63-OR: The Physiological Effects of Extrapancreatic Glucagon in Totally Pancreatectomized Patients Evaluated Using Glucagon Receptor Antagonism

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 63-OR
Author(s):  
CAROLINE T.B. JUEL ◽  
ASGER B. LUND ◽  
JENS F. REHFELD ◽  
NICOLAI JACOB WEWER ALBRECHTSEN ◽  
JENS J. HOLST ◽  
...  
Keyword(s):  
Physiological Effects ◽  
Glucagon Receptor ◽  
Receptor Antagonism

Glucagon receptor antagonism increases mouse pancreatic δ-cell mass through cell proliferation and duct-derived neogenesis

2019 ◽  
Vol 512 (4) ◽  
pp. 864-870 ◽  
Author(s):  
Liangbiao Gu ◽  
Xiaona Cui ◽  
Shan Lang ◽  
Haining Wang ◽  
Tianpei Hong ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cell Mass ◽  
Glucagon Receptor ◽  
Receptor Antagonism

1952-P: Glucagon Receptor Antagonism Increases Plasma Amino Acids and Glucagon

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1952-P ◽  
Author(s):  
SOFIE HAEDERSDAL ◽  
NICOLAI JACOB WEWER ALBRECHTSEN ◽  
ASGER B. LUND ◽  
KATRINE D. GALSGAARD ◽  
MARIE WINTHER-SOERENSEN ◽  
...  
Keyword(s):  
Amino Acids ◽  
Plasma Amino Acids ◽  
Glucagon Receptor ◽  
Receptor Antagonism

255-OR: ADA Presidents’ Select Abstract: Glucagon Receptor Antagonism Stimulates Beta-Cell Proliferation in Mouse and Human Islets

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 255-OR
Author(s):  
KATIE C. COATE ◽  
ERICK SPEARS ◽  
CHUNHUA DAI ◽  
SCOTT WISNIEWSKI ◽  
GREG POFFENBERGER ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Beta Cell ◽  
Human Islets ◽  
Beta Cell Proliferation ◽  
Glucagon Receptor ◽  
Receptor Antagonism ◽  
Select Abstract

Glucagon Receptor Antagonism-Mediated β-Cell Regeneration as an Effective Anti-Diabetic Therapy

2021 ◽  
Author(s):  
Yannan Xi ◽  
Benbo song ◽  
Iris Ngan ◽  
Mark Humphrey ◽  
Yan Wang ◽  
...  
Keyword(s):  
Cell Regeneration ◽  
Β Cell ◽  
Glucagon Receptor ◽  
Receptor Antagonism

Glucagon receptor antagonism promotes the production of gut proglucagon-derived peptides in diabetic mice

Peptides ◽  
2020 ◽  
Vol 131 ◽  
pp. 170349
Author(s):  
Shan Lang ◽  
Rui Wei ◽  
Tianjiao Wei ◽  
Liangbiao Gu ◽  
Jin Feng ◽  
...  
Keyword(s):  
Diabetic Mice ◽  
Glucagon Receptor ◽  
Receptor Antagonism

115-LB: Liver-Derived FGF21 Mediates the Promoting Effect of Glucagon Receptor Antagonism on Beta-Cell Regeneration in Type 2 Diabetic Mice

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 115-LB
Author(s):  
XIAONA CUI ◽  
TIANJIAO WEI ◽  
JIN FENG ◽  
JIN YANG ◽  
HAI YAN ◽  
...  
Keyword(s):  
Beta Cell ◽  
Cell Regeneration ◽  
Diabetic Mice ◽  
Promoting Effect ◽  
Glucagon Receptor ◽  
Receptor Antagonism ◽  
Beta Cell Regeneration ◽  
Type 2 Diabetic

128-LB: Effects of Glucagon Receptor Antagonism (GRA) on Ketone Body Formation during Insulinopenia in Type 1 Diabetes (T1D)

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 128-LB
Author(s):  
SCHAFER C. BOEDER ◽  
DANIEL G. INES ◽  
LESLIE CARTER ◽  
ERIN R. GIOVANNETTI ◽  
DEBRA ARMSTRONG ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Ketone Body ◽  
Glucagon Receptor ◽  
Receptor Antagonism ◽  
Body Formation

Individual and Combined Glucose-Lowering Effects of Glucagon Receptor Antagonism and Sodium-Glucose Cotransporter 2 Inhibition

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1942-P ◽  
Author(s):  
SOFIE HAEDERSDAL ◽  
ASGER B. LUND ◽  
HENRIK MAAGENSEN ◽  
ELISABETH NIELSEN-HANNERUP ◽  
JENS J. HOLST ◽  
...  
Keyword(s):  
Glucagon Receptor ◽  
Glucose Lowering ◽  
Receptor Antagonism ◽  
Sodium Glucose Cotransporter

scholarly journals Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet

Diabetologia ◽  
2007 ◽  
Vol 50 (7) ◽  
pp. 1453-1462 ◽  
Author(s):  
M. Sörhede Winzell ◽  
C. L. Brand ◽  
N. Wierup ◽  
U. G. Sidelmann ◽  
F. Sundler ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
High Fat Diet ◽  
Islet Function ◽  
High Fat ◽  
Glucagon Receptor ◽  
Receptor Antagonism

Individual and Combined Glucose-Lowering Effects of Glucagon Receptor Antagonism and Dipeptidyl Peptidase-4 Inhibition

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 274-LB
Author(s):  
SOFIE HAEDERSDAL ◽  
ASGER B. LUND ◽  
ELISABETH NIELSEN-HANNERUP ◽  
HENRIK MAAGENSEN ◽  
JENS J. HOLST ◽  
...  
Keyword(s):  
Dipeptidyl Peptidase ◽  
Glucagon Receptor ◽  
Glucose Lowering ◽  
Receptor Antagonism ◽  
Dipeptidyl Peptidase 4
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