Iatrogenic Cushing's syndrome and topical steroid therapy: case series and review of the literature

2013 ◽  
Vol 25 (6) ◽  
pp. 495-500 ◽  
Author(s):  
Sem Decani ◽  
Veronica Federighi ◽  
Elisa Baruzzi ◽  
Andrea Sardella ◽  
Giovanni Lodi
Keyword(s):  
Steroid Therapy ◽  
Cushing’S Syndrome ◽  
Topical Steroid ◽  
Case Series ◽  
Cushing's Syndrome ◽  
Review Of The Literature ◽  
Topical Steroid Therapy ◽  
Iatrogenic Cushing’S Syndrome

scholarly journals Cabergoline in severe ectopic or occult Cushing’s syndrome

2019 ◽  
Vol 181 (1) ◽  
pp. K1-K9 ◽  
Author(s):  
Mirela Diana Ilie ◽  
Véronique Raverot ◽  
François Tronc ◽  
Alexandre Vasiljevic ◽  
Françoise Borson-Chazot ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
Cushing’S Syndrome ◽  
Case Series ◽  
Cushing's Syndrome ◽  
Cushing's Disease ◽  
Review Of The Literature ◽  
Dopamine Receptor Agonists ◽  
Receptor Agonists ◽  
Potential Value

Context Cabergoline has been shown to have some effect in the treatment of moderate Cushing’s disease, but its effectiveness in Cushing’s syndrome of ectopic or occult origin remains to be investigated. Case series In this case series, cabergoline was used in combination with steroidogenesis inhibitors in nine patients with severe Cushing’s syndrome of ectopic or occult origin. Cabergoline’s effectiveness enabled rapid withdrawal of the steroidogenesis inhibitors and long-term control of the hypercortisolism in three of the cases. Review of the literature In the literature, we found only 11 cases of ectopic or occult Cushing’s syndrome treated with dopamine receptor agonists, alone or in combination. Yet of these 11 cases, 10 responded. Conclusions Although limited, the existing experience highlights the potential value of cabergoline in the treatment of ectopic or occult Cushing’s syndrome.

scholarly journals Iatrogenic Cushing’s Syndrome with Subsequent Adrenal Insufficiency in a Patient with Psoriasis Vulgaris Using Topical Steroids

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Suzan Demir Pektas ◽  
Gursoy Dogan ◽  
Nese Cinar
Keyword(s):  
Adrenal Insufficiency ◽  
Cushing’S Syndrome ◽  
Psoriasis Vulgaris ◽  
Topical Steroid ◽  
Cushing's Syndrome ◽  
Chronic Inflammatory Disease ◽  
High Dose ◽  
Topical Steroids ◽  
First Choice ◽  
Iatrogenic Cushing’S Syndrome

Iatrogenic Cushing’s syndrome (ICS) is usually related to prolonged and/or high-dose oral or parenteral steroid use. Psoriasis vulgaris (PV) is chronic inflammatory disease and characterized by periods of attack and remission. Topical steroid (TS) is the first choice of treatment for localized and mild PV. The development of systemic side effects of the steroids is usually not observed after TS application. But the risk of developing ICS still exists. In the literature, there are a few adult cases who developed ICS and subsequent adrenal insufficiency associated with TS. In this article, a male patient with PV developing ICS and secondary adrenal insufficiency after treatment of TS for 12 years is presented.

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