Pathogenesis of obstructive sleep apnea: Insights from upper airway imaging studies

Sleep Apnea ◽  
2016 ◽  
pp. 13-38
Author(s):  
Kunzang Doma Bhutia ◽  
Anandabrata Bose ◽  
Anjon Debnath

Introduction:  Hypopharyngeal  lipomas  are  rare  tumors  of  head  and  neck  which  present  with  vague  symptoms  like  dysphagia,  foreign  body  sensation  in  throat,  feeling  of  something  coming  to  the  throat  or mouth,  choking  sensations  or  with  symptoms of  obstructive  sleep  apnea.  These   tumors  can  cause  upper  airway  obstruction  and  even  asphyxial   deaths  presenting  as  medical   emergency.  Case report:  We  report  one  such  case  of  a  38  year  old  female  with  hypopharyngeal  lipoma  who  had  presented  to  us  with symptoms  of  dysphagia,  choking  episodes  and  foreign  body  sensation  in  throat. Discussion:   Laryngoscopic  examination   in  these  cases  is  diagnostic  to  assess   its  size  and  site  of  attachment.  Imaging  studies  like  CT scan  or  MRI  help  in  diagnosis.


ORL ◽  
2021 ◽  
pp. 1-8
Author(s):  
Lifeng Li ◽  
Demin Han ◽  
Hongrui Zang ◽  
Nyall R. London

<b><i>Objective:</i></b> The purpose of this study was to evaluate the effects of nasal surgery on airflow characteristics in patients with obstructive sleep apnea (OSA) by comparing the alterations of airflow characteristics within the nasal and palatopharyngeal cavities. <b><i>Methods:</i></b> Thirty patients with OSA and nasal obstruction who underwent nasal surgery were enrolled. A pre- and postoperative 3-dimensional model was constructed, and alterations of airflow characteristics were assessed using the method of computational fluid dynamics. The other subjective and objective clinical indices were also assessed. <b><i>Results:</i></b> By comparison with the preoperative value, all postoperative subjective symptoms statistically improved (<i>p</i> &#x3c; 0.05), while the Apnea-Hypopnea Index (AHI) changed little (<i>p</i> = 0.492); the postoperative airflow velocity and pressure in both nasal and palatopharyngeal cavities, nasal and palatopharyngeal pressure differences, and total upper airway resistance statistically decreased (all <i>p</i> &#x3c; 0.01). A significant difference was derived for correlation between the alteration of simulation metrics with subjective improvements (<i>p</i> &#x3c; 0.05), except with the AHI (<i>p</i> &#x3e; 0.05). <b><i>Conclusion:</i></b> Nasal surgery can decrease the total resistance of the upper airway and increase the nasal airflow volume and subjective sleep quality in patients with OSA and nasal obstruction. The altered airflow characteristics might contribute to the postoperative reduction of pharyngeal collapse in a subset of OSA patients.


2001 ◽  
Vol 164 (2) ◽  
pp. 250-255 ◽  
Author(s):  
R. JOHN KIMOFF ◽  
EMILIA SFORZA ◽  
VICTORIA CHAMPAGNE ◽  
LINDA OFIARA ◽  
DANIEL GENDRON

2004 ◽  
Vol 98 (4) ◽  
pp. 301-307 ◽  
Author(s):  
Bing Lam ◽  
Clara G.C Ooi ◽  
Wilfred C.G Peh ◽  
I Lauder ◽  
Kenneth W.T Tsang ◽  
...  

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