scholarly journals Extramammary Paget’s Disease in the Pubic Region: a Case Report

2013 ◽  
Vol 5 (4) ◽  
pp. 171-176
Author(s):  
Slobodan Stojanović ◽  
Nada Vučković ◽  
Pavle Jeremić ◽  
Biljana Jeremić

Abstract The authors present a case of a patient with extramammary Paget’s disease in the pubic region treated by a dermatologist with a private practice for almost 4 years before incisional biopsy was performed. A thorough examination showed no evidence of malignancies of internal organs, whereas definite diagnosis was made by excision of the entire skin lesion and histopathological analysis. With regard to multiple criteria, findings in our patient were consistent with current literature data, but interestingly, the primary extramammary Paget’s disease has not spread into deeper tissues.

2021 ◽  
pp. 176-183
Author(s):  
Thanachat Rutnumnoi ◽  
Charussri Leeyaphan

Extramammary Paget’s disease (EMPD) is a rare intraepithelial neoplasm that occurs in apocrine-bearing areas of skin. Most EMPD patients initially present with chronic pruritic eczematous lesions involving genitalia, perineum and perianal area. Familial form of EMPD is extremely rare. Several genetic mutations have been proposed but specific modes of inheritance are still unknown. This article reports two cases of familial extramammary Paget’s disease in female siblings.


Skin Cancer ◽  
2020 ◽  
Vol 35 (2) ◽  
pp. 71-75
Author(s):  
Naohisa ICHIKI ◽  
Hirofumi NIWA ◽  
Kanako MATSUYAMA ◽  
Takaaki ITAZU ◽  
Noriyuki NAKAYAMA ◽  
...  

Burns ◽  
2010 ◽  
Vol 36 (8) ◽  
pp. e145-e147 ◽  
Author(s):  
Daofeng Ben ◽  
Liu Liu ◽  
Bing Ma ◽  
Yongyan Li ◽  
Zhaofan Xia

Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1029
Author(s):  
Christoforos S. Kosmidis ◽  
Christina Sevva ◽  
Panagiota Roulia ◽  
Charilaos Koulouris ◽  
Nikolaos Varsamis ◽  
...  

Extramammary Paget’s disease is a rare condition, affecting 6.5% of all patients with Paget’s disease. The most common extramammary site is the vulvar area. Although diagnosis in some patients is difficult to set, early diagnosis is of high importance in order to detect the irreversible progression of the lesion early and prevent distant metastasis. An 89-year-old female and a 69-year-old female presented within three months with an eczematous lesion with leukoplakia in the vulva. The incisional biopsy of the skin revealed extramammary Paget’s disease. Both patients underwent a surgical wide local excision of the lesion and the specimens were sent for histopathological examination. Extramammary Paget’s disease has a high potential for distant malignancies and local recurrence, dictating that surgical excision is the most efficient treatment. The rareness of the condition and the diagnostic difficulties underline the need for early skin biopsy, which is the most efficient diagnostic tool.


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