Secondary Stroke Prevention in Patients with Cryptogenic Stroke and Patent Foramen Ovale

2008 ◽  
Vol 3 (1) ◽  
pp. 129-141
Author(s):  
Robert Belvis ◽  
Joan Marti-Fabregas ◽  
Dolores Cocho ◽  
Josep L. Marti-Vilalta
2018 ◽  
Vol 3 (2) ◽  
pp. 84-91 ◽  
Author(s):  
Kristy Yuan ◽  
Scott Eric Kasner

The patent foramen ovale (PFO), given its high prevalence in the general population and especially in patients with cryptogenic stroke, has long generated investigation and debate on its propensity for stroke by paradoxical embolism and its management for stroke prevention. The pendulum has swung for percutaneous PFO closure for secondary stroke prevention in cryptogenic stroke. Based on a review of current evidence, the benefit from PFO closure relies on careful patient selection: those under the age of 60 years with few to no vascular risk factors and embolic-appearing stroke deemed cryptogenic after thorough evaluation. As these data look towards influencing guideline statements and device approvals in the future, patient selection remains the crucial ingredient for clinical decision making and future trials.


2006 ◽  
Vol 3 (2) ◽  
pp. 129-141 ◽  
Author(s):  
Robert Belvis ◽  
Joan Marti-Fabregas ◽  
Dolores Cocho ◽  
Josep L. Marti-Vilalta

Stroke ◽  
2018 ◽  
Vol 49 (6) ◽  
pp. 1443-1450 ◽  
Author(s):  
Michelle H. Leppert ◽  
Sharon N. Poisson ◽  
John D. Carroll ◽  
David E. Thaler ◽  
Chong H. Kim ◽  
...  

2009 ◽  
Vol 53 (21) ◽  
pp. 2014-2018 ◽  
Author(s):  
Patrick T. O'Gara ◽  
Steven R. Messe ◽  
E. Murat Tuzcu ◽  
Gloria Catha ◽  
John C. Ring

Author(s):  
Ji Y. Chong ◽  
Michael P. Lerario

The presence of a patent foramen ovale (PFO) is associated with cryptogenic stroke, especially in young patients. Medical therapy for patients with stroke and PFO includes antiplatelet therapy or anticoagulation. PFO closure is not routinely recommended for stroke prevention.


Circulation ◽  
2009 ◽  
Vol 119 (20) ◽  
pp. 2743-2747 ◽  
Author(s):  
Patrick T. O'Gara ◽  
Steven R. Messe ◽  
E. Murat Tuzcu ◽  
Gloria Catha ◽  
John C. Ring

Stroke ◽  
2012 ◽  
Vol 43 (2) ◽  
pp. 422-431 ◽  
Author(s):  
Georgios D. Kitsios ◽  
Issa J. Dahabreh ◽  
Abd Moain Abu Dabrh ◽  
David E. Thaler ◽  
David M. Kent

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