FEATURES OF VEGETATIVE STATUS IN FEMALE ADOLESCENTS WITH CHRONIC PELVIC PAIN SYNDROME

Chronic pelvic pain syndrome (CPPS) in adolescent girls is a common pathology that reduces the quality of life and disrupts their social adaptation. Objective of the research: to study causative factors of CPPS in female adolescents to assess the vegetative status (VS) and autonomic reactivity (AR). Materials and methods: the examination results of 90 girls with CPPS are presented. The VS was investigated using Kerdo index and cardiointervalography. Results: рathology of the urinary system was detected in 12 patients, gynecological dysfunctions were determined in 24 girls, the adhesions of the pelvic organs were registered in 9 girls, and pathology of the gastrointestinal tract was the reason of CPPS in 45 female adolescents. Initial sympathicotonia was found in 63 patients. While AR assessing a predominance of the sympathetic part was recorded in all patients, where hypersympathicotonic AR was registered in 27 girls. Conclusions: CPPS in adolescent girls is combined with sympathicotonic reactivity, and in some cases with hypersymptotic, AR, which requires correction in order to increase the efficacy of treatment of the main disease.

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Lower urinary tract dysfunction in adolescent girls with chronic pelvic pain syndrome

PEDIATRIA Journal named after G N SPERANSKY ◽

10.24110/0031-403x-2017-96-5-55-60 ◽

2017 ◽

Vol 96 (5) ◽

pp. 55-60

Author(s):

A.V. Pisklakov ◽

◽

V.S. Plaksina ◽

N.I. Pavlenko ◽

A.S. Shevlakov ◽

...

Keyword(s):

Urinary Tract ◽

Adolescent Girls ◽

Pelvic Pain ◽

Lower Urinary Tract ◽

Chronic Pelvic Pain ◽

Chronic Pelvic Pain Syndrome ◽

Pain Syndrome ◽

Lower Urinary Tract Dysfunction ◽

Pelvic Pain Syndrome ◽

Lower Urinary

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Features of the vegetative status and quality of life in patients with external genital endometriosis and chronic pelvic pain syndrome

Journal of obstetrics and women s diseases ◽

10.17816/jowd6845-12 ◽

2019 ◽

Vol 68 (4) ◽

pp. 5-12

Author(s):

Darya E. Kuznetsova ◽

Semyon V. Prokopenko ◽

Tatyana A. Makarenko

Keyword(s):

Quality Of Life ◽

Pelvic Pain ◽

Chronic Pelvic Pain ◽

Short Form ◽

Chronic Pelvic Pain Syndrome ◽

Pain Syndrome ◽

Reproductive Age ◽

Pelvic Pain Syndrome ◽

Vegetative Status

Hypothesis/aims of study. Chronic pelvic pain syndrome (CPPS) in patients with external genital endometriosis (EGE) has a mixed pathogenetic mechanism of formation, including nociceptive and neuropathic components. However, there is still no clear correlation between the severity of pain and the degree of EGE. Of particular importance in pain chronization is the imbalanced autonomic nervous system (ANS) forming complex psychosomatic status, which patients experience as stress. This condition reduces the quality of life and causes social disadaptation, which exacerbates the pathological picture of the disease and diminishes the effect of pathogenetic treatment of EGE. We aimed to investigate the features of the vegetative status and assess the quality of life in patients with EGE complicated by CPPS and with a painless course of the disease. Study design, materials, and methods. The study included 135 patients of reproductive age with grade III/IV EGE (r-AFS classification): 105 of them with CPPS and 30 without this syndrome. All these individuals underwent special ANS function testing and were assessed for the quality of life according to the Medical Outcomes Study Questionnaire Short Form 36 Health Survey (SF-36). Results. The features of the vegetative status in patients with EGE complicated by CPPS were identified, such as the predominance of the sympathicotonic type of vegetative reactivity, high scores of vegetative dysfunction syndrome (in groups of patients with CPPS in almost 100% of cases), as well as high levels of reactive and personal anxiety (p < 0.05). In addition, women with EGE and CPPS have significantly reduced quality of life compared to patients with EGE and without CPPS. Conclusion. The presence of suprasegmental and segmental ANS disorders in women with EGE and CPPS partly explains the mechanisms of pain syndrome chronization. The identified features are likely to be the cause of ineffective relief of pain syndrome in the EGE pathogenetic treatment algorithms. The reduced quality of life of such patients dictates the need to develop an effective treatment regimen for EGE and CPPS. This therapy should include drugs of central action that stop the neuropathic component of the pain syndrome, which is based on the imbalance of ANS parameters.

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