scholarly journals Myelomatous Ascites and Pleural Effusion in Relapsed Multiple Myeloma

Author(s):  
Mizba Baksh ◽  
Ke Li ◽  
Liuyan Jiang ◽  
Victoria Alegria ◽  
Taimur Sher ◽  
...  

Extramedullary multiple myeloma is seen in advanced and aggressive disease and occurs due to plasma cell infiltration of sites other than the bone marrow. Myelomatous ascites or pleural effusion is seen in less than 1 % of cases and can be differentiated from infectious etiologies based on fluid cytology.

1984 ◽  
Vol 57 (2) ◽  
pp. 351-352 ◽  
Author(s):  
Aimery De Gramon ◽  
Oscar Benitez ◽  
Nicole Smadja ◽  
Philippe Brissaud ◽  
Agnés Sirinelli ◽  
...  

2016 ◽  
Vol 35 (3) ◽  
pp. 323-328 ◽  
Author(s):  
Kosei Matsue ◽  
Yuya Matsue ◽  
Kaoru Kumata ◽  
Yoshiaki Usui ◽  
Yasuhito Suehara ◽  
...  

1984 ◽  
Vol 57 (2) ◽  
pp. 352-353 ◽  
Author(s):  
M. Cavo ◽  
M. Baccarani ◽  
M. Gobbi ◽  
A. Lipizer ◽  
S. Tura

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Michael G. Alexandrakis ◽  
Parascevi Roussou ◽  
Constantina A. Pappa ◽  
Ippokratis Messaritakis ◽  
Athina Xekalou ◽  
...  

In multiple myeloma, there are many factors influencing the growth of the malignant clone in direct and indirect manners. BAFF is a growth factor for myeloma cells. The aim of the study was to measure its circulating levels in 54 pretreatment patients, along with serum levels of other proliferation markers, such as interleukins-6, -10, and -15, CRP, and beta-2 microglobulin, as well as bone marrow plasma cell infiltration and expression of Ki-67 PI, in various stages of the disease and after effective treatment in 28 of them. Serum levels of the previously mentioned factors were measured by ELISA, whereas bone marrow plasma cell infiltration and Ki-67 expression were estimated immunohistochemically. All measured parameters were higher in pretreated myeloma patients compared to healthy population and were also increasing with the progression of the disease. They all also decreased after effective therapy. Furthermore, all pretreatment values correlated to each other. BAFF seems to be an important growth factor for myeloma plasma cells. Measuring its serum levels, along with the previously mentioned cytokines, may provide important information regarding the degree of myeloma cells’ proliferation. Therefore, they all could be used as markers of proliferation and disease activity.


1992 ◽  
Vol 82 (1) ◽  
pp. 46-49 ◽  
Author(s):  
W. E. Terpstra ◽  
H. M. Lokhorst ◽  
F. Blomjous ◽  
O. J. A. Th. Meuwissen ◽  
A. W. Dekker

2011 ◽  
Vol 15 (4) ◽  
pp. 586-590 ◽  
Author(s):  
Shiho Hanawa ◽  
Tetsu Akimoto ◽  
Eisuke Uehara ◽  
Makoto Inoue ◽  
Toshimi Imai ◽  
...  

2002 ◽  
Vol 107 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Münci Yağcı ◽  
Gülsan Türköz Sucak ◽  
Gülen Akyol ◽  
Rauf Haznedar

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