scholarly journals Successful determination of imatinib dosage by therapeutic drug monitoring in a case of chronic myeloid leukemia initiating dialysis for acute renal dysfunction.

2021 ◽  
Author(s):  
Ryosuke Nakahara ◽  
Takahiro Sumimoto ◽  
Ryota Tanaka ◽  
Masao Ogata ◽  
Hiroki Itoh
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Therapeutic Drug Monitoring ◽  
Renal Dysfunction ◽  
Drug Monitoring ◽  
Myeloid Leukemia ◽  
Therapeutic Drug ◽  
First Line ◽  
Acute Renal Dysfunction ◽  
First Line Treatment

Imatinib is used as first-line treatment for chronic myeloid leukemia (CML) even in patients with impaired renal function. We successfully used therapeutic drug monitoring to determine the dose for re-administration of imatinib in a CML patient who initiated dialysis for acute renal dysfunction associated with the initial imatinib therapy.

scholarly journals Role of Therapeutic Drug Monitoring and Challenges in the Management of Infantile Chronic Myeloid Leukemia

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Sneha Tandon ◽  
Raviraj Deshpande ◽  
Gaurav Narula ◽  
Maya Prasad ◽  
Amey Paradkar ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Myeloid Leukemia ◽  
Therapeutic Drug

Therapeutic drug monitoring of imatinib in chronic myeloid leukemia: experience from 1216 patients at a centralized laboratory

2012 ◽  
Vol 27 (6) ◽  
pp. 690-697 ◽  
Author(s):  
Stéphane Bouchet ◽  
Karine Titier ◽  
Nicholas Moore ◽  
Régis Lassalle ◽  
Basmah Ambrosino ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Myeloid Leukemia ◽  
Therapeutic Drug

scholarly journals Benefits of Therapeutic Drug Monitoring of First Line Antituberculosis Drugs

2020 ◽  
Vol 20 (2) ◽  
pp. 45-55
Author(s):  
K Prso ◽  
N Zidekova ◽  
M Dohal ◽  
I Porvaznik ◽  
M Prso ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Drug Monitoring ◽  
Plasma Drug Concentration ◽  
Therapeutic Drug ◽  
Plasma Drug ◽  
Therapeutic Level ◽  
First Line ◽  
Antituberculosis Drugs ◽  
Health Related

AbstractTuberculosis is an airborne infectious disease that remains a huge global health-related issue nowadays. Despite constant approvals of newly developed drugs, the use of first-line antituberculosis medicines seems reasonable in drug-susceptible Mycobacterium tuberculosis strains. Therapeutic drug monitoring presents a useful technique for the determination of plasma drug concentration to adjust appropriate dose regimes. In tuberculosis treatment, therapeutic drug monitoring is aiding clinicians in selecting an optimal therapeutic level, which is essential for the personalisation of therapy. This review is aimed at clarifying the use of therapeutic drug monitoring of the first-line antituberculosis drugs in routine clinical practice.

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