scholarly journals A case of bone lesion in a patient with relapsed chronic lymphocytic leukemia and review of the literature

2021 ◽  
Author(s):  
Francesca Bacchiarri ◽  
Alessandro Gozzetti ◽  
Nicola Mondanelli ◽  
Stefano Lazzi ◽  
Monica Bocchia
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Bone Disease ◽  
Bone Lesion ◽  
Fatal Outcome ◽  
Lymphocytic Leukemia ◽  
Bone Lesions ◽  
Review Of The Literature ◽  
Skeletal Involvement ◽  
Line Of Therapy

Skeletal involvement in CLL is very rare. We present a case of ileum bone lesion during in a patient receiving 5th line of therapy. Despite radiotherapy and salvage therapies, subsequent bone lesions led to a fatal outcome. Further studies on the mechanism by which bone disease develops are currently needed.

scholarly journals Mantle cell lymphoma and chronic lymphocytic leukemia: report of a rare disease association and review of the literature

2010 ◽  
Vol 3 (2-3) ◽  
pp. 91-99 ◽  
Author(s):  
Joana Perdigão ◽  
Helena Alaiz ◽  
Paulo Lúcio ◽  
Paula Gameiro ◽  
Marta Sebastião ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Mantle Cell Lymphoma ◽  
Rare Disease ◽  
Cell Lymphoma ◽  
Disease Association ◽  
Lymphocytic Leukemia ◽  
Review Of The Literature ◽  
Mantle Cell

scholarly journals Fulminant Acanthamoeba castellanii Encephalitis in an Ibrutinib-Treated Patient

2020 ◽  
Vol 7 (2) ◽  
Author(s):  
Jessica W Crothers ◽  
Liangge Hsu ◽  
Francisco M Marty
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Tyrosine Kinase ◽  
Treated Patient ◽  
Fatal Outcome ◽  
Acanthamoeba Castellanii ◽  
Lymphocytic Leukemia ◽  
Immunologic Function ◽  
Bruton Tyrosine Kinase

Abstract We report a case of fulminant Acanthamoeba castellanii encephalitis in a patient with chronic lymphocytic leukemia treated with ibrutinib. The unusually rapid neurologic decline and fatal outcome observed are probably related to alterations in immunologic function associated with inhibition of Bruton tyrosine kinase.

Osteolytic bone lesions as a rare sign of progression of chronic lymphocytic leukemia without evidence of Richter syndrome

2011 ◽  
Vol 53 (5) ◽  
pp. 993-995 ◽  
Author(s):  
Michael Mian ◽  
Silvia Cerú ◽  
Atto Billio ◽  
Carlo Rosanelli ◽  
Sergio Cortelazzo
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Bone Lesions ◽  
Richter Syndrome
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