Evidence that lack of ligand-binding domain correlates with nuclear distribution of unliganded human androgen receptor and loss of transactivation activity

Noriko Suzuki; Atsushi Imai

doi:10.3109/09513590.2011.569599

Evidence that lack of ligand-binding domain correlates with nuclear distribution of unliganded human androgen receptor and loss of transactivation activity

Gynecological Endocrinology ◽

10.3109/09513590.2011.569599 ◽

2011 ◽

Vol 27 (11) ◽

pp. 940-943

Author(s):

Noriko Suzuki ◽

Atsushi Imai

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Transactivation Activity ◽

Nuclear Distribution ◽

Human Androgen Receptor

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Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity

Protein Science ◽

10.1110/ps.051905906 ◽

2006 ◽

Vol 15 (5) ◽

pp. 987-999 ◽

Cited By ~ 149

Author(s):

Karine Pereira de Jésus-Tran ◽

Pierre-Luc Côté ◽

Line Cantin ◽

Jonathan Blanchet ◽

Fernand Labrie ◽

...

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Crystal Structures ◽

Binding Affinity ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Molecular Determinants ◽

Human Androgen Receptor

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Activation Function 2 in the Human Androgen Receptor Ligand Binding Domain Mediates Interdomain Communication with the NH2-terminal Domain

Journal of Biological Chemistry ◽

10.1074/jbc.274.52.37219 ◽

1999 ◽

Vol 274 (52) ◽

pp. 37219-37225 ◽

Cited By ~ 246

Author(s):

Bin He ◽

Jon A. Kemppainen ◽

Johannes J. Voegel ◽

Hinrich Gronemeyer ◽

Elizabeth M. Wilson

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Activation Function ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Terminal Domain ◽

Human Androgen Receptor ◽

Interdomain Communication

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Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226

Acta Crystallographica Section F Structural Biology and Crystallization Communications ◽

10.1107/s1744309106039340 ◽

2006 ◽

Vol 62 (11) ◽

pp. 1067-1071 ◽

Cited By ~ 26

Author(s):

Feng Wang ◽

Xiao-qin Liu ◽

He Li ◽

Kai-ni Liang ◽

Jeffrey N. Miner ◽

...

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Human Androgen Receptor

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Hormone-binding and solubility properties of fusion proteins containing the ligand-binding domain of the human androgen receptor

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/0960-0760(95)00273-1 ◽

1996 ◽

Vol 57 (3-4) ◽

pp. 251-257 ◽

Cited By ~ 3

Author(s):

B. Cooper ◽

J.A. Gruber ◽

M.J. McPhaul

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Fusion Proteins ◽

Binding Domain ◽

Ligand Binding Domain ◽

Hormone Binding ◽

Human Androgen Receptor

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Partial association of restriction polymorphism of the ligand binding domain of human androgen receptor in prostate cancer

Egyptian Journal of Medical Human Genetics ◽

10.1016/j.ejmhg.2015.09.004 ◽

2016 ◽

Vol 17 (2) ◽

pp. 223-228

Author(s):

Mohamed Hessien ◽

Ahmed El Barbary ◽

Saad el Gendy ◽

Amira Nabil

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Partial Association ◽

Restriction Polymorphism ◽

Human Androgen Receptor

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Mass Spectrometric Characterization of the Human Androgen Receptor Ligand-Binding Domain Expressed inEscherichia coli†

Biochemistry ◽

10.1021/bi010525j ◽

2001 ◽

Vol 40 (36) ◽

pp. 10756-10763 ◽

Cited By ~ 4

Author(s):

Zixin Zhu ◽

Robert R. Becklin ◽

Dominic M. Desiderio ◽

James T. Dalton

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Mass Spectrometric ◽

Binding Domain ◽

Ligand Binding Domain ◽

Inescherichia Coli ◽

Receptor Ligand ◽

Human Androgen Receptor

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Crystallization and preliminary X-ray analysis of the human androgen receptor ligand-binding domain with a coactivator-like peptide and selective androgen receptor modulators

Acta Crystallographica Section F Structural Biology and Crystallization Communications ◽

10.1107/s1744309108036683 ◽

2008 ◽

Vol 64 (12) ◽

pp. 1159-1162

Author(s):

Maxime Thauvin ◽

Catherine Robin-Jagerschmidt ◽

François Nique ◽

Patrick Mollat ◽

Damien Fleury ◽

...

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

X Ray ◽

Selective Androgen Receptor Modulators ◽

Receptor Modulators ◽

Human Androgen Receptor

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Structural Characterization of the Human Androgen Receptor Ligand-binding Domain Complexed with EM5744, a Rationally Designed Steroidal Ligand Bearing a Bulky Chain Directed toward Helix 12

Journal of Biological Chemistry ◽

10.1074/jbc.m705524200 ◽

2007 ◽

Vol 282 (42) ◽

pp. 30910-30919 ◽

Cited By ~ 42

Author(s):

Line Cantin ◽

Frédérick Faucher ◽

Jean-François Couture ◽

Karine Pereira de Jésus-Tran ◽

Pierre Legrand ◽

...

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Structural Characterization ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Helix 12 ◽

Human Androgen Receptor

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Structural studies on the human androgen receptor ligand-binding domain

Acta Crystallographica Section A Foundations of Crystallography ◽

10.1107/s0108767302093005 ◽

2002 ◽

Vol 58 (s1) ◽

pp. c200-c200

Author(s):

M. A. Carrondo

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Structural Studies ◽

Receptor Ligand ◽

Human Androgen Receptor

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Three-dimensional structure of homodimeric androgen receptor ligand-binding domain

Endocrine Abstracts ◽

10.1530/endoabs.42.il3 ◽

2016 ◽

Author(s):

Eva Estebanez Perpina

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Three Dimensional ◽

Binding Domain ◽

Ligand Binding Domain ◽

Dimensional Structure ◽

Receptor Ligand ◽

Three Dimensional Structure

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