scholarly journals Combined hepatoblastoma and yolk sac tumor of the liver

2020 ◽  
Vol 19 (1) ◽  
pp. 92-99
Author(s):  
M. M. Morozova ◽  
A. V. Varlamov ◽  
O. V. Dolzhansky ◽  
A. V. Filin ◽  
D. S. Burmistrov ◽  
...  
Keyword(s):  
Morphological Structure ◽  
Personal Data ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Histological Structure ◽  
Beta Catenin ◽  
Right Lobe ◽  
Mitotic Figures ◽  
The Right

A 6-year-old patient was admitted to the Petrovsky National Research Center of Surgery in Moscow, diagnosed with hepatoblastoma (HB) of the right lobe of the liver and after undergoing 4 cycles of SIOPEL (super PLADO) pre-operative chemotherapy. An immunohistochemistry test, performed after liver resection, revealed a rare combination of mixed epithelial and mesenchymal hepatoblastoma and yolk sac tumor. The epithelial component of HB consisted of highly differentiated fetal cells, while the mesenchymal component consisted of osteoid. The morphological structure of the second lesion corresponded to yolk sac tumor. Both tumors had regressive changes conditioned by chemotherapy: these changes were most pronounced in HB. In the highly differentiated fetal component of HB it was possible to detect a weak focal perinuclear alpha-fetoprotein expression, HepPar expression, membranous expression of beta-catenin and diffuse glutamine synthetase expression. Mitotic figures were not determined. The node of the yolk sac tumor had the characteristic histological structure of an endodermal sinus tumor with a hepatoid component. In the main tumor node and its nodular elements in the fibrovascular stroma it was possible to identify alpha-fetoprotein expression, CD34, nuclear and cytoplasmic expression of beta-catenin, CDX2, as well as a rare expression of PLAP and multi-cytokeratin, and mitotic activity was high (21 in 10 high power fields, 400x magnification). In the existing literature available to us, there is only one observation of combined hepatoblastoma and yolk sac tumor. Parents patients agreed to use personal data, including the fotos, in research and publications.

scholarly journals A Case Report of Yolk Sac Tumor in Cerebellar Hemisphere and Review of Literature

2020 ◽  
Author(s):  
Yuting Zhang ◽  
Lusheng Li ◽  
Ling He
Keyword(s):  
Case Report ◽  
Histopathological Examination ◽  
Case Reports ◽  
Yolk Sac ◽  
Alpha Fetoprotein ◽  
Yolk Sac Tumor ◽  
Cerebellar Hemisphere ◽  
Review Of Literature ◽  
Intracranial Germ Cell Tumor ◽  
The Right

Abstract Background: Yolk sac tumor also known as endodermal sinus tumor, is a rare intracranial germ cell tumor. We reported a case of yolk sac tumor in cerebellar hemisphere, and reviewed associated literatures. The majority of tumor locations are near the midline. On review of literature, very few case reports of intracranial yolk sac tumor have been published, and there is only one case report has described a yolk sac tumor arising from the cerebellum. Case presentation: A two years old boy admitted to our hospital due to headache and unsteady gait for six days. CT and MRI demonstrated a tumor in the right cerebellar hemisphere, and the blood and cerebrospinal fluid alpha-fetoprotein were found increased. It was diagnosed as yolk sac tumor after operation comfirmed by histopathological examination. Postoperative chemotherapy was performed, and the patient suffered no tumor recurrence one year and a half after the surgery. Conclusions: The clinical characteristics and imaging diagnosis of intracranial yolk sac tumor are lack of specificity, the comfirmed diagnosis is depending on the combination of elevated alpha-fetoprotein and histopathological examination.

scholarly journals Morpho-histological comparative study of the liver in White-eared bulbul (Pycnonotus leucotis), Mallard duck (Anas platyrhynchos), and Gull (Larus canus)

2018 ◽  
Vol 41 (2) ◽  
pp. 94-99
Author(s):  
Khalid Ibrahim Abd Al-Khazraji
Keyword(s):  
Food Environment ◽  
Left Lobe ◽  
Histological Structure ◽  
Central Vein ◽  
Mallard Duck ◽  
Hepatic Parenchyma ◽  
Anatomical Features ◽  
Right Lobe ◽  
Hepatic Portal ◽  
The Right

     This study was conducted to compare some of anatomical features and histological structure of the liver in three species of birds that varied in their size, taxonomy, and food environment. The study revealed that the liver in the mallard, gull and white-eared bulbul was bilobed big gland, and the left lobe was smaller than the right one. It was observed that the two lobes in mallard were undivided, while the right lobe in gull has two parts, whereas the left lobe in white-eared bulbul is subdivided into two parts. Histologically, the liver capsule in gull appeared thicker than other two species. The hepatic parenchyma was not shown to be clearly defined lobules in three species. The hepatocytes were organized radially around the central vein as plates or cords of one-two cell thick in mallard and gull, and of two-several cell thick in white-eared bulbul, and those plates were separated by blood sinusoids. It turned out that the hepatic portal triads were less numerous in white-eared bulbul compared with other two species. It was found that there are differences in measurements of some histological structures of the liver among the three species.

scholarly journals Ultrasound case of the day. Endodermal sinus tumor (yolk sac tumor) of the right ovary.

Radiographics ◽  
1986 ◽  
Vol 6 (4) ◽  
pp. 734-737
Author(s):  
M A Sandler ◽  
R Walter ◽  
G H Beute ◽  
A H Haggar ◽  
B L Madrazo ◽  
...  
Keyword(s):  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Endodermal Sinus Tumor ◽  
The Right ◽  
Sinus Tumor

scholarly journals Severe Biliary Hyperplasia Associated with Liver Fluke Infection in an Adult Alpaca

2002 ◽  
Vol 39 (5) ◽  
pp. 592-594 ◽  
Author(s):  
A. N. Hamir ◽  
B. B. Smith
Keyword(s):  
Fasciola Hepatica ◽  
Parasitic Infection ◽  
Granulomatous Inflammation ◽  
Hepatic Atrophy ◽  
Fluke Infection ◽  
Right Lobe ◽  
Mitotic Figures ◽  
The Right ◽  
Liver Fluke Infection ◽  
Lama Pacos

An adult alpaca ( Lama pacos) had a locally extensive area of hepatic atrophy involving the right lobe. Grossly, the atrophic lobe was light tan and firm and contained small, raised, white to yellow, partially mineralized circular nodules predominantly at the periphery of the atrophic tissue. Microscopically, viable hepatocytes were not present in the atrophic area, and the tissue consisted of diffuse biliary epithelial proliferation without any evidence of nuclear or cellular atypia or the presence of mitotic figures. The circular mineralized nodules consisted of granulomatous inflammation with intralesional parasitic ova surrounded by fibrous connective tissue. Morphologically, the ova were compatible with those of Fasciola hepatica. The severe biliary hyperplasia was unusual, and it was not clear whether it was caused by an aberrant host response to the parasitic infection or whether it was an unrelated event.

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