A Case of Bullous Pemphigoid Complicated with Necrotizing Cellulitis of the Foot Successfully Treated with Concurrent High-dose Intravenous Immunoglobulin Therapy

2018 ◽  
Vol 80 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Nobuaki CHOSA ◽  
Shinichiro TSUMORI ◽  
Katsumi OGATA ◽  
Hiroshi HACHISUKA
1997 ◽  
Vol 245 (1) ◽  
pp. 26-31 ◽  
Author(s):  
J. L. M. Jongen ◽  
P. A. van Doorn ◽  
Frans G. A. van der Meché

2006 ◽  
Vol 148 (3) ◽  
pp. 399-400 ◽  
Author(s):  
Yasunori Wada ◽  
Atsushi Kamei ◽  
Yukiharu Fujii ◽  
Ken Ishikawa ◽  
Shoichi Chida

2006 ◽  
Vol 119 (14) ◽  
pp. 1230-1232 ◽  
Author(s):  
Xi-bao ZHANG ◽  
Yu-qing HE ◽  
Hua ZHOU ◽  
Quan LUO ◽  
Chang-xing LI

2014 ◽  
Vol 1 (1) ◽  
pp. 13
Author(s):  
Kazu Ode ◽  
Yoshinori Taniguchi ◽  
Yoshitaka Kumon ◽  
Yoshio Terada

We report a case of successful high-dose intravenous immunoglobulin (IVIG) use in a patient with refractory polyarteritis nodosa (PAN). Treatments with prednisolone (PSL) and various types of immunosuppressants including methotrexate (MTX) and intravenous cyclophosphamide (IVCY) were unsuccessful, and then, high-dose IVIG therapy was added. High-dose IVIG therapy improved all symptoms including high fever, arthralgia, mononeuritis multiplex and indurated erythema due to PAN. Moreover, serum inflammatory markers were also normalized. High-dose IVIG is maintaining complete remission for PAN without flare-up for additional 4 years. Therefore, high-dose IVIG therapy might be considered as a first-line therapy in patients with PAN or alternative therapy in refractory PAN.


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