Blastomycosis-like pyoderma: a diagnostic as well as therapeutic challenge

Author(s):  
Ujjwal Kumar ◽  
Krishnendra Varma ◽  
Shashank Bhargava
2017 ◽  
Author(s):  
Daniela Magalhaes ◽  
Cesar Esteves ◽  
Maria Manuel Costa ◽  
Pedro Rodrigues ◽  
Davide Carvalho

2018 ◽  
Author(s):  
Alexandra Mirica ◽  
Rodica Petris ◽  
Radu Mirica ◽  
Sorin Paun ◽  
Corin Badiu ◽  
...  

2020 ◽  
Vol 13 (5) ◽  
pp. e234490
Author(s):  
Evan C Chen ◽  
Jonathan A Stefely ◽  
Bimalangshu R Dey ◽  
Walter H Dzik

Haemophagocytic lymphohistiocytosis (HLH) can be a rapidly fatal disease. Current treatment in adults is extrapolated from the HLH-2004 protocol that specifies a regimen of etoposide, dexamethasone and cyclosporine. However, HLH presents as a spectrum of disease severity. A therapeutic challenge arises for milder cases where the harms of potent chemotherapy such as etoposide may outweigh its benefit. We present a case of an adult with HLH who developed significant pancytopenia but was otherwise not critically ill and who responded to treatment with a chemotherapy-sparing approach consisting of intravenous immunoglobulins and corticosteroids alone. The case illustrates that tailored therapy may allow effective treatment of the disorder while minimising therapy-related toxicities.


Author(s):  
Enzo Emanuelli ◽  
Maria Baldovin ◽  
Claudia Zanotti ◽  
Sara Munari ◽  
Luca Denaro ◽  
...  

AbstractWhile the so-called pseudoaneurysms can result from arterial injury during trans-sphenoidal surgery or after a trauma, spontaneous aneurysms of cavernous–internal carotid artery (CICA) are rare. Symptoms vary and the differential diagnosis with other, more frequent, sellar lesions is difficult. We describe three cases of misdiagnosed CICA spontaneous aneurysm. In two cases the onset was with neuro-ophthalmological manifestations, classifiable as “cavernous sinus syndrome.” The emergency computed tomography scan did not show CICA aneurysm and the diagnosis was made by surgical exploration. The third patient came to our attention with a sudden severe unilateral epistaxis; endonasal surgery revealed also in this case a CICA aneurysm, eroding the wall and protruding into the sphenoidal sinus. When the onset was with a cavernous sinus syndrome, misdiagnosis exposed two patients to potential serious risk of bleeding, while the patient with epistaxis was treated with embolization, using coils and two balloons. Intracavernous nontraumatic aneurysms are both a diagnostic and therapeutic challenge, because of their heterogeneous onset and risk of rupture, potentially lethal. Intracavernous aneurysms can be managed with radiological follow-up, if asymptomatic or clinically stable, or can be surgically treated with endovascular or microsurgical techniques.


2021 ◽  
Vol 51 (7) ◽  
pp. 1191-1192
Author(s):  
Manu Juneja ◽  
Benjamin Solomon ◽  
Gerard G. Hanna

Dermatology ◽  
2010 ◽  
Vol 221 (1) ◽  
pp. 6-14 ◽  
Author(s):  
Paolo Gisondi ◽  
Ilaria Tinazzi ◽  
Micol Del Giglio ◽  
Giampiero Girolomoni

2021 ◽  
Vol 9 (4) ◽  
pp. 2048-2052
Author(s):  
Fateen Ata ◽  
Saad Javed ◽  
Bassam Muthanna ◽  
Ines dakhlia ◽  
Ammara Bint I Bilal ◽  
...  

1994 ◽  
Vol 19 (6) ◽  
pp. 998-1002 ◽  
Author(s):  
Daniel T. Altman ◽  
John D. Lubahn ◽  
Phyllis J. Kuhn

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