Analysis of Contrast-Enhanced Intravascular Ultrasound Images for the Assessment of Coronary Plaque Neoangiogenesis: Another Step Closer to the Identification of the Vulnerable Plaque

2012 ◽  
Vol 18 (15) ◽  
pp. 2207-2213 ◽  
Author(s):  
E. Ruiz ◽  
Theodore Papaioannou ◽  
Manolis Vavuranakis ◽  
Christodoulos Stefanadis ◽  
Morteza Naghavi ◽  
...  
2010 ◽  
Vol 36 (8) ◽  
pp. 1245-1258 ◽  
Author(s):  
Arash Taki ◽  
Holger Hetterich ◽  
Alireza Roodaki ◽  
S.K. Setarehdan ◽  
Gozde Unal ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-7
Author(s):  
Ju Hwan Lee ◽  
Yoo Na Hwang ◽  
Ga Young Kim ◽  
Eun Seok Shin ◽  
Sung Min Kim

The purpose of this study was to characterize cardiovascular tissue components and analyze the different tissue properties for predicting coronary vulnerable plaque from intravascular ultrasound (IVUS) images. For this purpose, sequential IVUS image frames were obtained from human coronary arteries using 20 MHz catheters. The plaque regions between the intima and media-adventitial borders were manually segmented in all IVUS images. Tissue components of the plaque regions were classified into having fibrous tissue (FT), fibrofatty tissue (FFT), necrotic core (NC), or dense calcium (DC). The media area and lumen diameter were also estimated simultaneously. In addition, the external elastic membrane (EEM) was computed to predict the vulnerable plaque after the tissue characterization. The reliability of manual segmentation was validated in terms of inter- and intraobserver agreements. The quantitative results found that the FT and the media as well as the NC would be good indicators for predicting vulnerable plaques in IVUS images. In addition, the lumen was not suitable for early diagnosis of vulnerable plaque because of the low significance compared to the other vessel parameters. To predict vulnerable plaque rupture, future study should have additional experiments using various tissue components, such as the EEM, FT, NC, and media.


1997 ◽  
Vol 3 (S2) ◽  
pp. 265-266
Author(s):  
K. J. Dixon ◽  
D. G. Vince ◽  
R. M. Cothren ◽  
J. F. Cornhill

Atherosclerosis is a degenerative arterial disease that leads to the gradual blockage of vessels due to plaque formation or acute ischaemic events such as plaque rupture. A thorough understanding of plaque morphology is necessary in the determination of factors underlying coronary artery disease. Intravascular ultrasound (IVUS) represents a diagnostic technique that provides tomographic visualization of coronary arteries. Ultrasound reflects sound at the interfaces between media of different acoustic refractive indices theoretically implying that various components within an ultrasound image should be distinguishable. The aim of this study is to classify plaque lesions using advanced digital image processing into the following categories: adventitia, media, fibrous, necrotic core, and calcified. Examination of plaque composition can yield valuable information necessary in determining the appropriate preventative and mechanical interventions.Diseased samples were obtained from excised human coronary arteries at autopsy. Intravascular ultrasound images were acquired using an HP SONOS clinical IVUS imaging system and 3.5 French 30 MHz catheters.


2018 ◽  
Vol 57 (4) ◽  
pp. 863-876 ◽  
Author(s):  
Tae Joon Jun ◽  
Soo-Jin Kang ◽  
June-Goo Lee ◽  
Jihoon Kweon ◽  
Wonjun Na ◽  
...  

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