Sonographic demonstration of a normal thyroid gland excludes ectopic thyroid in patients with thyroglossal duct cyst.

Ectopic thyroid tissue can deposit anywhere in the body. There are several cases reporting papillary thyroid carcinoma (PTC) arising from ectopic tissues; however, these cases largely presented with primary PTC within the native thyroid gland as well. Alternatively, some cases report of PTC found solely in an ectopic thyroglossal duct cyst, but reports of isolated malignancy in other types of ectopic thyroid tissue with normal native tissue are sparse throughout the literature. Here, we present an unusual case of PTC in the midline anterior neck that does not appear to be consistent with a thyroglossal duct cyst, accompanied by a completely benign native thyroid gland, of which only few cases have been reported.

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Ectopic thyroid gland simulating a thyroglossal duct cyst: A case report

Journal of Pediatric Surgery ◽

10.1016/s0022-3468(96)90355-3 ◽

1996 ◽

Vol 31 (1) ◽

pp. 208

Author(s):

Sigmund Ein

Keyword(s):

Case Report ◽

Thyroid Gland ◽

Thyroglossal Duct Cyst ◽

Ectopic Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct

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Papillary Carcinoma Arising from Ectopic Thyroid Gland in the Wall of a Thyroglossal Duct Cyst

Pathology - Research and Practice ◽

10.1016/s0344-0338(11)80850-2 ◽

1993 ◽

Vol 189 (10) ◽

pp. 1228-1229 ◽

Cited By ~ 6

Author(s):

H. Grabowska

Keyword(s):

Thyroid Gland ◽

Papillary Carcinoma ◽

Thyroglossal Duct Cyst ◽

Ectopic Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct

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Thyroglossal Duct Cyst Papillary Carcinoma With Airway Compromise

Ear Nose & Throat Journal ◽

10.1177/01455613211022077 ◽

2021 ◽

pp. 014556132110220

Author(s):

Po-Kai Huang ◽

Li-Chun Hsieh ◽

Yi-Shing Leu

Keyword(s):

Symptom Relief ◽

Thyroid Tissue ◽

Neck Mass ◽

Thyroglossal Duct Cyst ◽

Ectopic Thyroid ◽

Airway Compromise ◽

Duct Cyst ◽

Complete Excision ◽

Thyroglossal Duct ◽

Ectopic Thyroid Tissue

Thyroglossal duct cysts are typically benign and usually asymptomatic. Malignant transformation is uncommon. Intralaryngeal extension is rare and results in dysphonia or dyspnea. There is no literature nowadays reporting the thyroglossal duct cyst carcinoma combining the clinical features of intralaryngeal extension. The authors present a case of progressive hoarseness and midline neck mass for 2 years. The laryngoscope and computed tomography revealed a 6-cm thyroglossal duct cyst containing ectopic thyroid tissue with intralaryngeal extension and causing airway obstruction. Complete excision with Sistrunk operation revealed papillary thyroid carcinoma. The patient resumed normal phonation after the surgery. There was no evidence of tumor recurrence and no hoarseness or dyspnea at 6 months follow up. This is the first reported case of a huge thyroglossal duct cyst carcinoma with intralaryngeal extension causing airway compromise. Complete excision of tumor is essential and vital to the symptom relief. A thyroglossal duct cyst carcinoma with endolaryngeal involvement should be considered in the differential diagnosis when the case has a massive midline neck mass with ectopic thyroid tissue and develops dyspnea or hoarseness concurrently.

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