronary Artery ◽

Volumetric Modulated Arc Therapy ◽

Left Breast ◽

Breath Hold ◽

Deep Inspiration ◽

Deep Inspiration Breath Hold ◽

Arc Therapy ◽

Dose Sparing

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Deep Inspiration Breath-Hold (DIBH) for Locoregional Breast Irradiation using Volumetric Modulated Arc Therapy (VMAT) and Intensity Modulated Proton Therapy (IMPT): A Dosimetric Comparison to Cardiac Substructure

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2020.07.1080 ◽

2020 ◽

Vol 108 (3) ◽

pp. e43

Author(s):

P. Loap ◽

F. Goudjil ◽

B. Baron ◽

M. Ribeiro ◽

A. Fourquet ◽

...

Keyword(s):

Proton Therapy ◽

Volumetric Modulated Arc Therapy ◽

Breath Hold ◽

Deep Inspiration ◽

Breast Irradiation ◽

Deep Inspiration Breath Hold ◽

Dosimetric Comparison ◽

Intensity Modulated Proton Therapy ◽

Intensity Modulated ◽

Arc Therapy

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Is 5 mm breath-hold window (BHW) sufficient to treat carcinoma left breast patients post-conservative surgery: a comparative study using forward intensity-modulated radiotherapy (FIMRT) and volumetric modulated arc therapy (VMAT)

Journal of Radiotherapy in Practice ◽

10.1017/s1460396920000837 ◽

2020 ◽

pp. 1-9

Author(s):

Karthikeyan Kalyanasundaram ◽

Subramani Vellaiyan

Keyword(s):

Breathing Pattern ◽

Volumetric Modulated Arc Therapy ◽

Intensity Modulated Radiotherapy ◽

Conservative Surgery ◽

Target Volume ◽

Left Breast ◽

Breath Hold ◽

Deep Inspiration ◽

Intensity Modulated ◽

Arc Therapy

Abstract Purpose: The purpose of the study was to evaluate the impact of changes in breathing pattern inside the breath-hold window (BHW) during deep inspiration breath hold treatment for carcinoma left breast patients post-conservative surgery. Methods: Ten patients of carcinoma left breast post-conservative surgery were prospectively selected. Three sets of CT plain images were acquired, one with 5 mm deep inspiration BHW (DIBHR) and the other one with 1 mm BHW matching the lower threshold (DIBHL) and the third one with 1 mm BHW matching the upper threshold (DIBHH) as DIBHR. For all patients, forward intensity-modulated radiotherapy (FIMRT) and volumetric modulated arc therapy (VMAT) plans were generated in the 5 mm BHW CT series and the same plan being copy and pasted in other series. Target volume doses and critical structure doses were tabulated. Results: Planning target volume coverage was adequate and no significant differences were found in any CT series. Significant differences noted in average left lung V5%, V10% and V18% doses between DIBHR versus DIBHH (p values = 0·0461, 0·0283 and 0·0213, respectively) and DIBHL versus DIBHH (p values = 0·0434, 0·0484 and 0·0334, respectively) for FIMRT plans and V18% doses in DIBHR versus DIBHH (p = 0·0067) in VMAT. No differences in heart and apex of heart doses were found. Left anterior descending artery (LAD) mean doses were significant in DIBHL versus DIBHR, DIBHR versus DIBHH and DIBHL versus DIBHH (p = 0·0012, 0·0444 and 0·0048, respectively) series for FIMRT plans and DIBHR versus DIBHH and DIBHL versus DIBHH (p = 0·0341, 0·0001) for VMAT plans. Finding: The changes in the breathing pattern inside DIBH window level cause some variation in LAD doses and no other significant differences in any parameters noted, so care should be taken while treating patients with preexisting cardiac conditions.

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