Low filling ratio of the distal nail segment to the medullary canal is a risk factor for loss of anteromedial cortical support: a case control study

Background Anteromedial cortical support apposition (positive and/or neutral cortical relations) is crucial for surgical stability reconstruction in the treatment of trochanteric femur fractures. However, the loss of fracture reduction is frequent in follow-ups after cephalomedullary nail fixation. This paper aimed to investigate the possible predictive risk factors for postoperative loss of anteromedial cortex buttress after nail fixation. Methods A retrospective analysis of 122 patients with AO/OTA 31A1 and A2 trochanteric femur fractures treated with cephalomedullary nails between January 2017 and December 2019 was performed. The patients were classified into two groups according to the postoperative status of the anteromedial cortical apposition in 3D CT images: Group 1 with contact “yes” (positive or anatomic) and Group 2 with contact “No” (negative, loss of contact). The fracture reduction quality score, tip-apex distance (TAD), calcar-referenced TAD (Cal-TAD), Parker ratio, neck-shaft angle (NSA), and the filling ratio of the distal nail segment to medullary canal diameter in anteroposterior (AP) and lateral fluoroscopies (taken immediately after the operation) were examined in univariate and multivariate analyses. Mechanical complications were measured and compared in follow-up radiographs. Results According to the postoperative 3D CT, 84 individuals (69%) were categorized into Group 1, and 38 individuals (31%) were classified as Group 2. The multivariate logistic regression analysis showed that the poor fracture reduction quality score (P < 0.001) and decreasing filling ratio in the lateral view (P < 0.001) were significant risk factors for the loss of anteromedial cortical contact. The threshold value for the distal nail filling ratio in lateral fluoroscopy predicting fracture reduction re-displacement was found to be 53%, with 89.3% sensitivity and 78.9% specificity. The mechanical complication (varus and over lateral sliding) rate was higher in Group 2. Conclusions The fracture reduction quality score and the decreasing filling ratio of the distal nail to the medullary canal in the lateral view (a novel parameter causing pendulum-like movement of the nail) were possible risk factors for postoperative loss of anteromedial cortical support.

An analysis of YouTube videos on oral hygiene practices during coronavirus disease 2019 pandemic

Objectives: The objectives of the study were to examine the usefulness and content of YouTube videos regarding additional oral hygiene practices that need to be taken during the coronavirus disease 2019 (COVID-19) pandemic. Materials and Methods: A search of YouTube videos was performed using the terms “oral health,” “dental hygiene,” “oral health child” and “dental hygiene child” in combination with “COVID-19”. When analyzing each video, the descriptive characteristics such as title, country of origin, date of upload, duration of the video, the number of views, comments, likes, and dislikes were recorded. The quality of the videos were assessed through indices: Video ınformation and quality ındex (VIQI), modified DISCERN, and global quality score (GQS). The content quality score of the videos was examined. Results: The majority of the analyzed videos were uploaded by health-care professionals (67%). About 40% of the videos were slightly useful, and 6% were useful. There was no statistically significant correlation between the source of upload and GQS, VIQI, total content, or modified DISCERN scores (P > 0.05). Highly-watched videos appeared to have a higher total content, VIQI, Modified DISCERN, and GQI scores than poorly-watched videos, but this difference was not statistically significant (P > 0.05). Conclusion: YouTube videos related to oral hygiene practices during COVID-19 pandemic were a limited source for children. Oral health-care professionals and organizations should play an active important role for providing educative oral hygiene-related information on YouTube videos.

Nutrition-Related Mobile Apps in the French App Store: Assessment of Functionality and Quality (Preprint)

BACKGROUND The global burden of disease attributes 20% of deaths to poor nutrition. Although hundreds of nutrition-related mobile applications have been created to help improve this situation and these have been downloaded by millions of users, the effectiveness of integrating these technologies on the adoption of healthy eating remains mixed. Similarly, no significant evaluation of nutrition applications in French, spoken by approximately 300 million people, has yet been identified in the literature. OBJECTIVE The aim of this study is to review which nutrition mobile apps are currently available on the French market, and to carry out an exhaustive assessment of their quality using the Mobile App Rating Scale (MARS) tool. METHODS A screening of apps related to nutritional health was conducted from March 10 to 17, 2021, on the Google Play Store and the French App Store. A shortlist of 15 apps was identified and assessed using the French version of MARS. Eight dietitian nutritionists assigned to assess seven apps. Remaining apps were randomly allocated to ensure four ratings per app. Intraclass correlation was used to evaluate inter-rater agreement. Mean ± SD scores and their distributions for each section and item were calculated. RESULTS The top scores for quality were obtained by Yazio (mean 3.84 ± standard deviation 0.32), FeelEat (3.71 ± 0.47) and BonneApp (3.65 ± 0.09). The engagement scores (Section A) ranged from 1.95 ± 0.5 for iEatBetter to 3.85 ± 0.44 for Feeleat. The functionality scores (Section B) ranged from 2.25 ± 0.54 for Naor to 4.25 ± 0.46 for Yazio. The Aesthetics scores (Section C) ranged from 2.17 ± 0.34 for Naor to 3.88 ± 0.47 for Yazio. The information scores (Section D) ranged from 2.38 ± 0.60 for iEatBetter:Journal alimentaire to 3.73 ± 0.29 for Yazio. The MARS subjective quality (Section E) varied from 1.13 ± 0.26 for Naor and 1.13 ± 0.25 iEatBetter:Journal alimentaire to 2.28 ± 0.88 for Compteur de calories Fatsecret. The specificity of apps varied from 1.38 ± 0.64 for iEatBetter:Journal alimentaire to 3.50 ± 0.91 for Feeleat. The app-specific score was always lower than the subjective quality score that was always lower than the quality score and that was lower than the rating score from the iOS or Android app stores. CONCLUSIONS Although the prevention and information messages regarding nutritional habits are not scientifically verified before marketing, dieteticians-nutritionists evaluated that the apps quality was quite relevant. The subjective quality and mobile app specificities were associated with lower ratings. Further investigations are needed to assess their alignment with recommendations and their long-term impact on users.

Mutu Pelayanan Radiologi Di Balai Besar Kesehatan Paru Masyarakat (BBKPM) Makassar

Services in the field of radiology which are health support services also need to maintain and improve the quality of their services. Radiology is one of the supporting units of health services in establishing the diagnosis of a disease and also needs to maintain and improve the quality of services appropriately and safely, both for patients (users), radiographers (officers) and the community or the surrounding environment. This study aims to determine the quality of radiology services at the Center for Community Lung Health (BBKPM) Makassar. The method used is descriptive research with a quantitative approach. The population is all patients in the radiology installation of the Center for Community Lung Health (BBKPM) with a sample of 158 people. The results showed that the quality of radiology services in terms of timeliness was categorized as very high, namely 91.86%. The cost of Thorax photo examination services is relatively cheap and affordable and the service waiting time reaches a fairly high-quality value of 86.79%. The information aspect reached a high-quality value, namely 85.97%. The technical executor of the Thorax photo examination is carried out by a radiographer and the executor of the diagnostic results is a radiologist (radiology specialist) who has achieved a fairly high-quality score of 97.15%. Aspects of Human Relations have reached a fairly high-quality score of 87.00%. Environmental Aspects achieved a quality value of 97.57%. It is recommended that the Makassar BBKPM management provide a complaint box (suggestion box) in the radiology room to evaluate services.

Factors Associated With Dietary Quality During Initial and Later Stages of the COVID-19 Pandemic in Mexico

Background: The COVID-19 pandemic disrupted the global economy and modified lifestyles. The aim of our study was to identify factors associated with dietary quality, and their frequency, in Mexican adults at the initial and later stages of the pandemic.Methods: Two online surveys were conducted between June and July 2020 (n = 3,131) and between November and December 2020 (n = 1,703 including non-participants from 1st round). A diet quality score was estimated using a short instrument to measure the consumption of several healthy/unhealthy food items. Linear regression models were used to identify the association between pandemic related factors and the diet quality score, adjusted by sociodemographic characteristics. The 2nd round was weighted to represent the 1st round.Results: During the 1st and 2nd rounds only ~12% of the sample perceived that their intake of healthy food decreased, relative to before the pandemic; ~20% perceived that their intake of unhealthy foods increased. Diet quality remained similar between the 1st and 2nd round. The following factors were negatively associated with diet quality: Eating food prepared away-from-home; going out to work ≥4 times/week; decreased time for food preparation; decreased interest in eating healthy; eating more due to anxiety, depression, or boredom; food insecurity; and stockpiling junk food. Purchasing food using a mixed modality of both in-store and home delivery was positively associated with diet quality. With the exception of eating more due to anxiety (reported by 47% of participants), all these factors were reported by a minority of participants during the first round (≤15%). During the 2nd round, there was an increase in the frequency of participants who reported eating food prepared away-from-home, going out to work ≥4 times/week, having less time to prepare food, being more interested in eating healthfully, and a decrease in participants eating more due to anxiety, depression or boredom, or stockpiling junk food.Conclusions: Most participants perceived that their dietary intake improved during both initial and later stages of the pandemic. This might be related to factors associated with higher dietary quality, such as not going out to work, eating homemade food, and online grocery shopping.

FCLQC: fast and concurrent lossless quality scores compressor

Background Advances in sequencing technology have drastically reduced sequencing costs. As a result, the amount of sequencing data increases explosively. Since FASTQ files (standard sequencing data formats) are huge, there is a need for efficient compression of FASTQ files, especially quality scores. Several quality scores compression algorithms are recently proposed, mainly focused on lossy compression to boost the compression rate further. However, for clinical applications and archiving purposes, lossy compression cannot replace lossless compression. One of the main challenges for lossless compression is time complexity, where it takes thousands of seconds to compress a 1 GB file. Also, there are desired features for compression algorithms, such as random access. Therefore, there is a need for a fast lossless compressor with a reasonable compression rate and random access functionality. Results This paper proposes a Fast and Concurrent Lossless Quality scores Compressor (FCLQC) that supports random access and achieves a lower running time based on concurrent programming. Experimental results reveal that FCLQC is significantly faster than the baseline compressors on compression and decompression at the expense of compression ratio. Compared to LCQS (baseline quality score compression algorithm), FCLQC shows at least 31x compression speed improvement in all settings, where a performance degradation in compression ratio is up to 13.58% (8.26% on average). Compared to general-purpose compressors (such as 7-zip), FCLQC shows 3x faster compression speed while having better compression ratios, at least 2.08% (4.69% on average). Moreover, the speed of random access decompression also outperforms the others. The concurrency of FCLQC is implemented using Rust; the performance gain increases near-linearly with the number of threads. Conclusion The superiority of compression and decompression speed makes FCLQC a practical lossless quality score compressor candidate for speed-sensitive applications of DNA sequencing data. FCLQC is available at https://github.com/Minhyeok01/FCLQC and is freely available for non-commercial usage.

EvalDNA: a machine learning-based tool for the comprehensive evaluation of mammalian genome assembly quality

Background To select the most complete, continuous, and accurate assembly for an organism of interest, comprehensive quality assessment of assemblies is necessary. We present a novel tool, called Evaluation of De Novo Assemblies (EvalDNA), which uses supervised machine learning for the quality scoring of genome assemblies and does not require an existing reference genome for accuracy assessment. Results EvalDNA calculates a list of quality metrics from an assembled sequence and applies a model created from supervised machine learning methods to integrate various metrics into a comprehensive quality score. A well-tested, accurate model for scoring mammalian genome sequences is provided as part of EvalDNA. This random forest regression model evaluates an assembled sequence based on continuity, completeness, and accuracy, and was able to explain 86% of the variation in reference-based quality scores within the testing data. EvalDNA was applied to human chromosome 14 assemblies from the GAGE study to rank genome assemblers and to compare EvalDNA to two other quality evaluation tools. In addition, EvalDNA was used to evaluate several genome assemblies of the Chinese hamster genome to help establish a better reference genome for the biopharmaceutical manufacturing community. EvalDNA was also used to assess more recent human assemblies from the QUAST-LG study completed in 2018, and its ability to score bacterial genomes was examined through application on bacterial assemblies from the GAGE-B study. Conclusions EvalDNA enables scientists to easily identify the best available genome assembly for their organism of interest without requiring a reference assembly. EvalDNA sets itself apart from other quality assessment tools by producing a quality score that enables direct comparison among assemblies from different species.