Molecular Modeling Applied to Design of Cysteine Protease Inhibitors – A Powerful Tool for the Identification of Hit Compounds Against Neglected Tropical Diseases

2020 ◽  
pp. 63-110
Author(s):  
Igor José dos Santos Nascimento ◽  
Thiago Mendonça de Aquino ◽  
Paulo Fernando da Silva Santos-Júnior ◽  
João Xavier de Araújo-Júnior ◽  
Edeildo Ferreira da Silva-Júnior
Keyword(s):  
Molecular Modeling ◽  
Protease Inhibitors ◽  
Cysteine Protease ◽  
Neglected Tropical Diseases ◽  
Tropical Diseases ◽  
Cysteine Protease Inhibitors

Evaluation of a microassay for human kininogens as cysteine protease inhibitors

1991 ◽  
Vol 26 (2) ◽  
pp. 113-124 ◽  
Author(s):  
Tove S. Karlsrud ◽  
Ansgar O. Aasen ◽  
Harald T. Johansen
Keyword(s):  
Protease Inhibitors ◽  
Cysteine Protease ◽  
Cysteine Protease Inhibitors

The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors

2007 ◽  
Vol 15 (15) ◽  
pp. 5340-5350 ◽  
Author(s):  
Cláudia Valente ◽  
Rui Moreira ◽  
Rita C. Guedes ◽  
Jim Iley ◽  
Mohammed Jaffar ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Cysteine Protease ◽  
Cysteine Protease Inhibitors

scholarly journals Design, Synthesis, Evaluation and Thermodynamics of 1-Substituted Pyridylimidazo[1,5-a]Pyridine Derivatives as Cysteine Protease Inhibitors

PLoS ONE ◽  
2013 ◽  
Vol 8 (8) ◽  
pp. e69982 ◽  
Author(s):  
Mohd Sajid Khan ◽  
Mohd Hassan Baig ◽  
Saheem Ahmad ◽  
Shapi Ahmad Siddiqui ◽  
Ashwini Kumar Srivastava ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Cysteine Protease ◽  
Pyridine Derivatives ◽  
Cysteine Protease Inhibitors ◽  
Design Synthesis

ChemInform Abstract: Synthesis of Macrocyclic Trypanosomal Cysteine Protease Inhibitors.

ChemInform ◽  
2009 ◽  
Vol 40 (14) ◽  
Author(s):  
Yen Ting Chen ◽  
Ricardo Lira ◽  
Elizabeth Hansell ◽  
James H. McKerrow ◽  
William R. Roush
Keyword(s):  
Protease Inhibitors ◽  
Cysteine Protease ◽  
Cysteine Protease Inhibitors

A comparative study of warheads for design of cysteine protease inhibitors

2017 ◽  
Vol 27 (22) ◽  
pp. 5031-5035 ◽  
Author(s):  
Daniel G. Silva ◽  
Jean F.R. Ribeiro ◽  
Daniela De Vita ◽  
Lorenzo Cianni ◽  
Caio Haddad Franco ◽  
...  
Keyword(s):  
Comparative Study ◽  
Protease Inhibitors ◽  
Cysteine Protease ◽  
Cysteine Protease Inhibitors
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