1865-P: Dual Chemokine Receptor CCR2/CCR5 Antagonist Cenicriviroc Ameliorates Lipotoxicity-Induced Insulin Resistance and NASH in Mice

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1865-P
Author(s):  
TSUGUHITO OTA ◽  
GUANLIANG CHEN ◽  
MAYUMI NAGASHIMADA
Keyword(s):  
Insulin Resistance ◽  
Chemokine Receptor ◽  
Ccr5 Antagonist ◽  
Chemokine Receptor Ccr2

Discovery and Mapping of an Intracellular Antagonist Binding Site at the Chemokine Receptor CCR2

2014 ◽  
Vol 86 (4) ◽  
pp. 358-368 ◽  
Author(s):  
Annelien J.M. Zweemer ◽  
Julia Bunnik ◽  
Margo Veenhuizen ◽  
Fabiana Miraglia ◽  
Eelke B. Lenselink ◽  
...  
Keyword(s):  
Binding Site ◽  
Chemokine Receptor ◽  
Antagonist Binding ◽  
Chemokine Receptor Ccr2

scholarly journals The chemokine receptor CCR2 maintains plasmacytoid dendritic cell homeostasis

2017 ◽  
Vol 192 ◽  
pp. 72-78 ◽  
Author(s):  
Oriane Cédile ◽  
Line Østerby Jørgensen ◽  
Ida Frank ◽  
Agnieszka Wlodarczyk ◽  
Trevor Owens
Keyword(s):  
Dendritic Cell ◽  
Chemokine Receptor ◽  
Plasmacytoid Dendritic Cell ◽  
Cell Homeostasis ◽  
Chemokine Receptor Ccr2

scholarly journals Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT

FEBS Journal ◽  
2014 ◽  
Vol 281 (24) ◽  
pp. 5552-5566 ◽  
Author(s):  
Kaori Esaki ◽  
Sosuke Yoshinaga ◽  
Tatsuichiro Tsuji ◽  
Etsuko Toda ◽  
Yuya Terashima ◽  
...  
Keyword(s):  
Chemokine Receptor ◽  
Terminal Region ◽  
Structural Basis ◽  
Chemokine Receptor Ccr2

Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis

2004 ◽  
Vol 11 (7) ◽  
pp. 445-449 ◽  
Author(s):  
T. L. Sorensen ◽  
R. M. Ransohoff ◽  
R. M. Strieter ◽  
F. Sellebjerg
Keyword(s):  
Multiple Sclerosis ◽  
Chemokine Receptor ◽  
Active Multiple Sclerosis ◽  
Chemokine Receptor Ccr2

Total Synthesis of Anibamine, a Novel Natural Product as a Chemokine Receptor CCR5 Antagonist

2007 ◽  
Vol 9 (10) ◽  
pp. 2043-2046 ◽  
Author(s):  
Guo Li ◽  
Karen Watson ◽  
Robert W. Buckheit ◽  
Yan Zhang
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Chemokine Receptor ◽  
Ccr5 Antagonist ◽  
Chemokine Receptor Ccr5 ◽  
Receptor Ccr5

Deletion of the chemokine receptor CCR2 attenuates foreign body reaction to implants in mice

2014 ◽  
Vol 95 ◽  
pp. 37-45 ◽  
Author(s):  
Pollyana R. Castro ◽  
Suzane M. Marques ◽  
Celso T.R. Viana ◽  
Paula P. Campos ◽  
Mônica A.N.D. Ferreira ◽  
...  
Keyword(s):  
Foreign Body ◽  
Chemokine Receptor ◽  
Foreign Body Reaction ◽  
Chemokine Receptor Ccr2
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