scholarly journals Management of Lytic Bone Disease in Lymphoplasmacytic Lymphoma: A Case Report and Review of the Literature

2021 ◽  
Author(s):  
Mizba Baksh ◽  
Liuyan Jiang ◽  
Unnati Bhatia ◽  
Victoria Alegria ◽  
Taimur Sher ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Disease ◽  
Bone Lesions ◽  
Lymphoplasmacytic Lymphoma ◽  
Review Of The Literature ◽  
Waldenström Macroglobulinemia ◽  
Waldenstrom Macroglobulinemia ◽  
Lytic Bone Lesions

Waldenström Macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is often differentiated from myeloma based on the presence of lytic bone lesions (LBL). However, WM/LPL can present with LBL and management is poorly understood. We describe a case of an 81-year-old woman with LPL who presented with LBL and was successfully treated with chemoimmunotherapy.

scholarly journals Symptomatic Hypoalbuminemia as an Indication for Treatment of Waldenström Macroglobulinemia: A Case Report and Review of the Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Jeremy T. Larsen ◽  
Frederick D. Leonard
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Primary Reason ◽  
Review Of The Literature ◽  
Gastrointestinal Involvement ◽  
Waldenström Macroglobulinemia ◽  
Symptomatic Disease ◽  
Waldenstrom Macroglobulinemia ◽  
Indication For Treatment

Hypoalbuminemia has been reported as common in patients with symptomatic Waldenström macroglobulinemia (WM), but it is not typically mentioned as a manifestation of the disease in review articles or articles discussing indications for treatment. We present the case of a patient with WM for whom symptomatic hypoalbuminemia was the primary reason for initiating treatment. Except in rare cases of WM with renal or gastrointestinal involvement, hypoalbuminemia is thought to be due to the effects of elevated levels of inflammation-associated cytokines, and it has been associated with greater likelihood of progression of asymptomatic to symptomatic disease, greater disease severity, and poorer prognosis. Hypoalbuminemia in WM may become symptomatic, and it may be a reason to initiate treatment if symptoms affect quality of life.

Lymphangiomatosis: a differential diagnosis of lytic lesions of the temporal bone

2008 ◽  
Vol 122 (11) ◽  
Author(s):  
M B Naguib ◽  
N Al-Jazan ◽  
T Hashem
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Temporal Bone ◽  
Lymphatic System ◽  
Bone Lesions ◽  
Review Of The Literature ◽  
Massive Osteolysis ◽  
Proved Case ◽  
Lytic Lesions ◽  
Lytic Bone Lesions

AbstractObjective:We report a histologically proved case of lymphangiomatosis of the skull, involving the temporal bone and presenting as multiple lytic bone lesions.Method:A case report and a review of the literature concerning lymphangiomatosis are presented.Results:Lymphangiomatosis affecting bones is a rare disorder caused by a congenital malformation of the lymphatic system, resulting in diffuse proliferation of the lymphatic channels and involving bones, parenchymal organs and soft tissue. Involved bones show massive osteolysis and progressive, localised bone resorption.Conclusion:Lymphangiomatosis should be kept in mind in the differential diagnosis of lytic lesions of the skull.

scholarly journals Management of lytic bone disease in lymphoplasmacytic lymphoma: A case report and review of the literature

2021 ◽  
Vol 9 (12) ◽  
Author(s):  
Mizba Baksh ◽  
Liuyan Jiang ◽  
Unnati Bhatia ◽  
Victoria Alegria ◽  
Taimur Sher ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Disease ◽  
Lymphoplasmacytic Lymphoma ◽  
Review Of The Literature

scholarly journals Belated Diagnosis of a Primary Bone Lymphoma of the Elbow: A Rare Case and Review of the Literature

2020 ◽  
pp. 100-107
Author(s):  
Michele Boffano ◽  
Nicola Ratto ◽  
Martina Rezzoagli ◽  
Andrea Conti ◽  
Pietro Pellegrino ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Rare Disease ◽  
Rare Case ◽  
Early Stage ◽  
Bone Lesions ◽  
Review Of The Literature ◽  
Primary Bone Lymphoma ◽  
Lytic Bone Lesions ◽  
Primary Bone ◽  
Bone Lymphoma

Primary non-Hodgkin bone lymphoma (PBL) is a rare disease that accounts for <2% of all lymphomas in adults. PBL can be monostotic or polyostotic, mainly causing destructive and lytic bone lesions frequently located in the femur, humerus, and pelvis. PBL is rarely considered a differential diagnosis of the osteolytic tumor. In addition, PBL is not uncommonly diagnosed with delay because patients do not experience symptoms nor show objective abnormalities in the early stage of disease. Here, we reported a 60-year-old woman with a PBL of the elbow.

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