scholarly journals СУТОЧНАЯ МНОГОКАНАЛЬНАЯ РН-ИМПЕДАНСОМЕТРИЯ ПИЩЕВОДА В ДИАГНОСТИКЕ ГАСТРОЭЗОФАГЕАЛЬНОЙ РЕФЛЮКСНОЙ БОЛЕЗНИ (КЛИНИЧЕСКИЕ СЛУЧАИ)

2021 ◽  
Vol 5 (2) ◽  
pp. 197-204
Author(s):  
Ya. A. Kolodzeyskiy ◽  
◽  
V. I. Shishko ◽  
А. A. Karpovich ◽  
Yu. Ya. Shelkovich ◽  
...  
Keyword(s):  
Gold Standard ◽  
Ph Monitoring ◽  
Urgent Problem ◽  
Diagnostic Equipment ◽  
Esophageal Diseases ◽  
Esophageal Ph ◽  
Acid Breakthrough ◽  
Impedance Monitoring ◽  
Upper Gastrointestinal

Background. Gastroesophageal reflux disease (GERD) is an urgent problem of modern gastroenterology as well as the most common pathology of the upper gastrointestinal tract; it is a chronic disease that significantly reduces the patient's quality of life, increases the risk of developing Barrett's esophagus and esophageal adenocarcinoma. Objective. To assess the potentials of multichannel intraluminal pH impedance monitoring in the diagnosis of esophageal diseases. Material and methods. In 3 patients with clinical and endoscopic signs of GERD esophageal multichannel intraluminal pH-impedance monitoring was performed using the diagnostic equipment Digitrapper pH-Z from Given Imaging (USA). Results. 24-hour esophageal pH monitoring enabled to verify the diagnosis of GERD, to reveal a hypersensitive esophagus and manifestations of nocturnal acid breakthrough. Conclusions. Multichannel intraluminal pH-impedance monitoring is the "gold standard" for the diagnosis of esophageal diseases; it significantly expands opportunities of gastroenterologists in the treatment of GERD.

Tu1801 Correlation Between Oropharyngeal pH Monitoring and Esophageal pH-Impedance Monitoring in Patients With Suspected GERD-Related Extra-Esophageal Symptoms

2013 ◽  
Vol 144 (5) ◽  
pp. S-849
Author(s):  
Giorgia Mazzoleni ◽  
Cristian Vailati ◽  
Pier Alberto Testoni ◽  
Sandro M. Passaretti
Keyword(s):  
Ph Monitoring ◽  
Esophageal Ph ◽  
Impedance Monitoring

Correlation between oropharyngeal pH-monitoring and esophageal pH-impedance monitoring in patients with suspected GERD-related extra-esophageal symptoms

2014 ◽  
Vol 26 (11) ◽  
pp. 1557-1564 ◽  
Author(s):  
G. Mazzoleni ◽  
C. Vailati ◽  
D. G. Lisma ◽  
P. A. Testoni ◽  
S. Passaretti
Keyword(s):  
Ph Monitoring ◽  
Esophageal Ph ◽  
Impedance Monitoring

S1907 Recording Accuracy of a New ISFET Disposable Catheter pH Electrode Design Compared to a “Gold Standard” Glass pH Catheter in Ambulatory Esophageal pH Monitoring Studies

2009 ◽  
Vol 136 (5) ◽  
pp. A-289-A-290
Author(s):  
Anita Fareeduddin ◽  
Peter J. Kahrilas ◽  
John E. Pandolfino ◽  
Thomas R. Parks ◽  
Daniel Luger ◽  
...  
Keyword(s):  
Gold Standard ◽  
Ph Monitoring ◽  
Esophageal Ph Monitoring ◽  
Electrode Design ◽  
Standard Glass ◽  
Esophageal Ph ◽  
Ph Electrode

scholarly journals What Is Nonacid Reflux Disease?

2011 ◽  
Vol 25 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Martin A Storr
Keyword(s):  
Clinical Practice ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Gold Standard ◽  
Standard Treatment ◽  
Ph Monitoring ◽  
Nonacid Reflux ◽  
Impedance Monitoring ◽  
Esophageal Sphincter

Proton pump inhibitors (PPIs) are the gold standard treatment for gastroesophageal reflux disease. In clinical practice, failure of PPIs occurs frequently, and may affect up to 30% of patients in a typical gastroenterology practice. Multichannel impedance monitoring combined with pH monitoring helps to detect nonacid reflux, and if symptoms correlate with these nonacid reflux episodes, nonacid reflux disease can be diagnosed. In contrast to PPIs, reflux inhibitors target transient lower esophageal sphincter relaxations, which are involved in the pathophysiology of reflux disease and may be the appropriate future treatment for nonacid reflux disease. The present article discusses the current understanding of nonacid reflux disease, its diagnosis and treatment.

Prospective Study on the Incidence of Chronic Ear Complaints Related to Gastroesophageal Reflux and on the Outcome of Antireflux Therapy

2002 ◽  
Vol 111 (10) ◽  
pp. 933-938 ◽  
Author(s):  
Johan Poelmans ◽  
Jan Tack ◽  
Louw Feenstra
Keyword(s):  
Gastroesophageal Reflux ◽  
Ph Monitoring ◽  
Upper Gastrointestinal Endoscopy ◽  
Esophageal Ph ◽  
Tube Dysfunction ◽  
Esophageal Sphincter ◽  
Antireflux Therapy ◽  
Dual Probe ◽  
Upper Gastrointestinal

Over a 2-year period (1997 to 1999), 5 consecutive adult patients with chronic refractory secretory otitis media (CSOM) and 16 with a chronic refractory feeling of pressure in the ear(s) (CRFP) thought to be related to concomitant eustachian tube dysfunction were prospectively studied for coexisting gastroesophageal reflux (GER). All patients underwent an extensive standardized otorhinolaryngological examination, ambulatory 24-hour dual-probe esophageal pH monitoring with a distal pH probe 5 cm and a proximal probe 20 cm above the lower esophageal sphincter, and upper gastrointestinal endoscopy. Most of them also underwent esophageal manometry. All patients with CSOM and 12 of the 16 patients with CRFP had evidence of GER. Only 5 patients experienced heartburn or regurgitation. All patients responded very well to antireflux therapy with omeprazole 20 mg twice per day (40 mg twice per day in 2 patients) accompanied by conservative antireflux measures, ie, complete cessation of their middle ear complaints. This study demonstrates the role of GER in the pathogenesis of refractory CSOM and CRFP and the effectiveness of sustained antireflux therapy.

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