BRAFV600E mutation: a potential predictor of more than a Sistrunk’s procedure in patients with thyroglossal duct cyst carcinoma and a normal thyroid gland

AbstractObjective:We report an extremely rare case of the simultaneous occurrence of a thyroglossal duct cyst and a lingual thyroid in the absence of an orthotopic thyroid gland, in a seven-year-old girl from South India.Method:Case report and a review of the English language literature on the subject.Results:The patient presented with a mass on the tongue that had been present for three years, and an anterior neck swelling that had been present for two years. Examination revealed a midline, pinkish, firm mass present on the posterior one-third of the tongue. The neck showed a midline cystic swelling in the infrahyoid position. Radiological imaging confirmed the clinical findings, revealing the absence of her thyroid gland in the normal location. Sistrunk's procedure was performed leaving behind a lingual thyroid. At 13-month follow up, the patient was euthyroid with no recurrence.Conclusion:To our knowledge the association of a lingual thyroid and a thyroglossal cyst has only been reported once in the literature. The presence of a lingual thyroid in the absence of a normally located thyroid gland or functioning thyroid tissue along the thyroglossal tract, confirmed by radionuclide and computed tomography imaging, may indicate the failure of the normal descent of the thyroid gland during embryonic development. This probable absence of the descent of the thyroid raises questions regarding the origin of thyroglossal duct cysts.

Download Full-text

Scintigraphic Demonstration of Ectopic Thyroid Tissue in a Thyroglossal Duct Cyst in the Presence of a Normal Thyroid

Clinical Nuclear Medicine ◽

10.1097/rlu.0b013e31822920f5 ◽

2011 ◽

Vol 36 (12) ◽

pp. 1142-1143 ◽

Cited By ~ 1

Author(s):

Sampath Santhosh ◽

Bhagwant Rai Mittal ◽

Koramadai Karuppusamy Kamaleshwaran ◽

Rahul Parghane ◽

Anish Bhattacharya ◽

...

Keyword(s):

Thyroid Tissue ◽

Thyroglossal Duct Cyst ◽

Ectopic Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct ◽

Normal Thyroid ◽

Ectopic Thyroid Tissue

Download Full-text

Synchronous Papillary Carcinoma in Thyroglossal Duct Cyst and Thyroid Gland Associated to Untreated Midline Cervical Cleft: A Case Report

JOURNAL OF CASE REPORTS AND STUDIES ◽

10.15744/2348-9820.7.108 ◽

2019 ◽

Vol 7 (1) ◽

Author(s):

Choukry K ◽

Khdim M ◽

Beghdad M ◽

Choukry S ◽

Rouadi S ◽

...

Keyword(s):

Case Report ◽

Thyroid Gland ◽

Papillary Carcinoma ◽

Thyroglossal Duct Cyst ◽

Duct Cyst ◽

Thyroglossal Duct ◽

Midline Cervical Cleft

Download Full-text

A Case of Contemporaneous Occurrence of Thyroglossal Duct Cyst and Lingual Thyroid without the Orthotopic Thyroid Gland

Korean Journal of Otorhinolaryngology - Head and Neck Surgery ◽

10.3342/kjorl-hns.2013.56.9.606 ◽

2013 ◽

Vol 56 (9) ◽

pp. 606

Author(s):

Seung Woo Kim ◽

Yun Ey Chung ◽

Yoon Jung Kim ◽

Jeon Ha Choi

Keyword(s):

Thyroid Gland ◽

Thyroglossal Duct Cyst ◽

Lingual Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct

Download Full-text

Thyroglossal duct cyst carcinoma

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v6i2.29137 ◽

2016 ◽

Vol 6 (2) ◽

pp. 172

Author(s):

Ashim Kumar Biswas ◽

Kazi Shameemus Salam ◽

Md. Mosleb Uddin ◽

Kanu Lal Saha ◽

Belayat Hossain Siddiquee ◽

...

Keyword(s):

Thyroid Gland ◽

Papillary Carcinoma ◽

Cystic Lesion ◽

Histopathological Examination ◽

Rare Condition ◽

Thyroglossal Duct Cyst ◽

Thyroglossal Cyst ◽

Duct Cyst ◽

Thyroglossal Duct

Thyroglossal duct cyst carcinoma in a rare condition. Only around 250 cases of malignant thyroglossal cyst have been reported as far. We report a 45 years old women presenting with a painless swelling in the midline in the upper part of front of neck for 1 yr. This swelling moves with deglutition, multilobulated moves up on protrusion of tongue. FNAC revealed cystic lesion compatible with thyroglossal duct cyst. Ultrasonogram revealed mass is separated from thyroid gland. Patient underwent sistnmk's operation and tissue was sent for histopathological examination and report reveled papillary carcinoma of thyroglossal duct cyst.

Download Full-text