scholarly journals HPV tests for cervical cancer screening in low resource settings: a protocol of a DTA systematic review

2020 ◽  
Author(s):  
Rana Magdi ◽  
Farida Elshafeey ◽  
Mohamed Elshebiny ◽  
Menna kamel ◽  
Yasmeen Gamal Abuelnaga ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Diagnostic Test ◽  
Diagnostic Test Accuracy ◽  
Cochrane Library ◽  
Test Accuracy ◽  
Low Resource Settings ◽  
Low Resource ◽  
Hpv Test

Background: Human Papillomavirus (HPV) tests for cervical cancer screening in low resource settings might improve early detection and preventive efforts. Objectives: To determine the diagnostic accuracy of HPV tests for detecting cervical intraepithelial neoplasia grade 2 or worse (CIN 2+) in low resource settings.Search strategy: we will search the Cochrane library, MEDLINE, CINAHL, Web of Science, and Scopus. We will search references of relevant studies. Selection criteria: We will include diagnostic test accuracy studies if women had an HPV test for cervical cancer screening, followed by verification with colposcopy and colposcopy-directed biopsy. The primary target is CIN2+. Data collection and analysis: Two authors will independently screen studies, extract data, and assess methodological quality. We will use bivariate diagnostic random-effects meta-analysis.Results: This is the protocol of a diagnostic test accuracy systematic review.Conclusions: Evidence will aid in making well-informed decisions for cervical cancer screening in low resource settings. Implications for research will be outlined for future studies.

Use of Smartphones as Adjuvant Tools for Cervical Cancer Screening in Low-Resource Settings

2015 ◽  
Vol 19 (4) ◽  
pp. 295-300 ◽  
Author(s):  
Dominique Ricard-Gauthier ◽  
Anna Wisniak ◽  
Rosa Catarino ◽  
Annabelle Faure van Rossum ◽  
Ulrike Meyer-Hamme ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Low Resource Settings ◽  
Low Resource

scholarly journals Speculum-Free Callascope for Cervical Self-Visualization: Acceptability, Feasibility, and Improved Awareness of the Reproductive System

2020 ◽  
Vol 6 (Supplement_1) ◽  
pp. 50-50
Author(s):  
Mary Elizabeth Dotson ◽  
Mercy Asiedu ◽  
Nimmi Ramanujam
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Low Cost ◽  
Invasive Cervical Cancer ◽  
Imaging Device ◽  
Low Resource Settings ◽  
Low Resource ◽  
Attitudes And Practices ◽  
Home Based

PURPOSE Invasive cervical cancer is preventable, yet it affects 500,000 women worldwide each year, and more than one half these women die. Barriers to cervical cancer screening include a lack of awareness of cervical cancer and the cervix, fear of the speculum, and lack of women-centric technologies. We developed a low-cost (approximately $50), cervix-imaging device called the Callascope, which consists of an imaging component, camera, and inserter that obviates the need for a speculum and enables self-insertion. Studies are lacking regarding women’s willingness to independently image their cervix and women’s ability to effectively use the Callascope for self-imaging. METHODS We conducted two studies: in-depth interviews to assess the willingness to self-image the cervix, perceptions of the Callascope, and knowledge, attitudes, and practices toward cervical cancer screening; and home-based self-cervix imaging with the Callascope where women recorded an audio reflection on their experience. RESULTS Participants in interviews (n = 12) and home study (n = 12) all indicated a preference for the Callascope over the speculum. Interview data demonstrated that 53% of participants had little knowledge of basic reproductive anatomy, and only 17% of participants understood that human papillomavirus was a direct cause of cervical cancer. Self-exam data showed that 83% of participants were able to visualize their cervix with the Callascope on the first try and 100% were able to do so by the end of the study. Of participants, 100% indicated that the home exam was an empowering and informative experience. CONCLUSION The Callascope is more comfortable than the speculum and women are able to successfully image their cervices from home without the need for a speculum. With improved diagnostic capabilities, the Callascope could be used by medical providers for clinical exams, particularly in low-resource settings, as a low-cost and more comfortable alternative to the SOC. The Callascope enables home self-screening for cervical cancer and a better understanding of one’s body, which could make screening more accessible in low-resource settings.

Cervical Cancer Screening in Low-Resource Settings

2017 ◽  
Vol 39 (12) ◽  
pp. 1183-1184
Author(s):  
Laurie Elit ◽  
Gina Ogilvie ◽  
Marrette Lee
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Low Resource Settings ◽  
Low Resource

scholarly journals The prevalence of hrHPV among the isolated community in the Highland of Bario, Sarawak, East Malaysia

2019 ◽  
Author(s):  
Abigail Rembui Jerip ◽  
Mardiana Kipli ◽  
Cheng-Siang Tan
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Outreach Program ◽  
Low Resource Settings ◽  
Dna Test ◽  
Hpv Dna ◽  
Low Resource ◽  
Cervical Swab

Abstract Background Malaysia has introduced the free Pap smear as the primary cervical cancer screening program since the 1960s but has only achieved the national coverage of 22%. The coverage would be much lower in the rural communities especially in Sarawak where many villages are still inaccessible by road, and communities are living in low resource settings. In this study, we have evaluated Qiagen’s careHPV system as a point-of-care HPV diagnostic test together with the visualization using acetic acid (VIA) in the isolated community in the Highland of Bario which are predominantly from the Kelabit ethnicity. Methods Women attending the cervical cancer outreach program were recruited. Consent was obtained and a cervical swab was clinician-collected and screened for High-risk HPV DNA using the careHPV system. Cervical examination using VIA was offered to all women age <50-year. hrHPV positive women were recruited during their follow-up session and the second cervical swab was collected for HPV genotyping using consensus primer-nested PCR to elucidate the infecting HPV genotypes. Results Seventy-five women from the age of 27-83 (mean age 55) attended the cervical cancer screening clinic and 8% (n=6/75) of them were positive for hrHPV. Only 33 women were screened using VIA and 21.2% (n=7/33) were found to be positive. A majority of the women (58.6%) were above the age of 50-year and not recommended for VIA to be performed. Thus, it was not feasible to correlate the results obtained from the HPV DNA test and VIA. Only four hrHPV positive women returned for follow-up and genotyping revealed HPV52 in 2 of four women tested suggesting that HPV52 may be the predominant genotype in Bario. Conclusions The careHPV system is portable and can be used in low resource settings as long as reliable electricity is available. We found that careHPV DNA test is more objective compared to VIA and can be used to screen women outside the recommended eligible age. This is especially true for older women in the rural who have never had any form of cervical cancer screening before.

scholarly journals The Utility of Urine-Based Sampling for Cervical Cancer Screening in Low-Resource Settings

2019 ◽  
Vol 20 (8) ◽  
pp. 2409-2413
Author(s):  
Sasidharanpillai Sabeena ◽  
Santhosh Kuriakose ◽  
Damodaran Binesh ◽  
Jazeel Abdulmajeed ◽  
Giselle Dsouza ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Low Resource Settings ◽  
Low Resource
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