Differential expression of RAP2A/RAP2B in cancer of the vulva.
Keyword(s):
In these brief notes we document work using published microarray data (1, 2) to pioneer integrative transcriptome analysis comparing vulvar carcinoma to its tissue of origin, the vulva. We report the differential expression of RAP2A and RAP2B, members of the RAS oncogene family, encoded by RAP2A/RAP2B, in cancer of the vulva. RAP2A/RAP2B may be of pertinence to understanding transformation and disease progression in vulvar cancer (3).