scholarly journals Estimation of the 18F-FDG Input Function in Mice by Use of Dynamic Small-Animal PET and Minimal Blood Sample Data

2007 ◽  
Vol 48 (12) ◽  
pp. 2037-2045 ◽  
Author(s):  
G. Z. Ferl ◽  
X. Zhang ◽  
H.-M. Wu ◽  
S.-C. Huang
PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205610 ◽  
Author(s):  
Lorena Cussó ◽  
Manuel Desco

2009 ◽  
Vol 50 (6) ◽  
pp. 966-973 ◽  
Author(s):  
A. S. Yu ◽  
H.-D. Lin ◽  
S.-C. Huang ◽  
M. E. Phelps ◽  
H.-M. Wu

2004 ◽  
Vol 31 (2) ◽  
pp. 251-256 ◽  
Author(s):  
Hiroshi Toyama ◽  
Masanori Ichise ◽  
Jeih-San Liow ◽  
Douglass C. Vines ◽  
Nicholas M. Seneca ◽  
...  

2009 ◽  
Vol 50 (11) ◽  
pp. 1848-1856 ◽  
Author(s):  
K. McLarty ◽  
A. Fasih ◽  
D. A. Scollard ◽  
S. J. Done ◽  
D. C. Vines ◽  
...  

2008 ◽  
Vol 35 (1) ◽  
pp. 143-150 ◽  
Author(s):  
Sang-Keun Woo ◽  
Tae Sup Lee ◽  
Kyeong Min Kim ◽  
June-Youp Kim ◽  
Jae Ho Jung ◽  
...  

Oncotarget ◽  
2016 ◽  
Vol 7 (19) ◽  
pp. 28247-28261 ◽  
Author(s):  
Valerie S. Honndorf ◽  
Stefan Wiehr ◽  
Anna-Maria Rolle ◽  
Julia Schmitt ◽  
Luisa Kreft ◽  
...  

2016 ◽  
Vol 58 (4) ◽  
pp. 611-616 ◽  
Author(s):  
Chi-Cheng Huang ◽  
Chun-Hu Wu ◽  
Ya-Yao Huang ◽  
Kai-Yuan Tzen ◽  
Szu-Fu Chen ◽  
...  

2016 ◽  
Vol 22 (3) ◽  
pp. 69-75 ◽  
Author(s):  
Khadidja Berradja ◽  
Nabil Boughanmi

Abstract In dynamic cardiac PET FDG studies the assessment of myocardial metabolic rate of glucose (MMRG) requires the knowledge of the blood input function (IF). IF can be obtained by manual or automatic blood sampling and cross calibrated with PET. These procedures are cumbersome, invasive and generate uncertainties. The IF is contaminated by spillover of radioactivity from the adjacent myocardium and this could cause important error in the estimated MMRG. In this study, we show that the IF can be extracted from the images in a rat heart study with 18F-fluorodeoxyglucose (18F-FDG) by means of Independent Component Analysis (ICA) based on Bayesian theory and Markov Chain Monte Carlo (MCMC) sampling method (BICA). Images of the heart from rats were acquired with the Sherbrooke small animal PET scanner. A region of interest (ROI) was drawn around the rat image and decomposed into blood and tissue using BICA. The Statistical study showed that there is a significant difference (p < 0.05) between MMRG obtained with IF extracted by BICA with respect to IF extracted from measured images corrupted with spillover.


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