66-LB: Greater Time Spent in Hypoglycemia during Night Compared with Day during Intensified Training in Professional Cyclists with Type 1 Diabetes—A Prospective Observational Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 66-LB ◽  
Author(s):  
OTHMAR MOSER ◽  
MAX L. ECKSTEIN ◽  
OLIVIA MCCARTHY ◽  
MICHAEL RIDDELL ◽  
FEDERICO Y. FONTANA ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Observational Study ◽  
Prospective Observational Study

scholarly journals Evaluation of Web-Based and In-Person Methods to Recruit Adults with Type 1 Diabetes for a Mobile Exercise Intervention: Prospective Observational Study (Preprint)

JMIR Diabetes ◽  
10.2196/28309 ◽  
2021 ◽  
Author(s):  
Garrett I Ash ◽  
Stephanie Griggs ◽  
Laura Nally ◽  
Matthew Stults-Kolehmainen ◽  
Sangchoon Jeon ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Exercise Intervention ◽  
Web Based

scholarly journals Glycemic responses to strenuous training in male professional cyclists with type 1 diabetes: a prospective observational study

2020 ◽  
Vol 8 (1) ◽  
pp. e001245 ◽  
Author(s):  
Olivia McCarthy ◽  
Max L Eckstein ◽  
Sam N Scott ◽  
Federico Y Fontana ◽  
Mark P Christiansen ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Exercise Training ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Strenuous Exercise ◽  
Physiological Data ◽  
P Value ◽  
Nocturnal Hypoglycemia ◽  
Increased Risk

IntroductionThis prospective observational study sought to establish the glycemic, physiological and dietary demands of strenuous exercise training as part of a 9-day performance camp in a professional cycling team with type 1 diabetes (T1D).Research design and methodsSixteen male professional cyclists with T1D on multiple daily injections (age: 27±4 years; duration of T1D: 11±5 years; body mass index: 22±2 kg/m2; glycated hemoglobin: 7%±1% (50±6 mmol/mol); maximum rate of oxygen consumption: 73±4 mL/kg/min) performed road cycle sessions (50%–90% of the anaerobic threshold, duration 1–6 hours) over 9 consecutive days. Glycemic (Dexcom G6), nutrition and physiological data were collected throughout. Glycemic data were stratified into predefined glycemic ranges and mapped alongside exercise physiology and nutritional parameters, as well as split into daytime and night-time phases for comparative analysis. Data were assessed by means of analysis of variance and paired t-tests. A p value of ≤0.05 (two-tailed) was statistically significant.ResultsHigher levels of antecedent hypoglycemia in the nocturnal hours were associated with greater time spent in next-day hypoglycemia overall (p=0.003) and during exercise (p=0.019). Occurrence of nocturnal hypoglycemia was associated with over three times the risk of next-day hypoglycemia (p<0.001) and a twofold risk of low glucose during cycling (p<0.001). Moreover, there was trend for a greater amount of time spent in mild hypoglycemia during the night compared with daytime hours (p=0.080).ConclusionThe higher prevalence of nocturnal hypoglycemia was associated with an increased risk of next-day hypoglycemia, which extended to cycle training sessions. These data highlight the potential need for additional prebed carbohydrates and/or insulin dose reduction strategies around exercise training in professional cyclists with T1D.Trial registration numberDRKS00019923.

scholarly journals Progression of microalbuminuria in type 1 diabetes: Ten-year prospective observational study

2005 ◽  
Vol 68 (4) ◽  
pp. 1446-1450 ◽  
Author(s):  
Peter Rossing ◽  
Philip Hougaard ◽  
Hans-Henrik Parving
Keyword(s):  
Type 1 Diabetes ◽  
Observational Study ◽  
Prospective Observational Study

157-OR: People with Type 1 Diabetes and Impaired Awareness of Hypoglycemia Have a Delayed Reaction to Perform a Glucose Scan during Hypoglycemia: A Prospective Observational Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 157-OR
Author(s):  
OTHMAR MOSER ◽  
HARIS ZIKO ◽  
HESHAM ELSAYED ◽  
DANIEL A. HOCHFELLNER ◽  
TINA POETTLER ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Delayed Reaction ◽  
Impaired Awareness
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