Primary Cutaneous Lymphomas; A review of a rare but diverse cutaneous tumour

2018 ◽  
Vol 3 (2) ◽  
pp. 1
Author(s):  
Imasogie D E ◽  
Azeke E A
Keyword(s):  
Teaching Hospital ◽  
Case Reports ◽  
Laboratory Unit ◽  
Benin City ◽  
Cutaneous Lymphomas ◽  
Rare Tumours ◽  
Index Study ◽  
Large Populations ◽  
Skin Biopsies ◽  
The University

Title: Primary Cutaneous Lymphomas; University of Benin Teaching Hospital Experience Introduction: Primary cutaneous lymphomas (CLs) are a heterogeneous group of extra nodal non-Hodgkin lymphomas (NHL) which are confined to the skin at diagnosis. The skin is the second most common site of extra nodal lymphoma. They are rare tumours accounting for 18% of cases of extra nodal NHL. The goal of this study is to determine the prevalence of primary cutaneous lymphomas at the University of Benin, Teaching Hospital, Benin City, Edo State, Nigeria, vis-a-vis reviewing the existing literature on the subject matter. Methodology: A 10-year retrospective study of primary CLs seen in UBTH from January 2004- December 2013. Skin biopsies were received fixed in 10% formalin in the laboratory unit of the Department of Morbid Anatomy, UBTH, processed in paraffin wax, sectioned and stained with Haematoxylin and Eosin. Histology slides were retrieved, studied and lesions characterized. Result: There were 375 cases of histologically diagnosed cutaneous tumours. The ages of the patients in this study ranged from 1 to 111 years. Their mean age was 38.32 years (SD = 19.38. There were 192 females (51.2%) and 183 males (48.8%) giving a female to male ratio of 1.05:1. Keratinocytic tumours were the most common lesions seen. There was no case of primary cutaneous lymphoma seen in this study giving a prevalence of 0%. Discussion: Primary CLs are rare tumours. Previous studies in Nigeria and Ghana like the index study did not report a case of CLs. This is unlike the report from Lagos, Nigeria where CLs have been reported. So by extension, although CLs are rare we should not foreclose the possibility of finding isolated cases in our environment. Conclusion: We align with the submission of Bradford et al that further investigations using large populations and molecular tools are warranted to elucidate the aetiology of the diverse spectrum of CLs. Despite this, we trust without prejudice that case reports and institutional base studies as invaluable means in the gathering of data, especially for rare tumours like CLs.

scholarly journals A 5-year Retrospective Study on Alopecia in a Tertiary Hospital in Southern Nigeria

2020 ◽  
Vol 8 (3) ◽  
pp. 175-182
Author(s):  
C.R. Madubuko ◽  
B.U. Okwara
Keyword(s):  
Retrospective Study ◽  
Teaching Hospital ◽  
Hair Loss ◽  
Lupus Erythematosus ◽  
Tertiary Hospital ◽  
Discoid Lupus Erythematosus ◽  
Female Ratio ◽  
Benin City ◽  
The University ◽  
Étude Rétrospective

Background: Alopecia is a common condition accounting for the top ten morbidities seen in patients that present at dermatology outpatient clinics in Nigeria.Aim: This retrospective study aimed at documenting the prevalence and types of alopecia in the skin clinic at the University of Benin Teaching Hospital between December 2014 and December 2019. Methods: The medical records of all patients with alopecia attending dermatological outpatient clinic between December 2014 to December 2019 were analyzed retrospectively for this descriptive observational study. An approval for the study was obtained from the Ethics Committee of the University of Benin Teaching Hospital, Benin-city, Nigeria. The diagnosis of Hair loss was essentially clinical, confirmed where expedient with a skin biopsy. Dermatological tools like Dermoscopes were also used to boost diagnostic accuracy when necessary. The patients were also evaluated for presence of other cutaneous and systemic disorders. Results: During the 5year study period, 106 patients with hair loss (6.6%%) were observed. The youngest patient was 2months old and the oldest patient was 90years old. The males constituted 61.3% of patients observed while the females accounted for 38.7% of patients seen. The male to female ratio was 1.6:1. Discoid lupus erythematosus of the scalp, was the most common disorder 29(29.4%). Alopecia areata occurred in23(27.7%); tinea capitis in 15(14,2%); Acne keloidalis nuchae in 14(13.2%); seborrheic dermatitis10(9.4%); and folliculiltis delcavans 9(8.5%). Less commonly observed causes of alopecia included androgenetic alopecia 2(1.9%); traction alopecia 2(1.9%); lichenplanopilaris 1(0.9%) and nevus sebaceum 1(0.9%). Conclusion: There is a need for studies to further describe and proffer solutions to common causes of alopecia in our community. Keywords: Retrospective study, Alopecia, Tertiary hospital, Benin French title: Une étude rétrospective de cinq (5) ans sur l'alopécie dans un hôpital tertiaire du Sud au Nigéria Contexte général de l'étude: L'alopécie est une condition de classement courante qui explique les dix principales morbidités observées chez les patients qui se présentent dans des cliniques externes de dermatologie au Nigéria.Objectif de l'étude: Cette étude rétrospective visait à documenter la prévalence et les types d'alopécie à la clinique externe de dermatologie de l'hôpital universitaire du Bénin entre décembre 2014 et décembre 2019.Méthode de l'étude: Il s'agissait d'une étude rétrospective de patients présentant principalement une perte de cheveux. Les données ont été obtenues à partir des dossiers cliniques et des notes cliniques des patients.Résultats de l'étude: Au cours de la période d'étude de 5 ans, 106 patients sur 1 600 personnes fréquentant la clinique de la peau ont eu une perte de cheveux constituant une prévalence de 6,6%. Les patients vus étaient âgés de 2 mois à 90 ans. Plus d'hommes (61,3%) que de femmes (38,7%) ont été vus; avec un rapport de 1,6: 1. Le lupus érythémateux discoïde du cuir chevelu était le trouble le plus courant «insérer un nombre absolu» (29,4%). L'alopécie areata est survenue en «insérer le nombre absolu» 27,7%; tineacapitis en «insérer le nombre absolu» 14,2%; Acné  keloidalisnuchae en «insérer le nombre absolu» 13,2%; dermatite séborrhéique «insérer le nombre absolu» 9,4%; et folliculiltisdelcavans «insérer le nombre absolu» 8,5%. Les causes d'alopécie moins fréquemment observées comprenaient l'androgénétopécie (1,9%); alopécie de traction (1,9%); lichenplanopilaris (0,9%) et naevus sébacé (0,9%)Conclusion: Des études sont nécessaires pour décrire et proposer des solutions aux causes courantes d'alopécie dans notre communauté. Mots-clés: Alopécie, lupus érythémateux discoïde, alopéciaareata, acné keloidalisnuchae

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