Involvement of cytochrome P450 2D in the formation of serotonin in the brain: in vivo and in vitro study

2016 ◽  
Author(s):  
Anna Haduch
Keyword(s):  
Cytochrome P450 ◽  
In Vitro Study ◽  
Vitro Study ◽  
The Brain

Involvement of cytochrome P450 2D in the formation of serotonin in the brain: in vivo and in vitro study

2016 ◽  
Vol 26 ◽  
pp. S262
Author(s):  
A. Haduch ◽  
E. Bromek ◽  
J. Wójcikowski ◽  
K. Gołembiowska ◽  
W.A. Daniel
Keyword(s):  
Cytochrome P450 ◽  
In Vitro Study ◽  
Vitro Study ◽  
The Brain

The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: An in vitro study

2013 ◽  
Vol 67 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Anna Haduch ◽  
Ewa Bromek ◽  
Anna Sadakierska-Chudy ◽  
Jacek Wójcikowski ◽  
Władysława A. Daniel
Keyword(s):  
Cytochrome P450 ◽  
In Vitro Study ◽  
Vitro Study ◽  
The Brain

The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study

2010 ◽  
Vol 626 (2-3) ◽  
pp. 171-178 ◽  
Author(s):  
Ewa Bromek ◽  
Anna Haduch ◽  
Władysława A. Daniel
Keyword(s):  
Cytochrome P450 ◽  
In Vitro Study ◽  
Vitro Study ◽  
The Brain

Effects of TSH and calcitriol on bone metabolism: in vivo and in vitro study

2014 ◽  
Author(s):  
Ivo Dumic-Cule ◽  
Dunja Rogic ◽  
Damir Jezek ◽  
Lovorka Grgurevic ◽  
Slobodan Vukicevic
Keyword(s):  
Bone Metabolism ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals Effect of cannulation site on emboli travel during cardiac surgery

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Mira Puthettu ◽  
Stijn Vandenberghe ◽  
Stefanos Demertzis
Keyword(s):  
Cardiac Surgery ◽  
In Vitro Study ◽  
Blood Stream ◽  
Air Bubbles ◽  
Arterial Tree ◽  
Air Bubble ◽  
Cannulation Site ◽  
The Brain

Abstract Background During cardiac surgery, micro-air emboli regularly enter the blood stream and can cause cognitive impairment or stroke. It is not clearly understood whether the most threatening air emboli are generated by the heart-lung machine (HLM) or by the blood-air contact when opening the heart. We performed an in vitro study to assess, for the two sources, air emboli distribution in the arterial tree, especially in the brain region, during cardiac surgery with different cannulation sites. Methods A model of the arterial tree was 3D printed and included in a hydraulic circuit, divided such that flow going to the brain was separated from the rest of the circuit. Air micro-emboli were injected either in the HLM (“ECC Bubbles”) or in the mock left ventricle (“Heart Bubbles”) to simulate the two sources. Emboli distribution was measured with an ultrasonic bubble counter. Five repetitions were performed for each combination of injection site and cannulation site, where air bubble counts and volumes were recorded. Air bubbles were separated in three categories based on size. Results For both injection sites, it was possible to identify statistically significant differences between cannulation sites. For ECC Bubbles, axillary cannulation led to a higher amount of air bubbles in the brain with medium-sized bubbles. For Heart Bubbles, aortic cannulation showed a significantly bigger embolic load in the brain with large bubbles. Conclusions These preliminary in vitro findings showed that air embolic load in the brain may be dependent on the cannulation site, which deserves further in vivo exploration.

Inhibition of Cyclosporin A-Induced Gingival Overgrowth by Azithromycin Through Phagocytosis: An In Vivo and In Vitro Study

2004 ◽  
Vol 75 (3) ◽  
pp. 380-387 ◽  
Author(s):  
Jeong-Won Paik ◽  
Chang-Sung Kim ◽  
Kyoo-Sung Cho ◽  
Jung-Kiu Chai ◽  
Chong-Kwan Kim ◽  
...  
Keyword(s):  
Cyclosporin A ◽  
In Vitro Study ◽  
Vitro Study ◽  
Gingival Overgrowth
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