Effects of coexisting upper gastrointestinal symptoms on daily life and quality of life in patients with gastroesophageal reflux disease symptoms

Esophagus ◽  
2021 ◽  
Author(s):  
Kimio Isshi ◽  
Hiroto Furuhashi ◽  
Akio Koizumi ◽  
Koji Nakada
Keyword(s):  
Quality Of Life ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Daily Life ◽  
Gastrointestinal Symptoms ◽  
Disease Symptoms ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

scholarly journals Acute Effects of Red Chili, a Natural Capsaicin Receptor Agonist, on Gastric Accommodation and Upper Gastrointestinal Symptoms in Healthy Volunteers and Gastroesophageal Reflux Disease Patients

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3740
Author(s):  
Tanisa Patcharatrakul ◽  
Chatchai Kriengkirakul ◽  
Tawatchai Chaiwatanarat ◽  
Sutep Gonlachanvit
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Healthy Volunteers ◽  
Reflux Disease ◽  
Gastrointestinal Symptoms ◽  
Emission Computed Tomography ◽  
Transient Receptor Potential Vanilloid ◽  
Gastric Accommodation ◽  
Upper Gastrointestinal Symptoms ◽  
Upper Gastrointestinal

The effects of chili on gastric accommodation (GA) in gastroesophageal reflux disease (GERD) patients have not been explored. Methods: In total, 15 healthy volunteers (HV) and 15 pH-positive non-erosive GERD (NERD) patients underwent single-photon emission computed tomography after ingesting 2 g of chili or placebo in capsules in a randomized double-blind crossover fashion with a one-week washout period. GA was the maximal postprandial gastric volume (GV) after 250 mL of Ensure® minus the fasting GV. Upper gastrointestinal symptoms were evaluated by using a visual analog scale. Results: NERD patients but not HV had significantly greater GA after chili compared to a placebo (451 ± 89 vs. 375 ± 81 mL, p < 0.05). After chili, the postprandial GVs at 10, 20, and 30 min in NERD patients were significantly greater than HV (10 min, 600 ± 73 vs. 526 ± 70 mL; 20 min, 576 ± 81 vs. 492 ± 78 mL; 30 min, 532 ± 81 vs. 466 ± 86 mL, all p < 0.05). In NERD, chili was associated with significantly less satiety, more severe abdominal burning (p < 0.05), and a trend of more severe heartburn (p = 0.06) compared to the placebo. In HV, postprandial symptoms after chili and placebo ingestion were similar (p > 0.05). Conclusions: Chili enhanced GA in NERD patients but not in HV. This suggests that the modulation of GA in NERD is abnormal and likely involves transient receptor potential vanilloid 1 (TRPV1) sensitive pathways.

Managing Patients with Gastroesophageal Reflux Disease on Primary Step of Medical Care

2016 ◽  
pp. 114-117
Author(s):  
Liubov Skrypnyk ◽  
Nataliia Matkovska ◽  
Nataliia Chaplinska
Keyword(s):  
Quality Of Life ◽  
Clinical Practice ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Medical Care ◽  
Reflux Disease ◽  
Treatment Algorithms ◽  
Severity Of The Disease ◽  
Upper Gastrointestinal

In order to improve the quality and efficiency of primary medical care are widely deployed standards, diagnostics and treatment algorithms. The leader among the diseases of the upper gastrointestinal tract is gastroesophageal reflux disease. To improve the diagnosis and treatment of patients in the clinical practice of a general practitioner – family medicine is recommended to use questionnaires that allows to estimate the severity of the disease, the correct to refer patient for further diagnostic steps. This will allow prescribe the appropriate therapeutic schemes, to reduce the frequency of recurrences and improve the patient’s quality of life.

Impact of gastroesophageal reflux disease symptoms on the quality of life in pregnant women

2017 ◽  
Vol 29 (8) ◽  
pp. 892-896 ◽  
Author(s):  
Sara Fill Malfertheiner ◽  
Birgit Seelbach-Göbel ◽  
Serban-Dan Costa ◽  
Wolfgang Ernst ◽  
Edith Reuschel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Pregnant Women ◽  
Reflux Disease ◽  
Disease Symptoms
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