Hyaluronic Acid Filler Injection as an Alternative to Surgery for the Correction of Canine Entropion

A 3-year-old intact female Old English Bulldog and 5-month-old spayed female Chow Chow were diagnosed with entropion. Instead of surgery, hyaluronic acid (HA) filler injections were performed to correct the entropion and relieve the associated symptoms. We used the layered feathering technique, which was effective for the administration of the HA into the tissues for the correction of canine entropion. The eyelid positions were maintained for 6-8 months after the procedures. These cases demonstrate that HA filler injections relieve clinical signs quickly and effectively, though temporarily, in patients with entropion

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Hyaluronic Acid Injections as Nonsurgical Alternative in case of Delayed Diagnosis of Malar Arch Fracture: Case Report and Literature Review

Case Reports in Surgery ◽

10.1155/2019/1360741 ◽

2019 ◽

Vol 2019 ◽

pp. 1-4

Author(s):

Raffaele Rauso ◽

Giorgio Lo Giudice ◽

Nicola Zerbinati ◽

Gianpaolo Tartaro

Keyword(s):

Hyaluronic Acid ◽

Case Report ◽

Functional Impairment ◽

Delayed Diagnosis ◽

Facial Trauma ◽

Facial Fracture ◽

Filler Injection ◽

First Case ◽

Filler Injections ◽

Fracture Diagnosis

Background. In this article, we describe a nonsurgical approach based on hyaluronic acid filler injection to restore the facial features of a delayed diagnosis of malar fracture. We analyze the differences between surgical and nonsurgical solution: in case of early detection, the surgical approach is the gold standard of treatment. However, in cases of delayed facial fracture diagnosis without functional impairment, nonsurgical procedures could be considered an alternative tool as we show in the present case report. Aims. The aim of this study is to underline the importance of a complete aesthetic restoration in patients treated for noncosmetic purposes. Patients/Methods. We present a case of a 26-year-old male patient with a delayed diagnosis of malar fracture without functional impairment that was treated with hyaluronic acid (HA) filler injections. Results. The patient was followed up for 1 year showing stable results for the first 8 months; at the 12-month follow-up, a touch-up was suggested due to partial resorption of the filler. Conclusion. This is the first case describing a facial fracture treated with HA injections for only recontouring purposes. We assess that nonsurgical cosmetic procedures could be considered a “new” tool in the process of facial rehabilitation but only when functional problems are not associated with facial trauma.

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A Safe Doppler Ultrasound–Guided Method for Nasolabial Fold Correction With Hyaluronic Acid Filler

Aesthetic Surgery Journal ◽

10.1093/asj/sjaa153 ◽

2020 ◽

Cited By ~ 1

Author(s):

Won Lee ◽

Ji-Soo Kim ◽

Hyoung-Jin Moon ◽

Eun-Jung Yang

Keyword(s):

Hyaluronic Acid ◽

Doppler Ultrasound ◽

Rating Scale ◽

Vascular Complications ◽

Facial Artery ◽

Nasolabial Fold ◽

Filler Injection ◽

Ultrasound Evaluation ◽

Filler Injections ◽

Nasolabial Folds

Abstract Background Injection of hyaluronic acid filler, a common procedure for nasolabial fold correction, poses a risk of vascular compromise, which can result in skin necrosis and blindness. Objectives The aim of this study was to examine the facial arterial pathway in real time by Doppler ultrasound to avoid arterial complications during filler injections. Methods The facial artery pathway of 40 patients (80 nasolabial folds; 2 men and 38 women; mean age, 46.5 years; range, 28-72 years) was examined by Doppler ultrasound before hyaluronic acid filler injection. On the basis of this ultrasound evaluation, the filler injection targeted the subdermal, subcutaneous, and deep to submuscular layers by bypassing the facial artery. The efficacy of the filler injection was evaluated for each patient. Results The facial artery was detected lateral to the nasolabial fold in 31% of patients; it was detected beneath the nasolabial fold in the other patients as follows: subdermal layer, 13%; subcutaneous layer, 29%; muscular layer, 24%; and submuscular layer, 4%. The mean [standard deviation] Wrinkle Severity Rating Scale score was 3.68 [0.76] before injection and 2.28 [0.78] at 3 months after injection. Two patients experienced unilateral bruising of the nasolabial fold, which resolved after 2 weeks without treatment. Conclusions Doppler ultrasound can be considered as pretreatment tool for the prevention of vascular complications during filler injections to correct nasolabial folds. Level of Evidence: 4

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A Consensus on Minimizing the Risk of Hyaluronic Acid Embolic Visual Loss and Suggestions for Immediate Bedside Management

Aesthetic Surgery Journal ◽

10.1093/asj/sjz312 ◽

2019 ◽

Vol 40 (9) ◽

pp. 1009-1021 ◽

Cited By ~ 5

Author(s):

Greg J Goodman ◽

Mark R Magnusson ◽

Peter Callan ◽

Stefania Roberts ◽

Sarah Hart ◽

...

Keyword(s):

Hyaluronic Acid ◽

Best Practice ◽

Visual Loss ◽

Adverse Reactions ◽

Level Of Evidence ◽

Early Management ◽

Initial Management ◽

Filler Injection ◽

Filler Injections ◽

Review Current

Abstract Background Hyaluronic acid fillers have a satisfactory safety profile. However, adverse reactions do occur, and rarely intravascular injection may lead to blindness. Currently there is no internationally recognized consensus on the prevention or management of blindness from hyaluronic acid filler. Objectives The authors sought to give guidance on how to minimize the risk and optimize the management of this rare but catastrophic adverse reaction. Methods A multinational group of experts in cosmetic injectables from multiple disciplines convened to review current best practice and develop updated consensus recommendations for prevention and bedside intervention if visual loss occurs after cosmetic injection of hyaluronic acid filler. Results The consensus group provided specific recommendations focusing on the consenting process, prevention, and early management of visual impairment related to intravascular hyaluronic acid filler injection. Conclusions Although visual loss due to filler injections is rare, it is important that both patient and physician be aware of this risk. In this paper the authors describe methods and techniques available to reduce the risk and also document suggested initial management should a clinician find themselves in this situation. Level of Evidence: 5

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Meningomyelocoele in a Dog

Veterinary Pathology ◽

10.1177/030098587301000309 ◽

1973 ◽

Vol 10 (3) ◽

pp. 266-273 ◽

Cited By ~ 12

Author(s):

A. J. Parker ◽

C. S. Byerly

Keyword(s):

Spinal Cord ◽

Urinary Incontinence ◽

Old English ◽

Spinal Canal ◽

Clinical Signs ◽

Terminal Part ◽

Before And After ◽

Spinal Cord Function ◽

English Bulldog

An 8-month-old English Bulldog with focal and urinary incontinence was examined before and after death. There was nonfusion of the dorsal laminae of vertebra L, in the midline. Through this defect a small meningomyelocoele, and the terminal part of the spinal cord, emerged from the spinal canal. The clinical signs were attributed to damage of both pudendal nerves or their spinal cold segments. The dog had normal spinal cord function to all limbs.

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Asymptomatic Stroke After Hyaluronic Acid Filler Injection: Case Report and Literature Review

Aesthetic Surgery Journal ◽

10.1093/asj/sjaa381 ◽

2020 ◽

Author(s):

Ryan M Moore ◽

Melissa A Mueller ◽

Allison C Hu ◽

Gregory R D Evans

Keyword(s):

Hyaluronic Acid ◽

Vision Loss ◽

Facial Soft Tissue ◽

Tissue Ischemia ◽

Filler Injection ◽

Intraarterial Injection ◽

Facial Filler ◽

Vascular Compromise ◽

Filler Injections ◽

Soft Tissue Filler

Abstract Vascular compromise and blindness are reported but rare complications of facial soft tissue filler injections. Stroke is an even rarer complication resulting from intraarterial injection of fillers. We present a case of a patient suffering all three complications following hyaluronic acid filler injection: forehead skin vascular compromise, unilateral blindness, and ipsilateral subclinical strokes. Were it not for a stroke workup protocol, the incidental strokes may have otherwise gone undetected, suggesting the incidence of stroke from intraarterial injection may be higher than reported. Further, we review the literature and recommendations for prevention and management of threatened tissue ischemia and vision loss from facial filler injection.

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Hyaluronic acid injections in post-enucleation or evisceration socket syndrome: a case series

European Journal of Plastic Surgery ◽

10.1007/s00238-021-01855-9 ◽

2021 ◽

Author(s):

Renata Migliardi ◽

Alessandra Modugno ◽

Fabrizio Chirico ◽

Nicola Zerbinati ◽

Giovanni Francesco Nicoletti ◽

...

Keyword(s):

Hyaluronic Acid ◽

Case Series ◽

Outpatient Setting ◽

Level Of Evidence ◽

Upper Eyelid ◽

Filler Injection ◽

Tear Trough Deformity ◽

Vasovagal Response ◽

Superior Sulcus ◽

Therapeutic Study

Abstract Background One of the primary goals of enucleation and evisceration surgery is the restoration of an adequate orbital volume through the use of appropriately sized alloplastic or autogenous tissues. In patients inadequately treated, post-enucleation or evisceration socket syndrome occurs. Fillers are an ideal alternative for eyelid and eyebrow arcade volume enhancement since their injection is easily performed in an outpatient setting avoiding several complications. The aim of this study is to report the use of hyaluronic acid (HA) fillers to treat volume deficits of the upper and lower eyelids, projecting the brow arcade and reducing the asymmetry. Methods Thirteen patients (2 male, 11 female, mean age 32.7 years) were treated from June 2012 to May 2020. Non-surgical treatment by HA filler injection for aesthetic rehabilitation of deep superior sulcus, inferior tear trough deformity, and scleral show was performed. Results No complications as orbital-ache and/or vasovagal response were reported during the injections. Minor complications such as light swelling at the site of injection, self-resolved within 2 days, were recorded. Stable results were observed at follow-ups. In two cases, two successive treatments were required at 3 and 6 years from the first injection. Conclusions Hyaluronic acid fillers offer a versatile and safe method for replacing soft tissue lost from the upper eyelid/brow complex in cases of post-enucleation or evisceration socket syndrome. Level of evidence: Level IV, therapeutic study.

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Hyaluronic Acid Fillers for Midface Augmentation: A Systematic Review

Facial Plastic Surgery ◽

10.1055/s-0041-1724122 ◽

2021 ◽

Author(s):

Lily N. Trinh ◽

Amar Gupta

Keyword(s):

Systematic Review ◽

Hyaluronic Acid ◽

Subcutaneous Tissue ◽

Age Groups ◽

Medical Subject Headings ◽

Mesh Terms ◽

Full Text Review ◽

Filler Injections ◽

Subjective Measurements ◽

Meta Analyses

AbstractInjectable fillers represent one of the most requested minimally invasive treatments to rejuvenate the aging face, and its popularity is steadily rising. A vast majority of filler treatments are with hyaluronic acid (HA). The aim of this systematic review is to evaluate patient outcomes, safety profile, and administration techniques of various HA fillers for malar augmentation. A systematic review of the published literature was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and included PubMed, Embase, and Science Direct databases. Medical Subject Headings (MeSH) terms used were “cheek” OR “midface” OR “malar” and “filler” OR “hyaluronic acid” OR “Juvederm” OR “Restylane” OR “Perlane” OR “Belotero.” The initial search identified 699 articles; 256 duplicates were removed. Additional 12 studies were identified from reference lists. A total of 455 were screened by title and abstract and 387 studies were eliminated based on criteria. Also, 68 articles underwent full-text review, and 18 articles were included in the final review and involved seven different HA formulations. Men and women from many age groups were highly satisfied with their results following HA treatment for midface augmentation up to 24 months. The most common adverse events included bruising, swelling, and tenderness, and typically lasted no more than 2 weeks. Upper cheek filler injections near the zygoma should be placed in the submuscular plane while lower cheek injections should be placed in the subcutaneous tissue. HA is an attractive choice for midface augmentation due to its high patient satisfaction, long-lasting effects, and low side-effect profile. Due to the variability in technique, level of expertise, and subjective measurements across studies, one optimal regimen could not be concluded. However, midface augmentation treatment should be personalized to each patient. Additional clinical trials are required to more conclusively determine the most appropriate approach for this procedure.

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