Invasive Haemophilus influenzae Disease: Epidemiology and Clinical Spectrum Before Large-scale H. influenzae Type b Vaccination

1995 ◽  
Vol 27 (1) ◽  
pp. 63-67 ◽  
Author(s):  
Svante Hugosson ◽  
Sven-Arne Silfverdal ◽  
öjan Garpenholt ◽  
Elisabeth Esbjörner ◽  
Bo Lindquist ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Large Scale ◽  
Clinical Spectrum ◽  
Type B ◽  
Disease Epidemiology

Counterimmunoelectrophoresis of Urine for Diagnosis of Bacterial Pneumonia in Pediatric Outpatients

PEDIATRICS ◽  
1983 ◽  
Vol 71 (5) ◽  
pp. 780-783
Author(s):  
Ronald B. Turner ◽  
Frederick G. Hayden ◽  
J. Owen Hendley
Keyword(s):  
Haemophilus Influenzae ◽  
Bacterial Pneumonia ◽  
Clinical Spectrum ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Older Children ◽  
Pediatric Outpatients ◽  
Etiologic Diagnosis

Thirty-eight pediatric outpatients with pneumonia were studied by counterimmunoelectrophoresis for the presence of Haemophilus influenzae type b or pneumococcal antigenuria. Of the 38 patients eight (21%) hadH influenzae type b antigenuria and two (5%) had pneumococcal antigenuria. H influenzae, type b antigenuria was detected more frequently in patients <2 years of age than in older children. Urine counterimmunoelectrophoriesis appears to be a useful tool for the etiologic diagnosis of bacterial pneumonia and should facilitate further studies of the epidemiology, pathogenesis, and clinical spectrum of this disease.

Haemophilus influenzae type b disease in HIV-infected children: A review of the disease epidemiology and effectiveness of Hib conjugate vaccines

Vaccine ◽  
2010 ◽  
Vol 28 (7) ◽  
pp. 1677-1683 ◽  
Author(s):  
Punam Mangtani ◽  
Kim Mulholland ◽  
Shabir A. Madhi ◽  
Karen Edmond ◽  
Rosalyn O’Loughlin ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Conjugate Vaccines ◽  
Disease Epidemiology

scholarly journals Modelling transmission, immunity and disease of Haemophilus influenzae type b in a structured population

2004 ◽  
Vol 132 (5) ◽  
pp. 947-957 ◽  
Author(s):  
K. AURANEN ◽  
M. EICHNER ◽  
T. LEINO ◽  
A. K. TAKALA ◽  
P. H. MÄKELÄ ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Large Scale ◽  
Age Groups ◽  
Invasive Disease ◽  
Transmission Model ◽  
Haemophilus Influenzae Type ◽  
Care Group ◽  
Demographic Model ◽  
Type B ◽  
Sustained Effects

An individual-based stochastic simulation model was constructed to study the epidemiology of Haemophilus influenzae type b (Hib) transmission, immunity and invasive disease. Embedded in a demographic model, the transmission model of Hib carriage employs the most important social mixing patterns with three types of contact sites (family, day-care group, and school class). The model includes immunity against invasive Hib disease, initiated and boosted by Hib carriage and cross-reactive bacterial encounters. The model reproduces the observed age patterns in Hib carriage and disease in Finland before large-scale use of the Hib conjugate vaccines. The model was used to investigate characteristics of Hib transmission. The analysis emphasizes transmission between children and adults in families while pointing out the importance of pre-school and school-aged children in maintaining Hib circulation. Carriage in these age groups is thus identified as being essential to target for sustained effects of interventions by vaccination.

Sign in / Sign up

Export Citation Format

Share Document