scholarly journals Correlation between ocular pulse amplitude measured by dynamic contour tonometer and colour doppler flow imaging of the arteric retrobulbar vessels

2011 ◽  
Vol 139 (9-10) ◽  
pp. 572-578 ◽  
Author(s):  
Ivan Marjanovic ◽  
Milija Mijajlovic ◽  
Nadezda Covickovic-Sternic ◽  
Djordje Kontic ◽  
Paraskeva Hentova-Sencanic ◽  
...  

Introduction. An altered perfusion of the optic nerve head has been proposed as a pathogenic factor in glaucoma. Objective. The aim of this study was to evaluate the correlation between ocular pulse amplitude (OPA), measured by Dynamic contour tonometer (DCT) and colour Doppler imaging (CDI) of the arteric retro- bulbar vessels. Methods. Twenty patients older than 50 years were examined, and divided into two equal groups. The first group comprised of patients with normal tension glaucoma treated with topical antiglaucomatous therapy, and the second group included patients with ocular hypertension and glaucoma suspicious without any antiglaucomatous therapy. Ocular pulse amplitude (OPA) was measured with DCT. CDI was also performed. We measured haemodynamic parameters of the internal carotid artery (ICA), ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary arteries (PCA). Peak systolic (PSV), end- diastolic (EDV) velocities were measured, and resistance index (RI) and pulsatility index (PI) were calculated. Results Correlation with OPA showed indirect servitude in the RI of the ICA, RI and PI of the CRA, in the first group; and in the PSV and EDV of the ICA, in the RI and PI of the OA, EDV and RI of the CRA, and RI of the PCA, in the second group Conclusion. Increase of OPA was mostly followed by the increase of the parameters (PSV, EDV, RI, and PI) of the arteric retrobulbar vessels in the first group; in the second group, increase of OPA was in almost 50% of parameters followed by their decrease.

2014 ◽  
Vol 231 (04) ◽  
pp. 363-367 ◽  
Author(s):  
J. Katsimpris ◽  
P. Theoulakis ◽  
G. Papadopoulos ◽  
A. Katsimpris ◽  
J. Lepidas ◽  
...  

2019 ◽  
Vol 102 (6) ◽  
pp. 596-600
Author(s):  
Gul Arikan ◽  
Ziya Ayhan ◽  
Mustafa Baris ◽  
Mahmut Kaya ◽  
Taylan Ozturk ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Du Ri Seo ◽  
Seung Joo Ha

Purpose. To compare the ocular pulse amplitude (OPA) lowering effects of preservative-free tafluprost and dorzolamide-timolol fixed combination (DTFC) using dynamic contour tonometry.Methods. In total, 66 eyes of 66 patients with normal tension glaucoma (NTG) (n=34) or primary open angle glaucoma (POAG) (n=32) were included. Patients were divided into two groups: the preservative-free tafluprost-treated group (n=33) and the preservative-free DTFC-treated group (n=33). Intraocular pressure (IOP) was measured using Goldmann applanation tonometry (GAT). OPA was measured using dynamic contour tonometry; corrected OPA (cOPA) was calculated at baseline and at 1 week and 1, 3, and 6 months after treatment.Results. After 6 months of treatment, tafluprost significantly reduced IOP (P<0.001). The OPA lowering effects differed significantly between the two treatment groups (P=0.003). The cOPA-lowering effect of tafluprost (1.09 mmHg) was significantly greater than that of DTFC (0.36 mmHg) after 6 months of treatment (P=0.01).Conclusions. Tafluprost and DTFC glaucoma treatments provided marked OPA and IOP lowering effects. Tafluprost had a greater effect than DTFC; thus, this drug is recommended for patients at risk of glaucoma progression, due to the high OPA caused by large fluctuations in IOP.


2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Mitsushi Fukukita ◽  
Masashi Ido ◽  
Syunsuke Osawa ◽  
Mikio Sasoh ◽  
Motoyasu Furuta ◽  
...  

Purpose. To investigate the effects of nipradilol on retrobulbar hemodynamics.Methods. We investigated normal and normal-tension glaucoma (NTG) eyes. Topical nipradilol (one eye) and placebo eye drops (fellow eye) were instilled for 1 week in volunteers. Nipradilol was also instilled in NTG patients. Ultrasound color Doppler imaging for the posterior vessels was performed before, 2 hr, 1 week (for normal), and at 4 weeks (for NTG).Results. In normal eyes, there were significant decreases in the resistance index (RI) for the temporal short posterior ciliary arteries (PCA) at 2 hr and for the ophthalmic arteries at 1 week. There were no significant changes in the placebo-treated eyes. In the NTG eyes, there was a significant decrease in the RI for the central retinal artery, nasal, and temporal PCA at 2 hr and 4 weeks.Conclusion. Short-term observations found that nipradilol increased the ocular blood flow in normal and NTG eyes.


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