Significance of Incidentally Detected Subcentimeter Enhancing Lesions on Preoperative Breast MRI: Role of Second-Look Ultrasound in Lesion Detection and Management

2015 ◽  
Vol 204 (3) ◽  
pp. W357-W362 ◽  
Author(s):  
Se Jin Nam ◽  
Eun-Kyung Kim ◽  
Min Jung Kim ◽  
Hee Jung Moon ◽  
Jung Hyun Yoon
2011 ◽  
Vol 116 (6) ◽  
pp. 886-904 ◽  
Author(s):  
M. L. Luciani ◽  
F. Pediconi ◽  
M. Telesca ◽  
F. Vasselli ◽  
V. Casali ◽  
...  

2019 ◽  
Vol 4 (3) ◽  
pp. 368
Author(s):  
AhmedM. A. Ahmed ◽  
TarekA. M. Ahmed ◽  
MahmoudR Shehata ◽  
Marwa Makboul ◽  
MoahamedA. M. Ibrahem

2015 ◽  
Vol 25 (10) ◽  
pp. 2830-2839 ◽  
Author(s):  
Paola Clauser ◽  
Luca A. Carbonaro ◽  
Martina Pancot ◽  
Rossano Girometti ◽  
Massimo Bazzocchi ◽  
...  

2014 ◽  
Vol 20 (3) ◽  
pp. 243-248 ◽  
Author(s):  
Jacopo Nori ◽  
Icro Meattini ◽  
Elisabetta Giannotti ◽  
Dalmar Abdulcadir ◽  
Giovanna Mariscotti ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1575
Author(s):  
Lucia Zanoni ◽  
Riccardo Mei ◽  
Lorenzo Bianchi ◽  
Francesca Giunchi ◽  
Lorenzo Maltoni ◽  
...  

The primary aim of the study was to evaluate the role of [18F]Fluciclovine PET/CT in the characterization of intra-prostatic lesions in high-risk primary PCa patients eligible for radical prostatectomy, in comparison with conventional [11C]Choline PET/CT and validated by prostatectomy pathologic examination. Secondary aims were to determine the performance of PET semi-quantitative parameters (SUVmax; target-to-background ratios [TBRs], using abdominal aorta, bone marrow and liver as backgrounds) for malignant lesion detection (and best cut-off values) and to search predictive factors of malignancy. A six sextants prostate template was created and used by PET readers and pathologists for data comparison and validation. PET visual and semi-quantitative analyses were performed: for instance, patient-based, blinded to histopathology; subsequently lesion-based, un-blinded, according to the pathology reference template. Among 19 patients included (mean age 63 years, 89% high and 11% very-high-risk, mean PSA 9.15 ng/mL), 45 malignant and 31 benign lesions were found and 19 healthy areas were selected (n = 95). For both tracers, the location of the “blinded” prostate SUVmax matched with the lobe of the lesion with the highest pGS in 17/19 cases (89%). There was direct correlation between [18F]Fluciclovine uptake values and pISUP. Overall, lesion-based (n = 95), the performance of PET semiquantitative parameters, with either [18F]Fluciclovine or [11C]Choline, in detecting either malignant/ISUP2-5/ISUP4-5 PCa lesions, was moderate and similar (AUCs ≥ 0.70) but still inadequate (AUCs ≤ 0.81) as a standalone staging procedure. A [18F]Fluciclovine TBR-L3 ≥ 1.5 would depict a clinical significant lesion with a sensitivity and specificity of 85% and 68% respectively; whereas a SUVmax cut-off value of 4 would be able to identify a ISUP 4-5 lesion in all cases (sensitivity 100%), although with low specificity (52%). TBRs (especially with threshold significantly higher than aorta and slightly higher than bone marrow), may be complementary to implement malignancy targeting.


2013 ◽  
Vol 11 (1) ◽  
Author(s):  
Brigid K. Killelea ◽  
Baiba J. Grube ◽  
Muhammad Rishi ◽  
Liane Philpotts ◽  
Eliza-Jasmine Tran ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
F. Steinbruecker ◽  
A. Meyer-Baese ◽  
T. Schlossbauer ◽  
D. Cremers

Motion-induced artifacts represent a major problem in detection and diagnosis of breast cancer in dynamic contrast-enhanced magnetic resonance imaging. The goal of this paper is to evaluate the performance of a new nonrigid motion correction algorithm based on the optical flow method. For each of the small lesions, we extracted morphological and dynamical features describing both global and local shape, and kinetics behavior. In this paper, we compare the performance of each extracted feature set under consideration of several 2D or 3D motion compensation parameters for the differential diagnosis of enhancing lesions in breast MRI. Based on several simulation results, we determined the optimal motion compensation parameters. Our results have shown that motion compensation can improve the classification results. The results suggest that the computerized analysis system based on the non-rigid motion compensation technique and spatiotemporal features has the potential to increase the diagnostic accuracy of MRI mammography for small lesions and can be used as a basis for computer-aided diagnosis of breast cancer with MR mammography.


2015 ◽  
Vol 26 (1) ◽  
pp. 19-25
Author(s):  
Alan B. Hollingsworth ◽  
Rebecca G. Stough

Sign in / Sign up

Export Citation Format

Share Document