Can mean platelet volume and red blood cell distribution width show disease activity in rheumatoid arthritis?

2016 ◽  
Vol 10 (9) ◽  
pp. 967-974 ◽  
Author(s):  
Duygu Tecer ◽  
Melek Sezgin ◽  
Arzu Kanık ◽  
Nurgül Arıncı İncel ◽  
Özlem Bölgen Çimen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Blood Cell ◽  
Disease Activity ◽  
Red Blood Cell ◽  
Mean Platelet Volume ◽  
Cell Distribution ◽  
Platelet Volume ◽  
Distribution Width ◽  
Red Blood Cell Distribution

scholarly journals Analysis of mean platelet volume and red blood cell distribution width in recurrent epistaxis

2018 ◽  
Vol 18 (2) ◽  
pp. 67-70 ◽  
Author(s):  
Ali Ekber Karabulut ◽  
Yunsur Çevik ◽  
Emine Emektar ◽  
Şeref Kerem Çorbacioğlu ◽  
Seda Dağar ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Mean Platelet Volume ◽  
Cell Distribution ◽  
Platelet Volume ◽  
Distribution Width ◽  
Recurrent Epistaxis ◽  
Red Blood Cell Distribution

scholarly journals Red Blood Cell Distribution Width-to-Platelet Ratio Inversely Correlates with Indicators of Disease Activity Status in Rheumatoid Arthritis Patients

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Amela Dervišević ◽  
Amila Muhić ◽  
Asija Začiragić ◽  
Almir Fajkić ◽  
Lejla Dervišević ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Blood Cell ◽  
Disease Activity ◽  
Red Blood Cells ◽  
Red Blood Cell ◽  
Blood Cells ◽  
Cell Distribution ◽  
Distribution Width ◽  
Low Disease Activity ◽  
Red Blood Cell Distribution

AbstractIntroduction: Present study was performed to verify red blood cell distribution width-to-platelet ratio (RPR) level in rheumatoid arthritis (RA) patients and to examine its correlation with clinical and biochemical indicators of disease activity status.Methods: In this cross-sectional analytical study, 67 patients with RA and 34 age- and gender-matched healthy control subjects were enrolled. Based on the disease activity score 28-ESR (DAS28-ESR), RA patients were divided into subgroups: low disease activity (n=20), moderate disease activity (n=22) and high disease activity (n=25). Laboratory tests included erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) concentration, platelet count (PLT), red blood cells count (RBC), red blood cells distribution width (RDW) and fibrinogen concentration. Statistical analyses were carried out using SPSS 13 software. Statistical significance was set at a p-value less than 0.05.Results: There was statistically significant difference (p=0.006) between RPR in RA patients with different stages of disease activity, with higher values in patients with low disease activity. The RPR showed statistically significant negative correlations with ESR (rho= -0.309; p=0.012), CRP (rho= -0.421; p=0.001), swollen joint count - SJC (rho = -0.368; p=0.002) and tender joint count - TJC (rho= -0.355; p=0.003), DAS28-ESR (rho= -0.409; p=0.001), DAS28-CRP (rho= -0.422; p<0.0005) and Visual analogue scale - VAS (rho= -0.260; p=0.033) in RA patients.Conclusion: The present study provided evidence that the lower RPR values in RA patients are significantly associated with the disease activity indicators.

The relationship between complete blood count parameters and Fontaine’s Stages in patients with peripheral arterial disease

Vascular ◽  
2014 ◽  
Vol 22 (6) ◽  
pp. 427-431 ◽  
Author(s):  
Sinan Demirtas ◽  
Oguz Karahan ◽  
Suleyman Yazici ◽  
Orkut Guclu ◽  
Ahmet Caliskan ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Mean Platelet Volume ◽  
Arterial Disease ◽  
Cell Distribution ◽  
Platelet Volume ◽  
Distribution Width ◽  
Peripheral Arterial ◽  
Red Blood Cell Distribution

Objective The aim of the present study is to evaluate whether blood count parameters differ according to the stages of Fontaine’s classification and to investigate the relationship between hemogram parameters and the severity of the disease. Method Eighty-two peripheral arterial disease patients were examined prospectively. Patients were classified according to the Fontaine classification system. Fifty newly diagnosed patients were included in the study. The neutrophil-to-lymphocyte ratio, mean platelet volume, and red blood cell distribution width values were recorded. Results Mean neutrophil-to-lymphocyte ratio values were found to be 3.31 ± 1.1% in Stage I, 3.11 ± 1.3% in Stage II, and 3.48 ± 1.1% in Stage III ( p > 0.05). Mean platelet volume values were found to be 7.8 ± 0.6 fl (Stage I), 8.2 ± 1.0 fl (Stage II), and 9.0 ± 0.9 fl (Stage III) ( p < 0.05). Red blood cell distribution width values were found to be 13.6 ± 1.0% in Stage I, 14.8 ± 1.7% in Stage II, and 15.4 ± 2.3% in Stage III, being significantly different among all three stages ( p < 0.05). Conclusion Both red blood cell distribution width and mean platelet volume are found to be associated with the severity of atherosclerotic disease in patients with peripheral arterial disease. This finding hypothesizes that complete blood counting parameters may serve as a beneficial and cost-effective method for monitoring atherosclerotic peripheral disease.

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